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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Ring finger protein 19A

p38, p38 protein, Dorfin
The protein encoded by this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquitin ligase that is localized in Lewy bodies, a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein binds and ubiquitylates synphilin 1 (SNCAIP) which is an interacting protein of alpha synuclein in neurons and a major component of Lewy bodies. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Feb 2012] (from NCBI)
Top mentioned proteins: MAPK, V1a, JNK, ERK, ERK1
Papers using p38 antibodies
A HPLC-DAD method for the simultaneous determination of five marker components in the traditional herbal medicine Bangpungtongsung-san
An Won G. et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2010
... (Santa Cruz, CA, USA), and ERK1/2, phospho-ERK1/2, JNK, phospho-JNK, p38, and phospho-p38 antibodies were purchased from Cell Signaling Technology, Inc ...
Diallyl trisulfide inhibits phorbol ester-induced tumor promotion, activation of AP-1, and expression of COX-2 in mouse skin by blocking JNK and Akt signaling.
Wong Nai Sum, In PLoS ONE, 2009
... Primary antibodies for rabbit polyclonal p-cJun, p-ERK and p-p38 were purchased from Cell Signaling Technology (Boston, MA) ...
Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells.
Ye Juan et al., In Molecular Vision, 2009
... were phospho-specific monoclonal antibodies for extracellular signal-regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 kinase and rabbit antibodies from Santa Cruz Biotechnology (Santa Cruz, CA); nitrocellulose ...
Glycyrrhetinic acid inhibits ICAM-1 expression via blocking JNK and NF-kappaB pathways in TNF-alpha-activated endothelial cells.
Zimmer Jacques, In PLoS ONE, 2009
... Antibody against p38 and phosphorylated-p38 were purchased from Santa Cruz Biotechnology (Santa cruz, CA, USA) ...
ABL-N-induced apoptosis in human breast cancer cells is partially mediated by c-Jun NH2-terminal kinase activation
Han M et al., In Cell Death & Disease, 2009
... -terminal kinase (p-JNK), phospho-p38 MAP kinase (p-p38) and p38 were obtained from Cell Signaling Technology (Beverly, MA, USA) ...
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Papers on p38
Discovery of 2-((3-amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a potent, selective and orally available BCR-ABL/SRC/p38 kinase inhibitor for Chronic Myeloid Leukemia.
Liu et al., In J Med Chem, Feb 2016
UNASSIGNED: Starting from a dihydropyrimidopyrimidine core scaffold based compound 27 (GNF-7), we discovered a highly potent (ABL1: IC50 of 70 nM) and selective (S score (1) = 0.02) BCR-ABL inhibitor 18a (CHMFL-ABL-053).
Aryl hydrocarbon receptor-driven signals inhibit collagen synthesis in the gut.
Monteleone et al., Roma, Italy. In Eur J Immunol, Feb 2016
TGF-β1 or TNF-α-induced activation of p38 and ERK1/2 MAP kinases was decreased by Ficz and increased by CH223191.
Signaling Network Controlling Androgenic Repression of c-Fos in Prostate Adenocarcinoma Cells.
Danielpour et al., United States. In J Biol Chem, Feb 2016
Moreover, our results support that p38(MAPK), PI3K and PKCδ are involved in the androgenic regulation of c-Fos through controlling MEK/ERK.
Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics.
Mueller et al., Bern, Switzerland. In Hum Reprod Update, Feb 2016
RESULTS: The current literature on intracellular kinases activated by the endometriotic environment can be summarized into three main pathways that could be targeted for treatments: the canonical IKKβ/NFκB pathway, the MAPK pathways (ERK1/2, p38 and JNK) and the PI3K/AKT/mTOR pathway.
Beyond Ussing's chambers: Contemporary thoughts on integration of transepithelial transport.
Turner et al., Chicago, United States. In Am J Physiol Cell Physiol, Jan 2016
Intermediates in this process include activation of p38 MAPK, the apical Na(+)-H(+) exchanger NHE3, and myosin light chain kinase (MLCK).
Treatment of chronic kidney disease using a traditional Chinese medicine, Flos Abelmoschus manihot (Linnaeus) Medicus (Malvaceae).
