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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Family with sequence similarity 3, member B

ORF9, FAM3B, PANDER, pancreatic derived factor
Top mentioned proteins: ACID, Insulin, HAD, CAN, Orf
Papers on ORF9
Characterization of MDAΦ, a temperate filamentous bacteriophage of Neisseria meningitidis.
Bille et al., Paris, France. In Microbiology, Dec 2015
At least three genes of the prophage are necessary for the formation of the replicative cytoplasmic form (orf1, orf2 and orf9).
Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.
Koelle et al., Atlanta, United States. In J Infect Dis, Nov 2015
The immunogenicity of ORF9 and ORF18 were confirmed using peptides, defining a large number of discrete CD4 T-cell epitopes.
Identification and characterization of cis- and trans-acting elements involved in prophage induction in Streptococcus thermophilus J34.
Heller et al., Kiel, Germany. In Mol Microbiol, Oct 2015
A polycistronic transcript comprising genes coh (encoding Cro homolog), ant (encoding putative antirepressor), orf7, orf8 and orf9 was only detected in the lytic state.
Hepatic nutrient and hormonal regulation of the PANcreatic-DERived factor (PANDER) promoter.
Burkhardt et al., Tampa, United States. In Mol Cell Endocrinol, Oct 2015
PANcreatic-DERived factor (PANDER, FAM3B) has been shown to regulate glycemic levels via interactions with both pancreatic islets and the liver.
Protective effects of aerobic swimming training on high-fat diet induced nonalcoholic fatty liver disease: regulation of lipid metabolism via PANDER-AKT pathway.
Liu et al., Jinzhou, China. In Biochem Biophys Res Commun, Apr 2015
PANDER and FOXO1 expressions increased, whereas AKT expression decreased in the HFD group.
Deletion of the ORF9p acidic cluster impairs the nuclear egress of varicella-zoster virus capsids.
Sadzot-Delvaux et al., Liège, Belgium. In J Virol, Feb 2015
The protein encoded by ORF9 is essential for varicella-zoster virus (VZV) replication.
Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer.
Yu et al., Hong Kong, Hong Kong. In Gastroenterology, 2014
Integrated epigenome and transcriptome analyses identified 216 genes transcriptionally down-regulated by EBV-associated hypermethylation; methylation of ACSS1, FAM3B, IHH, and TRABD increased significantly in EBV-positive tumors.
Effector and Central Memory Poly-Functional CD4(+) and CD8(+) T Cells are Boosted upon ZOSTAVAX(®) Vaccination.
Vora et al., United States. In Front Immunol, 2014
We identified a novel poly-functional ORF9-specific CD8(+) T cell population in 62% of the subjects, and these were boosted upon vaccination.
Role of pro-inflammatory cytokines of pancreatic islets and prospects of elaboration of new methods for the diabetes treatment.
Cieślak et al., Toruń, Poland. In Acta Biochim Pol, 2014
Pro-inflammatory cytokines such as interleukin 1β (IL-1β), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ), as well as recently discovered pancreatic derived factor PANDER are involved in the apoptosis of pancreatic β-cells.
F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression.
Cao et al., Tampa, United States. In Plos One, 2014
OBJECTIVE: Pancreatic-derived factor (PANDER, also named as FAM3B) is secreted by pancreatic α and β cells.
Enhanced glucose tolerance in pancreatic-derived factor (PANDER) knockout C57BL/6 mice.
Burkhardt et al., Tampa, United States. In Dis Model Mech, 2014
Pancreatic-derived factor (PANDER; also known as FAM3B) is a uniquely structured protein strongly expressed within and secreted from the endocrine pancreas.
Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates.
Sadzot-Delvaux et al., Liège, Belgium. In Virology, 2014
We created a recombinant VZV expressing ORF23 (homologous to HSV-1 VP26) fused to the eGFP and dually fluorescent viruses with a tegument protein additionally fused to a red tag (ORF9, ORF21 and ORF22 corresponding to HSV-1 UL49, UL37 and UL36).
Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease.
Guan et al., Beijing, China. In J Gastroenterol Hepatol, 2013
The family with sequence similarity 3 (FAM3) gene family is a cytokine-like gene family with four members designated FAM3A, FAM3B, FAM3C, and FAM3D, respectively.
Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4.
Yang et al., Fuzhou, China. In Biochem Biophys Res Commun, 2012
these results demonstrated that the JNK-mediated signaling mechanism of palmitic acid -induced beta-cell apoptosis involves up-regulated expression of PANDER and activation of caspase-3.
Role of pancreatic-derived factor in type 2 diabetes: evidence from pancreatic β cells and liver.
Yang et al., Beijing, China. In Nutr Rev, 2012
Pancreatic-derived factor (PANDER) is a cytokine-like protein that is highly expressed in pancreatic islets.
Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic β-cells by MCP-1 (CCL2).
Le et al., Shanghai, China. In Mol Cell Endocrinol, 2011
Data suggest a new link between the endocrine and immune systems and provide useful information for further investigating the physiological functions of PANDER and its involvement in inflammation-related pancreatic disorders.
PANcreatic-DERived factor: novel hormone PANDERing to glucose regulation.
Burkhardt et al., Philadelphia, United States. In Febs Lett, 2011
PANcreatic-DERived factor (PANDER, FAM3B) is a member of the FAM3 family of cytokine molecules that were initially described in 2002.
[Effects of glucagon-like peptide-1 on the free fatty acid-induced expression of pancreatic derived factor in cultured β-TC3 cell line].
Li et al., Guangzhou, China. In Zhonghua Yi Xue Za Zhi, 2011
Palmitic acid induces the expression of PANDER and the apoptosis of beta-TC3 cells while glucagon-like peptide-1 counteracts the above effects through an activation of Akt signaling.
Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway.
Guan et al., Beijing, China. In Hepatology, 2011
PANDER promotes lipogenesis and compromises insulin signaling in the liver by increasing FOXO1 activity.
PANDER KO mice on high-fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia.
Burkhardt et al., Philadelphia, United States. In Febs Lett, 2011
Findings further indicate PANDER impacts glycemic levels and may represent a potential but complicated therapeutic target.
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