Protecting against ischemic stroke in rats by HSP 20-mediated exercise.
Taipei, Taiwan. In Eur J Clin Invest, Nov 2015
METHOD: Adult male Sprague-Dawley rats (288 in number) were used to investigate the contribution of HSP20-containing neurons and HSP20-containing glial cells in the exercise-mediated neuroprotection in the stroke condition using middle cerebral artery occlusion.
Emerging targets for novel therapy of asthma.
Mobile, United States. In Curr Opin Pharmacol, 2013
The cAMP/PKA pathway continues to be a promising drug target with the emergence of new PDE inhibitors and a novel PKA target protein, HSP20, which mediates smooth muscle relaxation via actin depolymerization.
Large potentials of small heat shock proteins.
Moscow, Russia. In Physiol Rev, 2011
HSPB6 (HSP20) also possesses chaperone-like activity, is involved in regulation of smooth muscle contraction, has pronounced cardioprotective activity, and seems to participate in insulin-dependent regulation of muscle metabolism.
The emerging role of HSP20 as a multifunctional protective agent.
Glasgow, United Kingdom. In Cell Signal, 2011
Recently, one member of the sHSP family, HSP20 (HspB6), has been shown to be highly effective as a protective mediator against a number of debilitating pathological conditions, including cardiac hypertrophy and Alzheimer's disease.
Crystal structure of Arp2/3 complex.
Los Angeles, United States. In Science, 2001
Subunits ARPC2 p34 and ARPC4 p20 in the core of the complex associate through long carboxyl-terminal alpha helices and have similarly folded amino-terminal alpha/beta domains.