Chen et al., Beijing, China. In Clin Exp Pharmacol Physiol, Jan 2016
The renoprotective effects of Flos A. manihot are related to inhibition of caspase-3 and caspase-8 overexpression, reduction of the infiltration of ED1+ and ED3+ macrophages, downregulation of oxidative stress, inhibition of the p38 mitogen-activated protein kinase and serine/threonine kinase pathways and suppression of transforming growth factor-β1 and tumour necrosis factor-α expression.
New insights into the activation, interaction partners and possible functions of MK5/PRAK.
Seternes et al., Tromsø, Norway. In Front Biosci, Dec 2015
MAP kinase-activated protein kinase 5 (MK5) was first described as a downstream target of the p38 MAP kinase pathway leading to its alternative acronym of p38-regulated/activated protein kinase (PRAK).
Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.
Kim et al., Ch'ŏnan, South Korea. In Plos One, Dec 2015
Furthermore, Tβ4 peptide inhibited osteoclast differentiation, osteoclast-specific gene expression, and p38, ERK, and JNK phosphorylation and NF-κB activation in RANKL-stimulated BMMs.
24-Week Exposure to Oxidized Tyrosine Induces Hepatic Fibrosis Involving Activation of the MAPK/TGF-β1 Signaling Pathway in Sprague-Dawley Rats Model.
Zhao et al., Wuxi, China. In Oxid Med Cell Longev, Dec 2015
Besides, O-Tyr distinctly increased the phosphorylation of p38 and ERK2 MAPKs and enhanced fibrosis-related TGF-β1 and Smad2/3 levels.
Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Ashwell et al., Bethesda, United States. In Nat Med, Nov 2015
T cells possess a unique mechanism of p38 mitogen-activated protein kinase (MAPK) activation downstream of T cell receptor (TCR) engagement through the phosphorylation of Tyr323 (pY323).
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.
Yaffe et al., Cambridge, United States. In Cancer Cell, Nov 2015
In p53-mutant tumors, cell cycle checkpoints are rewired, leading to dependency on the p38/MK2 pathway to survive DNA-damaging chemotherapy.
Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.
Linker et al., Bochum, Germany. In Immunity, Nov 2015
We report that long-chain fatty acids (LCFAs) enhanced differentiation and proliferation of T helper 1 (Th1) and/or Th17 cells and impaired their intestinal sequestration via p38-MAPK pathway.
The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory.
Ishii et al., Tsukuba, Japan. In Nat Immunol, Oct 2015
Treatment with lipopolysaccharide, which mimics bacterial infection, induced phosphorylation of ATF7 via the kinase p38, which led to the release of ATF7 from chromatin and a decrease in repressive histone H3K9me2 marks.
The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.
Means et al., United States. In Nat Immunol, May 2015
Macrophages from Treml4(-/-) mice were hyporesponsive to TLR7 agonists and failed to produce type I interferons due to impaired phosphorylation of the transcription factor STAT1 by the mitogen-activated protein kinase p38 and decreased recruitment of the adaptor MyD88 to TLR7.
MAPK-Activated Protein Kinases (MKs): Novel Insights and Challenges.
Gaestel, Hannover, Germany. In Front Cell Dev Biol, 2014
Downstream of MAPKs, such as classical/atypical ERKs and p38 MAPKs, but not of JNKs, signaling is often mediated by protein kinases which are phosphorylated and activated by MAPKs and, therefore, designated MAPK-activated protein kinases (MAPKAPKs).
Averaged differential expression for the discovery of biomarkers in the blood of patients with prostate cancer.
Hwang et al., Detroit, United States. In Plos One, 2011
A more than 2-fold higher level of RNF19A mRNA in the blood of patients with prostate cancer than in healthy controls makes it an early diagnosis marker for this disease.
Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.
Sobue et al., Nagoya, Japan. In J Neurosci Res, 2010
In addition to causing a decrease in the amount of mutant SOD1 protein in the spinal cord, Dorfin overexpression ameliorated neurological phenotypes and motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis.
