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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Obg-like ATPase 1

OLA1, Obg-like ATPase 1, PTD004
Top mentioned proteins: ATPase, ACID, BARD1, HAD, CAN
Papers on OLA1
Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3β-inhibitor 2-PP1 positive feedback loop.
Shi et al., Hangzhou, China. In Oncotarget, Jan 2016
UNASSIGNED: OLA1 is an Obg family P-loop NTPase that possesses both GTP- and ATP-hydrolyzing activities.
The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function.
Henderson et al., Sydney, Australia. In Cell Signal, Sep 2015
BARD1 comprises a tandem BRCT domain at the C-terminus, and this sequence has been reported to target BARD1 to distinct subcellular locations such as nuclear DNA breakage sites and the centrosome through binding to regulatory proteins such as HP1 and OLA1, respectively.
OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation.
Shi et al., Houston, United States. In Sci Rep, 2014
This study shows that OLA1, a member of the ancient Obg family of GTPases, is an eIF2-regulatory protein that inhibits protein synthesis and promotes ISR by binding eIF2, hydrolyzing GTP, and interfering with TC formation.
A global investigation of gene deletion strains that affect premature stop codon bypass in yeast, Saccharomyces cerevisiae.
Golshani et al., Ottawa, Canada. In Mol Biosyst, 2014
Three candidate genes, OLA1, BSC2, and YNL040W, were further investigated, and were found to be important for cytoplasmic protein biosynthesis.
Regulation of cell-matrix adhesion by OLA1, the Obg-like ATPase 1.
Shi et al., Houston, United States. In Biochem Biophys Res Commun, 2014
In this study, we explored the role of OLA1, a newly identified member of Obg-like ATPases, in regulating cell adhesion processes.
The BRCA1/BARD1-interacting protein OLA1 functions in centrosome regulation.
Chiba et al., Sendai, Japan. In Mol Cell, 2014
To explore further functions of BRCA1/BARD1, we performed mass spectrometry analysis and identified Obg-like ATPase 1 (OLA1) as a protein that interacts with the carboxy-terminal region of BARD1.
OLA1 in centrosome biology alongside the BRCA1/BARD1 complex: looking beyond centrosomes.
Hergovich et al., London, United Kingdom. In Mol Cell, 2014
In this issue of Molecular Cell, Chiba and colleagues (Matsuzawa et al., 2014) identify Obg-like ATPase 1 (OLA1) as an additional member of the BRCA1/BARD1/γ-tubulin complex that is critically involved in centrosome amplification and microtubule aster formation.
Interferon-beta-1b-induced short- and long-term signatures of treatment activity in multiple sclerosis.
Salamon et al., San Francisco, United States. In Pharmacogenomics J, 2013
Plausible mediators of neuronal preservation included NRF2, downregulation of OLA1, an antioxidant suppressor, and the antioxidant gene ND6, implicated in optic neuropathy and MS-like lesions.
OLA1 protects cells in heat shock by stabilizing HSP70.
Shi et al., Houston, United States. In Cell Death Dis, 2012
In this study, we investigated the role of OLA1 (Obg-like ATPase 1), a previously uncharacterized cytosolic ATPase, in regulating the turnover of HSP70.
DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies.
Huang et al., Syracuse, United States. In Mol Cancer Res, 2010
DOC45 is a novel ATPase that is linked to cellular stress response and tumorigenesis, and may also serve as a valuable tumor marker.
Knockdown of OLA1, a regulator of oxidative stress response, inhibits motility and invasion of breast cancer cells.
Shi et al., Hangzhou, China. In J Zhejiang Univ Sci B, 2009
knockdown of OLA1 inhibits breast cancer cell migration and invasion through a mechanism that involves the modulation of intracellular ROS levels
OLA1, an Obg-like ATPase, suppresses antioxidant response via nontranscriptional mechanisms.
Shi et al., Houston, United States. In Proc Natl Acad Sci U S A, 2009
OLA1 suppresses the antioxidant response through nontranscriptional mechanisms.
The identification and characterization of a new GTP-binding protein (Gbp45) involved in cell proliferation and death related to mitochondrial function.
Nishikawa et al., Ōsaka, Japan. In Cell Mol Biol Lett, 2007
Results indicate that Gbp45/OLA1 plays important roles in cell proliferation and death related to mitochondrial function.
Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins.
Kambach et al., Zürich, Switzerland. In J Biol Chem, 2007
For this reason, we have termed the protein hOLA1, for human Obg-like ATPase 1.
Proteins involved in neuronal differentiation of neuroblastoma cell line N1E-115.
Lubec et al., Vienna, Austria. In Electrophoresis, 2007
Tubulin beta 5, cat eye syndrome critical region protein 5 homolog, putative GTP-binding protein PTD004 homolog, and the metabolic proteins glyceraldehyde-3-phosphate dehydrogenase and transketolase were differentially regulated.
Derangement of hypothetical proteins in fetal Down's syndrome brain.
Lubec et al., Vienna, Austria. In Neurochem Res, 2004
By contrast, expression levels of hypothetical protein KIAA1185, hypothetical protein 55.2 kDa, hypothetical protein 58.8 kDa, actin-related protein 3beta (ARP3beta), and putative GTP-binding protein PTD004 were significantly decreased (P < 0.05) in fetal DS brain, and domain analysis suggests involvement in cytoskeleton, signaling, and chaperone system abnormalities.
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