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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Olfactomedin 3

Olfm3, Optimedin, Olfactomedin 3, Noelin 3
a Golgi and secreted protein that is involved in eye development and function [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: SET, myocilin, Pax6, HAD, OUT
Papers on Olfm3
Identification of a novel Parkinson's disease locus via stratified genome-wide association study.
Payami et al., Albany, United States. In Bmc Genomics, 2013
It is flanked by S1PR1 and OLFM3 genes, and is 200 kb from a multiple sclerosis susceptibility gene.
microRNA-18b is upregulated in breast cancer and modulates genes involved in cell migration.
López-Camarillo et al., Mexico. In Oncol Rep, 2013
We found that knock-down of miR-18b induced the upregulation of 55 olfactory receptor (OR) genes and nine genes (NLRP7, KLK3, OLFM3, POSTN, MAGED4B, KIR3DL3, CRX, SEMG1 and CEACAM5) with key roles in cell migration and metastasis.
Identification of recently selected mutations driven by artificial selection in hanwoo (korean cattle).
Lee et al., Suwŏn, South Korea. In Asian-australas J Anim Sci, 2013
Five genes (DPH5, OLFM3, S1PR1, LRRN1 and CRBN) were included in this region.
Comprehensive DNA copy number profile and BAC library construction of an Indian individual.
Satyamoorthy et al., India. In Gene, 2012
The library was screened by PCR using SHANK3 (SH3 and multiple ankyrin repeat domains 3) and OLFM3 (olfactomedin 3) specific primers.
Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line.
Clynes et al., Dublin, Ireland. In Exp Cell Res, 2012
This is the first instance of OLFM3 being linked with anoikis resistance in a human cancer cell line
Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins.
Tomarev et al., Bethesda, United States. In Invest Ophthalmol Vis Sci, 2011
Interaction of OLFM2 with olfactomedin 1 (Olfm1), olfactomedin 3 (Olfm3), myocilin, and gliomedin was studied by using co-immunoprecipitation.
Identification of pax6-dependent gene regulatory networks in the mouse lens.
Cvekl et al., New York City, United States. In Plos One, 2008
Differential expression of nine genes implicated in lens development and homeostasis: Cspg2, Igfbp5, Mab21l2, Nrf2f, Olfm3, Spag5, Spock1, Spon1 and Tgfb2, was confirmed by quantitative RT-PCR, with five of these genes: Cspg2, Mab21l2, Olfm3, Spag5 and Tgfb2, identified as candidate direct Pax6 target genes by quantitative chromatin immunoprecipitation (qChIP).
Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision.
Terskikh et al., Lausanne, Switzerland. In Mol Cell Neurosci, 2008
Temporal analysis of the MGE revealed differential expression of unique sets of cell specification and migration genes, with early expression of Hes1, Lhx2, Ctgf and Mdk, and late enrichment of Olfm3, SerpinE2 and Wdr44.
Optimedin induces expression of N-cadherin and stimulates aggregation of NGF-stimulated PC12 cells.
Tomarev et al., Bethesda, United States. In Exp Cell Res, 2007
Optimedin, also known as olfactomedin 3, belongs to a family of olfactomedin domain-containing proteins.
Severe autosomal recessive retinitis pigmentosa maps to chromosome 1p13.3-p21.2 between D1S2896 and D1S457 but outside ABCA4.
Hejtmancik et al., Bethesda, United States. In Hum Genet, 2005
Sequencing the exons and intron-exon boundaries of five candidate genes and six ESTs in this region, OLFM3, GNAI3, LOC126987, FLJ25070, DKFZp586G0123, AV729694, BU662869, BU656110, BU171991, BQ953690, and CA397743, did not identify any causative mutations.
The Optimedin gene is a downstream target of Pax6.
Tomarev et al., Bethesda, United States. In J Biol Chem, 2005
Pax6 regulation of Optimedin in the eye and brain may directly affect multiple developmental processes, including cell migration and axon growth
Bioinformatic approaches for identification and characterization of olfactomedin related genes with a potential role in pathogenesis of ocular disorders.
Ray et al., Calcutta, India. In Mol Vis, 2004
In vitro experiments demonstrated interaction between optimedin and myocilin through the conserved olfactomedin domains of the proteins in rats, and it was speculated that optimedin might have a role in the pathogenesis of ocular disorders.
Optimedin: a novel olfactomedin-related protein that interacts with myocilin.
Tomarev et al., Bethesda, United States. In Hum Mol Genet, 2002
identification of a novel olfactomedin-related gene, named optimedin, located on chromosome 1p21 in humans, expressed in brain and retina; may be a candidate gene for disorders involving the anterior segment of the eye and the retina (optimedin)
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