Cooperative exonization of MaLR and AluJo elements contributed an alternative promoter and novel splice variants of RNF19.
Kim et al., Pusan, South Korea. In Gene, 2008
Findings suggest that RNF19 has acquired a new promoter and alternative exons via continuous retrotransposition.
Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
Sobue et al., Nagoya, Japan. In J Biol Chem, 2007
Dorfin ubiquitylated mutant SOD1 by recognizing the Cys(6)- and Cys(111)-disulfide cross-linked form and targeted it for proteasomal degradation
Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.
Sobue et al., Nagoya, Japan. In Neurobiol Dis, 2007
Dorfin-CHIP(L) rescued neuronal cells from mutant SOD1-associated toxicity and reduced the aggresome formation induced by mutant SOD1 more effectively than did Dorfin(WT).
More papers using p38 antibodies
Uncaria rhynchophylla induces heme oxygenase-1 as a cytoprotective effect in RAW 264.7 macrophages.
Pal Soumitro, In PLoS ONE, 2009
... used; anti-Nrf2 (Santa Cruz Biotechnology, Santa Cruz, CA), anti-Lamin B (Santa Cruz), anti-HO-1 (Epitomics, Burlingame, CA), anti-phospho-p38 (Cell Signaling Technology, Beverly, MA), anti-phospho-PKC-δ ...
Identification of calcineurin regulated phosphorylation sites on CRHSP-24
Kumar Ujendra et al., In Journal of Molecular Signaling, 2008
... Polyclonal antibodies for total and phospho-ERK1/2 (phosphorylation site-Thr202/Tyr204) and p38 (phosphorylation site- Thr180/Tyr182) were obtained from Cell Signaling Technology, Danvers, MA ...
Adipocytes impair leukemia treatment in mice
Heisterkamp Nora et al., In Oncoimmunology, 2008
... We used Triciribine as Akt inhibitor, SP600125 as JNK inhibitor, and CAY10571 as p38 inhibitor (Cayman Chemicals cat no 10010237, ...
Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met
Cho Sung-Dae et al., In Journal of Clinical Biochemistry and Nutrition, 2008
... The antibodies for phosphor-p38 and total p38 were supplied by Cell Signaling Technology (Beverly, MA) ...
The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells.
Dryer Stuart E., In PLoS ONE, 2008
... Anti-cleaved caspase3, anti-β-Actin, anti-phospho-P44/42 MAP Kinase, anti-P44/42 MAP Kinase, anti-SAPK/JNK, anti-phospho-SAPK/JNK, anti-p38MAP Kinase and anti-phospho-p38 MAP Kinase were from Cell Signaling Technology.Inc (CST, Danvers, Mass, ...
Membrane protein location-dependent regulation by PI3K (III) and rabenosyn-5 in Drosophila wing cells.
Holowka David, In PLoS ONE, 2008
... Antibodies against ERK1/2, PKC (pan), C-Raf, p38, FLAG-tag and HA-tag were from Santa Cruz Biotechnology (Santa Cruz, CA) ...
Interleukin-1 receptor-associated kinase (IRAK) -1-mediated NF-kappaB activation requires cytosolic and nuclear activity.
Kreindler James L., In PLoS ONE, 2007
... Antibodies specific for phosphorylated ERK, phosphorylated-p38, total p38, and IκB-α were from Cell Signaling.
Expression of p21(waf1/cip1), p27 (kip1), p63 and androgen receptor in low and high Gleason score prostate cancer
Kumar Ujendra et al., In Journal of Molecular Signaling, 2007
... Rabbit polyclonal antibodies for total and phospho-ERK1/2 and p38 were obtained from Cell Signaling Technology, Danvers, MA, USA ...
Thrombospondin-1 enhances human thyroid carcinoma cell invasion through urokinase activity.
Hooker Bill, In PLoS ONE, 2007
... (9102), anti-SAPK/JNK (9252), anti-Akt (9272), anti-p38 (9212), anti-Src (32G6), anti-phospho-ERK-1/2 (9101), anti-phospho-SAPK/JNK (9251), anti-phospho-Akt (9271), anti-phospho-p38 (9211), HRP-conjugated anti-rabbit (7074) and specific MEK-1/2 inhibitor U0126 (9903) were from Cell Signaling Technology (distributed by Ozyme, ...
