Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome.
Canberra, Australia. In J Transl Med, 2014
RESULTS: Eleven novel and rare functional variants were identified in cases but not in controls, harboured in: MACF1, KIAA0754, DUSP12, ICA1, CELA1, LRP1/STAT6, GRIN3B, ANKLE1, TMEM161A, and FKRP.
Islet autoantigens: structure, function, localization, and regulation.
Ann Arbor, United States. In Cold Spring Harb Perspect Med, 2011
In this context, we evaluate the biochemical nature and immunogenicity of the major autoantigens in T1D including (pro)insulin, GAD65, ZnT8, IA2, and ICA69.
T-cell responses to autoantigens in IDDM. The search for the Holy Grail.
Leiden, Netherlands. In Diabetes, 1996
In the last few years, considerable progress has been made with regard to the identification and characterization of candidate autoantigens recognized by autoantibodies; several of these candidate autoantigens are recognized by T-cells, including insulin, GAD65 and GAD67, heat-shock protein 65 (hsp65), and islet-cell antigen 69 (ICA69).