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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Neuronal pentraxin receptor

The protein encoded by this gene is an integral membrane protein, and functions as a neuronal receptor. It is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This site is also conserved in human and mouse. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ANP, Elongation Factor 2, CNP, NPR-B, V1a
Papers using NPR antibodies
Characterization and functional expression of the natriuretic peptide system in human lens epithelial cells.
Dimitrijevich Slobodan D. et al., In Molecular Vision, 2009
... Immunocytochemicals from Molecular Probes (Portland, OR), Calbiochem (La Jolla, CA), and Fisher Scientific (Pittsburgh, PA); NPR antibodies from Abcam (Cambridge, UK); western blot ...
Papers on NPR
An automatic method for skeletal patterns classification using craniomaxillary variables on a Colombian population.
Infante-Contreras et al., Bogotá, Colombia. In Forensic Sci Int, Jan 2016
RESULTS: An accuracy of 74.51% was obtained, defined by Pr-A-N, N-Pr-A, A-N-Pr, A-Te-Pr, A-Pr-Rhi, Rhi-A-Pr, Pr-A-Te, Te-Pr-A, Zm-A-Pr and PNS-A-Pr angles.
CORM-EDE1: A Highly Water-Soluble and Nontoxic Manganese-Based photoCORM with a Biogenic Ligand Sphere.
Westerhausen et al., Jena, Germany. In Inorg Chem, Jan 2016
The n-propylthiolate ligand (which is isoelectronic to the bridging thiolate of 1) leads to the formation of the di- and tetranuclear complexes [(OC)4Mn(μ-S-nPr)2]2 and [(OC)3Mn(μ-S-nPr)]4.
Electrophysiological effects of natriuretic peptides in the heart are mediated by multiple receptor subtypes.
Rose et al., Halifax, Canada. In Prog Biophys Mol Biol, Jan 2016
These peptides elicit their effects by binding to three distinct cell surface receptors called natriuretic peptide receptors A, B and C (NPR-A, NPR-B and NPR-C).
Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells.
Talesa et al., Perugia, Italy. In Immunol Res, Dec 2015
UNASSIGNED: Atrial natriuretic peptide (ANP) is an hormone/paracrine/autocrine factor regulating cardiovascular homeostasis by guanylyl cyclase natriuretic peptide receptor (NPR-1).
ANP-induced signaling cascade and its implications in renal pathophysiology.
Wu et al., Fribourg, Switzerland. In Am J Physiol Renal Physiol, Jun 2015
In the kidney, ANP binds to the natriuretic peptide receptor-A (NPR-A) and enhances its guanylyl cyclase activity, thereby increasing intracellular cyclic guanosine monophosphate production to promote natriuretic and renoprotective responses.
Nesfatin-1 and the Cardiovascular System: Central and Pheripheral Actions and Cardioprotection.
Cerra et al., Rende, Italy. In Curr Drug Targets, 2014
However, in the rat heart, functional studies, co-immunoprecipitation and local sequence alignment analyses suggest an interaction with the Natriuretic Peptide Receptor-type A (NPR-A).
NPR-A: A Therapeutic Target in Inflammation and Cancer.
Wang et al., Xi'an, China. In Crit Rev Eukaryot Gene Expr, 2014
Natriuretic peptide receptor A (NPR-A) is the receptor for atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP).
C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro.
Rubattu et al., Latina, Italy. In Cell Death Dis, 2014
We subsequently found that C2238/αANP induces ApoE downregulation through type C natriuretic peptide receptor (NPR-C)-dependent mechanisms involving the upregulation of miR199a-3p and miR199a-5p and the downregulation of DNAJA4.
Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function.
Chowdhury et al., Kuala Lumpur, Malaysia. In Osteoarthritis Cartilage, 2014
The chondroprotective effects were shown to be mediated by natriuretic peptide receptor (Npr)2 and enhanced synthesis of cyclic guanosine-3',5'-monophosphate (cGMP) production.
Role of the natriuretic peptide system in normal growth and growth disorders.
Jorge et al., São Paulo, Brazil. In Horm Res Paediatr, 2013
The C-type natriuretic peptide (CNP) and its receptor (NPR-B) are recognized as important regulators of longitudinal growth.
Natural polymorphisms in C. elegans HECW-1 E3 ligase affect pathogen avoidance behaviour.
Kim et al., Cambridge, United States. In Nature, 2012
Neuron-specific rescue and ablation experiments and genetic interaction analysis indicate that HECW-1 functions in a pair of sensory neurons to inhibit P. aeruginosa lawn avoidance behaviour through inhibition of the neuropeptide receptor NPR-1 (ref.
Proton-mediated chemistry and catalysis in a self-assembled supramolecular host.
Raymond et al., Berkeley, United States. In Acc Chem Res, 2009
Furthering the analogy to enzymes that obey Michaelis-Menten kinetics, we observed competitive inhibition with the inhibitor NPr(4)(+), thereby confirming that the interior cavity of the assembly was the active site for catalysis.
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases.
Suk et al., Taegu, South Korea. In Brain Res, 2009
study suggests that NCAM-120, alpha-dystroglycan, and NPR are candidate biomarkers in CSF for neurodegenerative diseases, and that the changes in the CSF level of NPR may be specific for Alzheimer's disease
Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling.
de Bono et al., Cambridge, United Kingdom. In Cell Metab, 2009
Two G protein-coupled receptors of the NPY/RFamide family, NPR-4 and NPR-5, are activated by FLP-18 peptides in vitro and exhibit mutant phenotypes that recapitulate those of flp-18 mutants.
A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans.
Kim et al., Cambridge, United States. In Science, 2009
With the use of quantitative genetic analysis, we determined that the pathogen susceptibility difference between the laboratory wild-type strain N2 and the wild isolate CB4856 is caused by a polymorphism in the npr-1 gene, which encodes a homolog of the mammalian neuropeptide Y receptor.
Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR.
Aballay et al., Durham, United States. In Science, 2008
We show that a neural circuit involving npr-1, which encodes a G protein-coupled receptor (GPCR) related to mammalian neuropeptide Y receptors, functions to suppress innate immune responses.
Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin.
Poulsen et al., Copenhagen, Denmark. In Lung Cancer, 2005
The purpose of the present study was to assess the toxic effect of taipoxin in SCLC-cell lines and to determine if toxicity correlates to NPR and NP1 and NP2 expression levels.
Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49.
Perin et al., Houston, United States. In J Biol Chem, 1997
non-AUG translation initiation site. Comparison of rat determined N-terminal amino acid sequence with cDNA sequence indicates that a CUG codon is used as an initiator codon and codes for a methionine. The CTG is present in cDNAs of mouse, rat, and human.
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