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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

RANBP2-like and GRIP domain containing 2

Nucleoporin, RGP-2, C11orf5, Hrbl
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3' UTR of this gene contains an insulin receptor substrate 3-like pseudogene. [provided by RefSeq, Sep 2008] (from NCBI)
Top mentioned proteins: NUP98, Nup153, CAN, ACID, V1a
Papers using Nucleoporin antibodies
Phosphorylation of Ser-446 determines stability of MKP-7.
Blagosklonny Mikhail V., In PLoS ONE, 2004
... Antibodies against p38 MAPK, JNK2, JNK1/2, ERK1/2, Bax, Bcl2, AIF and Nucleoporin p62 were purchased from Santa Cruz Biotechnology, Inc ...
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53.
Chandra Dhyan, In PLoS ONE, 2003
... Antibodies against p38 MAPK, JNK2, JNK1/2, ERK1/2, Bax, Bcl2, AIF and Nucleoporin p62 were purchased from Santa Cruz Biotechnology, Inc ...
Papers on Nucleoporin
Nucleoporin 62 and Ca(2+) /calmodulin dependent kinase kinase 2 regulate androgen receptor activity in castrate resistant prostate cancer cells.
Edelman et al., Buffalo, United States. In Prostate, Feb 2016
CaMKK2 association with nuclear pore complexes (NPCs) and nucleoporins (Nups) including Nup62, were imaged by structured illumination and super-resolution fluorescence microscopy and co-immunoprecipitation, respectively.
NUP50 is necessary for the survival of primordial germ cells in mouse embryos.
Lee et al., Seattle, United States. In Reproduction, Jan 2016
Nucleoporin 50 kDa (NUP50), a component of the nuclear pore complex, is highly expressed in male germ cells, but its role in germ cells is largely unknown.
Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome.
Matsumoto et al., Yokohama, Japan. In Am J Hum Genet, Nov 2015
Nucleoporin 107 kDa (NUP107) is a component of the NPC central scaffold and is an essential protein in all eukaryotic cells.
Impact of Nucleoporin-Mediated Chromatin Localization and Nuclear Architecture on HIV Integration Site Selection.
Hope et al., Chicago, United States. In J Virol, Oct 2015
It has been known for a number of years that integration sites of human immunodeficiency virus type 1 (HIV-1) DNA show a preference for actively expressed chromosomal locations.
Nucleoporin 35 regulates cardiomyocyte pH homeostasis by controlling Na+-H+ exchanger-1 expression.
Chen et al., Shanghai, China. In J Mol Cell Biol, Oct 2015
The mammalian nuclear pore complex is comprised of ∼ 30 different nucleoporins (Nups).
Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane.
Kutay et al., Zürich, Switzerland. In J Cell Biol, Jul 2015
Nucleoporin depletions suggest that translocation through nuclear pore complexes (NPCs) is rate-limiting and restricted by the central NPC scaffold.
Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish.
Cui et al., Beijing, China. In Mol Cell Biol, Apr 2015
Nucleoporin p62 (Nup62) localizes in the central channel of nuclear pore complexes (NPCs) and regulates nuclear pore permeability and nucleocytoplasmic transport.
A Novel Saccharomyces cerevisiae FG Nucleoporin Mutant Collection for Use in Nuclear Pore Complex Functional Experiments.
Wente et al., Nashville, United States. In G3 (bethesda), 2014
FG nucleoporins (Nups) are the class of proteins that both generate the permeability barrier and mediate selective transport through the nuclear pore complex (NPC).
Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways.
Liu et al., T'ai-chung-shih, Taiwan. In Plos One, 2014
Here, we report for the first time that p17 functions as a nucleoporin Tpr suppressor that leads to p53 nuclear accumulation and consequently activates p53, p21, and PTEN.
The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis.
Kwon et al., Seoul, South Korea. In Int J Biol Sci, 2014
To elucidate the underlying mechanisms responsible for the antiangiogenic activity of OMe-Syn, we used phage display cloning to isolate potential OMe-Syn binding proteins from human cDNA libraries and identified nucleoporin 153 kDa (NUP153) as a primary binding partner of OMe-Syn.
Cloning, molecular characterization, and expression analysis of a nucleoporin gene (rgNUP98-96) from Rehmannia glutinosa.
Li et al., Zhengzhou, China. In Genet Mol Res, 2014
Nucleoporin 98 (NUP98) and nucleoporin 96 (NUP96) are essential components of the nuclear pore complex (NPC) in eukaryote cells.
NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights.
Aplan et al., Bethesda, United States. In Blood, 2012
Structural chromosomal rearrangements of the Nucleoporin 98 gene (NUP98), primarily balanced translocations and inversions, are associated with a wide array of hematopoietic malignancies.
Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms.
Haraguchi et al., Kōbe, Japan. In Genes Cells, 2010
The nucleoporin Nup98 is an essential component of the nuclear pore complex.
Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm.
Fornerod et al., Amsterdam, Netherlands. In Cell, 2010
Study analyzed genomic interactions of full-length nucleoporins Nup98, Nup50, and Nup62 and found that they predominantly interacted with active genes inside the nucleoplasm, particularly those involved in developmental regulation and the cell cycle.
NUP98 dysregulation in myeloid leukemogenesis.
Morrone et al., New York City, United States. In Ann N Y Acad Sci, 2007
Nucleoporin 98 (NUP98) is a component of the nuclear pore complex that facilitates mRNA export from the nucleus.
Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking.
Stewart et al., Cambridge, United Kingdom. In Cell, 2000
We describe the crystal structure of a complex between importin-beta residues 1-442 (Ib442) and five FxFG nucleoporin repeats from Nsp1p.
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