Timing differences of signaling response in neuron cultures activated by glutamate analogue or free radicals
Jiang Jing Hua et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... Primary antibodies specific for p-JNK, JNK, AKT, p-ERK, ERK, p-p38, and p38 were obtained from Cell Signaling Technology (San Francisco, Calif, ...
Novel role of protein disulfide isomerase in the regulation of NADPH oxidase activity: pathophysiological implications in vascular diseases.
Kowaltowski Alicia J., In PLoS ONE, 2007
... Assay Designs/Stressgen (Ann Arbor, MI); CHOP/GADD153 from Thermo Scientific (Golden, CO); Akt, phospho-Akt, p38 and phospho-p38 from Cell Signaling Technology (Danvers, MA); ubiquitin ...
Apoptosis signal-regulating kinase 1 in stress and immune response
Shi Xianglin et al., In Chemical Research in Toxicology, 2007
... Ser473 phosphorylation, phospho-ASK1 specific for Thr838 phosphorylation, phospho-ASK1 specific for Ser83 phosphorylation, ASK1, phospho-p38, and p38 were purchased from Cell Signaling.
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner.
Combs Colin, In PLoS ONE, 2006
... The phospho-JNK and phospho-p38 antibodies (Cell Signaling) were both used at ...
The effect of bovine serum albumin on the membrane potential and reactive oxygen species generation in succinate-supported isolated brain mitochondria.
Combs Colin, In PLoS ONE, 2006
... (sheep, San Diego, CA), to p-p38, pJNK, and pErk MAP kinases were from Santa Cruz Biotechnology (rabbit 1∶1000, Santa Cruz, ...
Inhibition of breast tumor growth and angiogenesis by a medicinal herb: Ocimum gratissimum
Kao Shao-Hsuan et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2006
... caspase-3, caspase-8, caspase-9, apaf-1, Bak, Bcl-2, phosphorylated-ERK1/2 (p-ERK1/2), ERK1/2, phosphorylated-JNK (p-JNK), JNK, phosphorylated-p38 (p-p38), and p38 were purchased from Cell Signaling Technologies (Beverly, MA) ...
RGS18 Acts as a Negative Regulator of Osteoclastogenesis by Modulating Acid-Sensing OGR1/NFAT Signaling Pathway.
Aziz Syed A., In PLoS ONE, 2006
... Anti-phospho-ERK, anti-ERK, anti-phospho-p38, anti-p38 were from Cell Signaling Technology (Beverly, MA) ...
p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation
Tsukita Sachiko et al., In The Journal of Cell Biology, 2005
... pAb, rabbit anti-Trio pAb, rabbit anti-Tbx3 pAb, anti–lamin B pAb (Santa Cruz Biotechnology, Inc.), anti-p38, anti–phospho p38 (Cell Signaling Technology), rabbit anti–claudin-3 pAb ...
Hydrogen sulfide prevents apoptosis of human PMN via inhibition of p38MAPK and caspase3.
Linden Rafael, In PLoS ONE, 2005
... Monoclonal anti-CBS antibody, anti-Cleaved-caspase-3 antibody, anti-p38 antibody, anti-p-p38 antibody, SP600125 and SB203580 were purchased from Cell Signaling Technology (Boston, MA, USA) ...
CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo
O’Donnell Robert T. et al., In Cancer Immunology, Immunotherapy, 2005
... IgG (H + L) Texas Red conjugate (Rockland Immunochemicals; Gilbertsville, PA), anti-phospho-JNK, anti-JNK, anti-phospho-ERK1/2, anti-ERK1/2, anti-phospho-p38, and anti-p38 antibodies (Cell Signaling Technology, Danvers, MA), anti-mouse ...
Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs
Plevin Robin et al., In Cellular Signalling, 2005
... Anti-IκBα, anti-JNK and p38 MAP kinase antibodies were obtained from Santa Cruz Biotechnology (CA, USA) ...
