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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Exosome component 1

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, ETV6, Inv
Papers on p13
Comparison of linear motion perception thresholds in vestibular migraine and Menière's disease.
MacNeilage et al., München, Germany. In Eur Arch Otorhinolaryngol, Feb 2016
The cVEMP p13 latencies differed significantly across groups being lowest in VM.
Good response to long-term therapy with growth hormone in a patient with 9p trisomy syndrome: A case report and review of the literature.
Jorge et al., São Paulo, Brazil. In Am J Med Genet A, Jan 2016
SNP array data indicated absence of mosaicism [arr 9p24.3-p13.1 (203,861-38,787,480) x3].
Genotype-phenotype correlation of 16p13.3 terminal duplication and 22q13.33 deletion: Natural history of a patient and review of the literature.
Gil-da-Silva-Lopes et al., Campinas, Brazil. In Am J Med Genet A, Jan 2016
After genomic array and FISH analysis, the karyotype was 46,XX,ins(22;16)(q13;p13.2p13.3).
Molecular pathogenesis of lymphomas of mucosa-associated lymphoid tissue-from (auto)antigen driven selection to the activation of NF-κB signaling.
Liu et al., Shanghai, China. In Sci China Life Sci, Dec 2015
A number of genetic alterations have been identified in MALT lymphoma, and among them are important translocations, such as t(11;18)(q21;q21), t(1;14)(p22;q32), t(14;18)(q32;q21) and t(3;14)(p13;q32).
Identification of an Alu-repeat-mediated deletion of OPTN upstream region in a patient with a complex ocular phenotype.
Semina et al., Milwaukee, United States. In Mol Genet Genomic Med, Nov 2015
Comparison of transcriptional activation capability of the 3 kb normal and the rearranged del(10)(p13) OPTN promoter sequences demonstrated a statistically significant decrease for the deleted allele; sequence analysis of the entire deleted region identified multiple conserved elements with possible cis-regulatory activity.
[Abnormal Karyotypes Involving 1q21 and 12p13 and Their Clinical Significance].
Sun et al., Beijing, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, Oct 2015
Among them, the one abnormal karyotype translocation, t (1;12) (q21; p13) is a rare karyotype change.
The segregation of different submicroscopic imbalances underlying the clinical variability associated with a familial karyotypically balanced translocation.
Vianna-Morgante et al., São Paulo, Brazil. In Mol Cytogenet, 2014
CASE PRESENTATION: We report on a karyotypically balanced translocation t(2;22)(p13;q12.2) associated with variable learning disabilities, and craniofacial and hand dysmorphisms, detected in six individuals in a three-generation family.
Paediatric acute myeloid leukaemia with the t(7;12)(q36;p13) rearrangement: a review of the biological and clinical management aspects.
Saccone et al., Catania, Italy. In Biomark Res, 2014
It has been estimated that approximately one third of infants with acute myeloid leukaemia harbour the t(7;12)(q36;p13) rearrangement in their leukaemic blasts.
Ocular and Cervical Vestibular Evoked Myogenic Potentials (VEMPs) in healthy volunteers: the intra-, interobserver, and the test re-test reliability.
Verhagen et al., In J Vestib Res, 2014
The test re-test reliability of the raw p13n23 peak-to-peak amplitudes of the cervical VEMPs is excellent (ICC: 0.76, 0.87) and the p13 latencies show a good reliability (ICC: 0.56, 0.73).
Test-retest reliability of binaural simultaneous cervical vestibular evoked myogenic potential recording.
Suh et al., Seoul, South Korea. In J Vestib Res, 2014
RESULTS: Both p13 and n23 latencies did not show a statistically significant difference between the two cVEMP recording methods.
Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician.
Flynn et al., In J Clin Oncol, 2014
RESULTS: Current strategies separate patients based on age or functional status as well as genetics [presence or absence of del(17)(p13.1)].
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.
Downing et al., Memphis, United States. In Cancer Cell, 2012
Our analysis identified a cryptic chromosome 16 inversion (inv(16)(p13.3q24.3)) in 27% of pediatric cases, which encodes a CBFA2T3-GLIS2 fusion protein.
Yeast RNA viruses as indicators of exosome activity: human exosome hCsl4p participates in RNA degradation in Saccharomyces cerevisiae'.
Esteban et al., Salamanca, Spain. In Yeast, 2011
Human exosome hCsl4p participates in RNA degradation.
Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.
van Dongen et al., Rotterdam, Netherlands. In J Clin Oncol, 2011
In one patient with a second T-ALL, SNP analysis revealed a germline del(11)(p12;p13), a known recurrent aberration in T-ALL.
Genetic loci influencing kidney function and chronic kidney disease.
Kooner et al., London, United Kingdom. In Nat Genet, 2010
Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)).
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.
Orkin et al., Boston, United States. In Cancer Cell, 2007
To better understand the cellular origin of breast cancer, we developed a mouse model that recapitulates expression of the ETV6-NTRK3 (EN) fusion oncoprotein, the product of the t(12;15)(p13;q25) translocation characteristic of human secretory breast carcinoma.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Pruijn et al., Nijmegen, Netherlands. In J Mol Biol, 2002
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Protein-protein interactions of hCsl4p with other human exosome subunits.
Pruijn et al., Nijmegen, Netherlands. In J Mol Biol, 2002
association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p and hRrp46p
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