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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Olfactory marker protein

OMP, Olfactory Marker Protein
Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, SDSL, fibrillin-1
Papers using OMP antibodies
Olfactory marker protein gene: its structure and olfactory neuron-specific expression in transgenic mice
Dulac Catherine et al., In Nature, 1988
... Olfactory marker protein gene: its structure and olfactory neuron-specific expression in transgenic mice ...
Papers on OMP
RpoE is a Putative Antibiotic Resistance Regulator of Salmonella enteric Serovar Typhi.
Du et al., Suzhou, China. In Curr Microbiol, Feb 2016
Our results suggest RpoE is a potential antimicrobial regulator in S. Typhi, controlling both the down regulation of the OMP genes and up-regulating the efflux system.
The activity of Escherichia coli chaperone SurA is regulated by conformational changes involving a parvulin domain.
Silhavy et al., Princeton, United States. In J Bacteriol, Feb 2016
When combined with mutations in the ß-barrel assembly machine (BAM), SurA mutations resulting in deletion of the second parvulin domain (P2) inhibit OMP assembly, suggesting that P2 is involved in the regulation of SurA.
Chronic anosmia induces depressive behavior and reduced anxiety via dysregulation of glucocorticoid receptor and corticotropin-releasing hormone in a mouse model.
Kim et al., Seoul, South Korea. In Rhinology, Jan 2016
H&E staining, OMP staining, and potato chip finding test were performed to confirm olfactory loss.
Influence of heat-labile serum components in the presence of OmpA on the outer membrane of Salmonella gallinarum.
Verdugo-Rodríguez et al., San Luis Potosí, Mexico. In Arch Microbiol, Dec 2015
Being a Gram-negative bacteria, its outer membrane proteins (OMP) can be regulated by different microenvironments.
Outer membrane protein biogenesis in Gram-negative bacteria.
Buchanan et al., Bethesda, United States. In Philos Trans R Soc Lond B Biol Sci, Nov 2015
However, the past decade has witnessed significant progress towards unravelling the pathways and mechanisms necessary for moulding a nascent polypeptide into a functional OMP within the OM.
Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.
Whalen et al., Urbana, United States. In Biochim Biophys Acta, Aug 2015
We provide an introduction to SSNs, a description of EFI-EST, and a demonstration of the use of EFI-EST to explore sequence-function space in the OMP decarboxylase superfamily (PF00215).
Two stress sensor proteins for the expression of sigmaE regulon: DegS and RseB.
Kim, Kyŏngsan, South Korea. In J Microbiol, May 2015
For the induction of sigmaEstress response, DegS and RseB recognize the states of OMP and LPS for outer-membrane biogenesis.
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28.
Jimeno et al., United States. In Pharmacol Ther, Feb 2015
OMP-54F28 is a fusion protein that combines the cysteine-rich domain of frizzled family receptor 8 (Fzd8) with the immunoglobulin Fc domain that competes with the native Fzd8 receptor for its ligands and antagonizes Wnt signaling.
Gene Expression Profiles of Main Olfactory Epithelium in Adenylyl Cyclase 3 Knockout Mice.
Ma et al., Baoding, China. In Int J Mol Sci, 2014
Quantitative RT-PCR verification of the differentially expressed epigenetic regulation related genes, olfactory receptors, ion transporter related genes, neuron development and differentiation related genes, lipid metabolism and membrane protein transport etc. related genes showed that P75NTR, Hinfp, Gadd45b, and Tet3 were significantly up-regulated, while Olfr370, Olfr1414, Olfr1208, Golf, Faim2, Tsg101, Mapk10, Actl6b, H2BE, ATF5, Kirrrel2, OMP, Drd2 etc. were significantly down-regulated.
Mechanism to control the cell lysis and the cell survival strategy in stationary phase under heat stress.
Noor, Dhaka, Bangladesh. In Springerplus, 2014
Heat stress is usually sensed through the misfolded outer membrane porin (OMP) precursors in the periplasm, resulting in the activation of σ(E) (encoded by rpoE), which binds to RNA polymerase to start the transcription of genes required for responding against the heat stress signal.
Olfactory marker protein is critical for functional maturation of olfactory sensory neurons and development of mother preference.
Ma et al., Philadelphia, United States. In J Neurosci, 2011
Olfactory sensory neurons undergo an olfactory marker protein-dependent functional maturation process that coincides with early development of the smell function, which is essential for pups to form preference for their mother.
Ca extrusion by NCX is compromised in olfactory sensory neurons of OMP mice.
Margolis et al., Baltimore, United States. In Plos One, 2008
OMP can influence CaM efficacy and thus alters NCX activity by a series of protein-protein interactions
Olfactory marker protein modulates the cAMP kinetics of the odour-induced response in cilia of mouse olfactory receptor neurons.
Margolis et al., Baltimore, United States. In J Physiol, 2008
These observations explain the deficits in odour detection threshold and odour quality discrimination seen in the OMP(-/-) mice
Allosteric activation of DegS, a stress sensor PDZ protease.
Sauer et al., Cambridge, United States. In Cell, 2007
OMP binding shifts the equilibrium from a nonfunctional state, in which the active sites are unreactive, to the functional proteolytic conformation.
Allosteric activation of a bacterial stress sensor.
Shi et al., Beijing, China. In Cell, 2007
In Gram-negative bacteria, envelope stress signals such as unfolded outer membrane proteins (OMP) activate the periplasmic protease DegS.
Backbone dynamics of the olfactory marker protein as studied by 15N NMR relaxation measurements.
Margolis et al., Baltimore, United States. In Biochemistry, 2005
Dynamic properties of alpha 1, loop 1, and the omega loop (loop 3) of OMP indicate that these three regions of OMP are all dynamic in solution on multiple time scales
Olfactory marker protein modulates primary olfactory axon overshooting in the olfactory bulb.
Key et al., Brisbane, Australia. In J Comp Neurol, 2005
Axons overshoot their target layer and grow into the external plexiform layer in OMP null mice. However, in the absence of OMP, overshooting axons are more persistent and remain prominent until 5 weeks postnatally, after which their numbers decrease.
OMP peptide signals initiate the envelope-stress response by activating DegS protease via relief of inhibition mediated by its PDZ domain.
Sauer et al., Cambridge, United States. In Cell, 2003
Here, we show that peptides ending with OMP-like C-terminal sequences bind the DegS PDZ domain, activate DegS cleavage of RseA, and induce sigma(E)-dependent transcription.
Catalytic proficiency: the unusual case of OMP decarboxylase.
Wolfenden et al., Madison, United States. In Annu Rev Biochem, 2001
Enzymes are called upon to differ greatly in the difficulty of the tasks that they perform.
Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile.
Perkins et al., Atlanta, United States. In Jama, 1999
INTERVENTION: Participants received 3 doses of outer-membrane protein (OMP) meningococcal vaccine developed in either Cuba or Norway or a control vaccine, with each dose given 2 months apart.
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