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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Nse1 Smc5-6 complex non-SMC subunit 1

Top mentioned proteins: Smc5, MUC4, Ubiquitin, RAD18, Nkx2.5
Papers on Nse1
Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA.
Palecek et al., Brno, Czech Republic. In Nucleic Acids Res, Nov 2015
Here we present evidence that the NSE1/NSE3/NSE4 sub-complex of SMC5/6 binds to double-stranded DNA without any preference for DNA-replication/recombination intermediates.
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex.
Palecek et al., Brno, Czech Republic. In Cell Cycle, 2014
NSE3, together with its partner proteins NSE1 and NSE4 form a tight subcomplex of the structural maintenance of chromosomes SMC5-6 complex.
The K+-dependent asparaginase, NSE1, is crucial for plant growth and seed production in Lotus japonicus.
Márquez et al., Sevilla, Spain. In Plant Cell Physiol, 2013
We have used reverse genetics to assess the phenotypes produced by the deficiency of K(+)-dependent NSE1 asparaginase in the model legume Lotus japonicus.
Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes.
O'Connell et al., New York City, United States. In Mol Biol Cell, 2011
Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the DNA repair
When MAGE meets RING: insights into biological functions of MAGE proteins.
Yang et al., Beijing, China. In Protein Cell, 2011
The binding mode between MAGEs and RING proteins was investigated and one important structure of these MAGE-RING complexes was solved: the MAGE-G1-NSE1 complex.
Biomarkers in prostate cancer epidemiology.
Verma et al., Rockville, United States. In Cancers (basel), 2010
Among epigenetic biomarkers, most reports indicate GSTP1 hypermethylation as the diagnostic marker for prostate cancer; however, NKX2-5, CLSTN1, SPOCK2, SLC16A12, DPYS, and NSE1 also have been reported to be regulated by methylation mechanisms in prostate cancer.
MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.
Potts et al., Dallas, United States. In Mol Cell, 2010
The crystal structure of one of these MAGE-RING complexes, MAGE-G1-NSE1, reveals structural insights into MAGE family proteins and their interaction with E3 RING ubiquitin ligases.
Architecture of the Smc5/6 Complex of Saccharomyces cerevisiae Reveals a Unique Interaction between the Nse5-6 Subcomplex and the Hinge Regions of Smc5 and Smc6.
Ye et al., Louisville, United States. In J Biol Chem, 2009
Smc5 and Smc6 associate with each other at their hinge regions and constitute the backbone of the complex, whereas the Nse1-6 subunits form three distinct subcomplexes/entities that interact with different regions of Smc5 and Smc6.
Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.
Boddy et al., Los Angeles, United States. In Mol Biol Cell, 2008
Nse1 RING-like motif is a protein-protein interaction domain required for Smc5-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions
Requirement of Nse1, a subunit of the Smc5-Smc6 complex, for Rad52-dependent postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae.
Prakash et al., Galveston, United States. In Mol Cell Biol, 2007
This study presents evidence for the requirement of Nse1, a subunit of the Smc5-Smc6 complex, in Rad52-dependent postreplication repair and a role for the Nse1 and Mms21 E3 ligase activities associated with this complex in this repair mode.
Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.
Issa et al., Houston, United States. In Plos One, 2007
Based on methylation in primary tumors compared to normal adjacent tissues, NKX2-5, CLSTN1, SPOCK2, SLC16A12, DPYS and NSE1 are candidate biomarkers for prostate cancer (methylation range 50%-85%).
A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Nakamura et al., Tokyo, Japan. In Int J Oncol, 2006
up-regulation of FAM84A may play a critical role in progression of colon cancer
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.
Boddy et al., Los Angeles, United States. In Mol Biol Cell, 2004
Nse1, Nse2, and Nse3 are crucial for meiosis. They also play an important role in mitigating the genome destabilizing effects of replication fork stalling. [Nse1]
Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Strippoli et al., Bologna, Italy. In Int J Oncol, 2004
A final list included the following genes: bone morphogenetic protein 4 (BMP4), cyclin D (CycD), family with sequence similarity 3, member D (FAM3D), gastrin (GAS), glycoprotein A33 transmembrane (GPA33), glutathione peroxidase 2 gastrointestinal (GPX2), galactoside-binding, soluble, 4 (galectin 4) (LGALS4), non-SMC, structural maintenance of chromosomes, element 1 protein (NSE1), tumor-associated calcium signal transducer 1 (TACSTD1), telomerase reverse transcriptase (hTERT), trefoil factor 3 intestinal (TFF3), transmembrane 4 superfamily member 3 (TM4SF3), UDP glycosyltransferase 1 family, polypeptide A9 (UGT1A9), villin 1 (VIL1), and the novel gene FLJ20127.
Coamplification of DDX1 correlates with an improved survival probability in children with MYCN-amplified human neuroblastoma.
Christiansen et al., Marburg an der Lahn, Germany. In J Clin Oncol, 2004
PATIENTS AND METHODS: We analyzed 98 primary neuroblastoma tumors with MYCN amplification for coamplification of seven additional genes at chromosome 2p24-25 (DDX1, NAG, NSE1, LPIN1, EST-AA581763, SMC6, and SDC1).
Chromosomal localization of DNA amplifications in neuroblastoma tumors using cDNA microarray comparative genomic hybridization.
Squire et al., Toronto, Canada. In Neoplasia, 2003
The genes HPCAL1, LPIN1/KIAA0188, NAG, and NSE1/LOC151354 were found to be coamplified with MYCN.
Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair.
Kohno et al., Ikoma, Japan. In J Biol Chem, 2002
Here, we report that NSE1 from Saccharomyces cerevisiae encodes a novel non-SMC component of the SMC5(Yol034wp)-SMC6(Rhc18p) complex corresponding to the 2-3-MDa molecular mass.
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