Pathways Regulating Cytosolic Phospholipase A2 Activation and Eicosanoid Production in Macrophages by Candida albicans*
Leslie Christina C. et al., In The Journal of Biological Chemistry, 2005
... Antibodies to phosphorylated ERKs, p38, and cPLA2α (Ser-505) were obtained from Cell Signaling Technology, Inc ...
Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
Finkelstein David I., In PLoS ONE, 2005
... were used for Western Blot: JNK1, phospho-JNK (Thr183/Tyr185), c-Jun, phospho-c-Jun (Ser63), ERK1/2, phospho-ERK1/2 (Thr202/Tyr204), p38, phospho-p38 (Thr180/Tyr182), that were provided from Santa Cruz Biotechnology, (Santa Cruz, CA, USA) ...
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
Chen Chin-Tin et al., In Molecular Cancer, 2005
... Antibodies to phosphorylated ERK, p38, and AMPK or total ERK, JNK and p38 were purchased from Cell Signaling Technology (Danvers, MA, USA) ...
Smad4 is required for the normal organization of the cartilage growth plate
Glimcher Laurie H et al., In The EMBO Journal, 2004
... used were anti-TAK1 (Millipore); anti-HA, anti-c-Myc, and anti-BMPR-1A (Santa Cruz); anti-Smad2, anti-phospho-Smad1/5/8, anti-phospho-Smad2 (S465/467), and anti-phospho-p38 (Cell Signaling); anti-Smad1 (Invitrogen); anti-Flag (M2, ...
A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.
Bridger Joanna Mary, In PLoS ONE, 2004
... The rabbit polyclonal and mouse monoclonal antibodies raised against Erk, phospho-Erk, p38 and phospho-p38 were obtained from Cell Signaling Technology Inc ...
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
Borthwick Lee A. et al., In The American Journal of Pathology, 2004
... (2370; Cell Signaling), phospho-IKKα/β (2681; Cell Signaling), JNK-1/2 (9252; Cell Signaling), phospho-JNK-1/2 (4668; Cell Signaling), p38 (sc-7149; Santa Cruz Biotechnology), phospho-p38 (ab4822; Abcam), ERK-1/2 ...
Ral GTPases regulate neurite branching through GAP-43 and the exocyst complex
Hall Alan et al., In The Journal of Cell Biology, 2003
... mouse anti-myc (clone 9E10), rabbit anti-myc (Research Diagnostics, Inc.), mouse anti–βIII tubulin (Sigma-Aldrich), and rabbit anti-p38 (Santa Cruz Biotechnology, Inc.) ...
Prostaglandin E2 enhances pancreatic cancer invasiveness through an ETS1-dependent induction of matrix metalloproteinase-2
Fang Deyu et al., In Arthritis Research & Therapy, 2003
... Antibodies against JNK1, Erk, and p38 were purchased from Promega Corporation (Madison, WI, USA) ...
Transcription factor GATA-5 selectively up-regulates mucin gene expression
Song YinXue et al., In BMC Cancer, 2003
... Antibodies for Nuclear factor-κB (NF-κB) p65, extracellular signal-regulated kinase (ERK1/2), JNK, P38 and phospho-ERK1/2, JNK, P38 were obtained from Cell Signaling Technology (Beverly, MA), aspirin, ...
Coordinate signaling by Src and p38 kinases in the induction of cortical cataracts
Fisher P. B. et al., In Oncogene, 2003
... (Covance Research Products, Denver, PA), anti-MDA-9/syntenin polyclonal antibody (Alpha-Diagnostic International, San Antonio, TX), anti-p38 and anti-phospho-p38 (Cell Signaling, Beverly, MA), SB103580, PP2 ...
Among circulating hematopoietic cells, BCLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis
Kooijman R. et al., In Cellular and Molecular Life Sciences, 2003
... Rabbit antibodies against p38 were from Santa Cruz Biotechnology (Santa Cruz, Calif.) ...
The serine/threonine kinase Akt promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase
Schneider David, In PLoS Pathogens, 2003
... Antibodies specific for phospho-Erk, phospho-JNK, phospho-SHIP, phospho-Akt, and phospho-p38 were purchased from Cell Signaling Technology (Beverly, Massachusetts, United ...
