Correlates and Consequences of Suicidal Cognitions and Behaviors in Children Ages 3 to 7 Years.
Amherst Center, United States. In J Am Acad Child Adolesc Psychiatry, Nov 2015
RESULTS: Controlling for a range of clinical and demographic variables, early-childhood SI (as defined as suicidal thoughts, behavior, or any expression of plans/attempts occurring before age 7) and suicidal themes in play were concurrently associated with childhood attention-deficit/hyperactivity (ADHD) and oppositional defiant/conduct disorders (ODD/CD).
[Development of incurable cancer cell targeted agents using viral technology].
Ōsaka, Japan. In Yakugaku Zasshi, 2012
Since tumor cells present in a hypoxic environment are known to be resistant to chemotherapy and radiotherapy, we also engineered a novel oncolytic herpes virus targeting a specific tumor microenvironment, which harbors a gene encoding a fusion protein of oxygen-dependent degradation (ODD) domain of HIF1α and ICP4, a master viral transcription factor required for replication.
Selective, reversible inhibitors of the AAA ATPase p97
Bethesda, United States. In Unknown Journal, 2011
By contrast, these probe compounds were far less potent in blocking degradation of the p97-independent substrate oxygen-dependent degradation domain (ODD)-luciferase (IC50 > 28 μM), underscoring their specificity towards p97.