Inhibition of chondrocyte apoptosis in vivo following acute osteochondral injury
Bae Sang-cheol et al., In Arthritis Research & Therapy, 2002
... Anti-phospho extracellular signal-regulated protein kinase (ERK) 1/2, anti-phospho-p38, anti-ERK 1/2, and anti-p38 were purchased from New England Biolabs (Beverly, MA, USA), anti-Bcl-2 ...
Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis
Grimm Stefan et al., In Cell Death and Differentiation, 2002
... Anti-TRAF2 (H-249), -TRAF2 (F4), -c-IAP2 (H85), -TNFR1 (H5), -RIP1 (H207), -p38 (N20) and IκB (C-21) antibodies were from Santa Cruz Biotechnology (Tebu-Bio, UK) ...
More than folding: localized functions of cytosolic chaperones.
Possenti Roberta et al., In Cell Biology International Reports, 2002
... the phosphorylated kinases: ERK (p-ERK), PKC (p-PKC), AMPK (p-AMPK), Akt (p-Akt), JNK (p-JNK) and p38 (p-p38) were from Cell Signaling Technologies ...
Modulation of neutrophil function by the tripeptide feG
Kunapuli Satya P. et al., In Purinergic Signalling, 2002
... phospho-p44/42 MAP kinase (Thr202/Tyr204), anti-p44/442 MAP kinase, anti phospho-p38 MAP kinase (Thr180/Tyr182) antibodies, and anti p38 MAP kinase were from Cell Signaling Technology (Beverly, Massachusetts, USA).
A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid–induced neuronal differentiation
Lee Angel W.-M. et al., In The Journal of Cell Biology, 2001
... Cruz Biotechnology, Inc.); PY (4G10), and bFM-1 (UBI); pAKT, pGSK3, pERK, active caspase-3 antibodies, and α-p-p38 antibody-conjugated beads (Cell Signaling); FLAG (M2) and GFAP ...
Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-β
Xu Lieming et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 2001
... Smad4 polyclonal antibody, p-p38 monoclonal antibody, p38, p-MEK and MEK monoclonal antibody were purchased from Cell Signaling Technology (Beverly, MA, USA); ...
Cbl-b Positively Regulates Btk-mediated Activation of Phospholipase C-γ2 in B Cells
Yamamoto Tadashi et al., In The Journal of Experimental Medicine, 2000
... Abs were purchased: anti–Cbl-b (C-20), anti–Cbl-b (G-1), anti–mouse PLC-γ2, anti-Rap1, anti–extracellular signal-regulated kinase (ERK)2, and anti-p38 (Santa Cruz Biotechnology, Inc.); anti-JNK1 (BD PharMingen), ...
Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation
Chen Cheng-Nan et al., In Journal of Biomedical Science, 2000
... Rabbit polyclonal antibodies against p38 and mouse monoclonal phospho-p38 antibody were purchased from Cell Signaling Technology (Beverly, MA) ...
Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems.
Damania Blossom, In PLoS Pathogens, 2000
... We used the following antibodies: Monoclonal antibodies against IKKβ (2C8, Cell Signaling), phopho-p38 (3D7, Cell Signaling), Flag (M2, Sigma), β ...
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
Chatziantoniou Christos, In PLoS ONE, 1999
... Anti-phospho-p38 antibodies and anti-p38 antibodies were purchased from Cell Signaling Technology (USA) ...
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
Rodriguez-Sosa Miriam et al., In International Journal of Biological Sciences, 1999
... A primary rabbit anti-mouse antibody against ERK or p38 (both from Biovision, San Diego, CA, USA) ...
Organization and regulation of mitogen-activated protein kinase signaling pathways.
Liou Gregory I. et al., In Molecular Vision, 1998
... Antibodies against glial fibrillar acidic protein (GFAP), phospho-tyrosine, phospho-ERK (pERK), ERK, phospho-P38 (pP38) and P38 were purchased from Cell Signaling (Beverly, MA) ...
p38 mitogen-activated protein kinase inhibitors-mechanisms and therapeutic potentials
Moilanen Eeva et al., In Mediators of Inflammation, 1998
... were from Santa Cruz Biotechnology, Inc, (Santa Cruz, Calif); and rabbit polyclonal phospho-JNK, phospho-Erk1/2, Erk1/2, phospho-p38, and p38 antibodies were from Cell Signaling Technology, Inc, (Beverly, Mass) ...
Mechanical force-induced signal transduction in lung cells
Ludwig Mara S et al., In Respiratory Research, 1998
... The antibodies: rabbit anti-phosphorylated ERK1/ERK2, anti-phosphorylated p38, anti-phosphorylated JNK, anti-total ERK1/ERK2 and anti-total p38 came from Cell Signaling Technology (Beverly, MA, USA), ...
Essential role of nuclear factor B in the induction of eosinophilia in allergic airway inflammation
Kim Sun-Young et al., In Clinical and Molecular Allergy : CMA, 1997
... BD Biosciences, the protein assay kit was from Bio-Rad Laboratories, anti-pERK, anti-ERK, anti-pJNK, anti-JNK, and anti-p-p38 were from Cell Signaling Technology, anti-p65 and anti-p38 ...
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor
Feng Gen-Sheng et al., In The Journal of Experimental Medicine, 1997
... Antibodies specific for phospho-Erk1/2, phospho-Jnk, or phospho-p38 MAP kinase were purchased from New England Biolabs, Inc ...
Nuclear Factor of Activated T Cells Balances Angiogenesis Activation and Inhibition
Volpert Olga V. et al., In The Journal of Experimental Medicine, 1997
... A mouse JNK1 mAb (BD Biosciences), rabbit anti-JNK/SAPK1 pAb (Upstate Biotechnology), anti-Erk1/2 (Promega), and anti-p38 (Santa Cruz Biotechnology, Inc.) were used to ...
The PSD95–nNOS interface
Courtney Michael J. et al., In The Journal of Cell Biology, 1996
... Mouse anti-GFP (CLONTECH Laboratories, Inc.), rabbit anti–phospho-p38 (New England Biolabs, Inc.) and mouse anti–pan-p38 ...
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
Sundler Roger et al., In Journal of Inflammation (London, England), 1995
... Antibodies against p-ERK, p-p38 and pAkt (Thr308) were from New England Biolabs (Beverly, MA, USA) ...
Mitochondrial control of nuclear apoptosis
Lee Hong-Zin et al., In Evidence-based Complementary and Alternative Medicine : eCAM, 1995
... Ras, Rho, Cdc42, ERK, JNK, p38, PKCα, PKCδ, and PKCε antibodies were purchased from BD Biosciences (San Diego, CA, USA) ...
An essential role for the MAL protein in targeting Lck to the plasma membrane of human T lymphocytes
Alonso Miguel A. et al., In The Journal of Experimental Medicine, 1991
... Antibodies to total or phosphorylated Erk and p38 used for immunoblotting were obtained from Promega and Santa Cruz Biotechnology, Inc., respectively ...
Bowman lecture. The conquest of cataract: a global challenge.
Liu Ping et al., In Molecular Vision, 1984
... Anti-JNK, anti-phosphorylation of JNK (p-JNK), anti-p38 and anti-phosphorylation of p38 (p-p38) were purchased from Santa Cruz Biotechnology Inc ...
Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose
Johannes Ludger, In PLoS ONE, 1983
... used: rabbit anti-EGFR antibody (Cell Signaling Technology); rabbit anti-COX IV antibody (Cell Signaling Technology); rabbit anti-p38 antibody (Cell Signaling Technology); rabbit anti-phospho-p38 MAPK ...
The nucleotide sequence of the chick cytoplasmic β-actin gene
Kurosaki Tomohiro et al., In The Journal of Experimental Medicine, 1982
... The following Abs were purchased: anti-ERK2 and anti-p38 from Santa Cruz Biotechnology, Inc. ...
Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.
Steinhardt Richard, In PLoS ONE, 1978
... Louis, MO); polyclonal antibodies against phospho-p38 and p38 were from Cell Signaling (Beverly, MA); fluorescently labeled ...
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