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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Nitric oxide synthase trafficker

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004] (from NCBI)
Top mentioned proteins: Nitric Oxide Synthase, beta 2-adrenoceptor, caveolin-1, Actin, HAD
Papers on NOSTRIN
Inhibition of pro-protein convertase subtilisin/kexin type 6 has a protective role against synovitis in a rat model of rheumatoid arthritis.
Pan et al., Jinan, China. In Mol Med Report, Nov 2015
Furthermore, a decrease in the mRNA levels of inflammation‑associated chemokine CXCL9, angiogenesis‑associated genes MMP‑2, MMP‑9 and NOSTRIN, hypoxia‑associated gene HIF‑1α, adhesion‑associated gene MPZL2, proliferation‑associated gene IGF‑2 and citrullination‑associated gene PADI4 was detected after PCSK6 knockdown.
The F-BAR Protein NOSTRIN Dictates the Localization of the Muscarinic M3 Receptor and Regulates Cardiovascular Function.
Oess et al., Frankfurt am Main, Germany. In Circ Res, Sep 2015
The F-BAR protein NO synthase traffic inducer (NOSTRIN) is an interaction partner of endothelial NO synthase and modulates its subcellular localization, but the role of NOSTRIN in pathophysiology in vivo is unclear.
Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in the regulation of E-cadherin in epithelial morphogenesis.
Bogdan et al., In J Cell Sci, Mar 2015
Here, we analyzed nostrin, a so-far-unknown Drosophila melanogaster F-BAR protein related to Cip4.
The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction.
Oleszczuk et al., Lublin, Poland. In J Matern Fetal Neonatal Med, 2015
OBJECTIVE: The aim of present study was to assess the maternal serum endothelial nitric oxide synthase (eNOS), NOSTRIN (eNOS-trafficking inducer) and asymmetric dimethylarginine (ADMA) levels in pregnancies with intrauterine growth restriction (IUGR) in the presence or absence of preeclampsia and to compare the results with preeclamptic pregnant women with appropriate-for-gestational-age weight infants.
Identification of the cis-element and bZIP DNA binding motifs for the autogenous negative control of mouse NOSTRIN.
Park et al., Seoul, South Korea. In Biochem Biophys Res Commun, 2014
mNOSTRIN is the mouse ortholog of hNOSTRIN.
Minocycline modulates cytokine and gene expression profiles in the brain after whole-body exposure to radiation.
Gridley et al., Loma Linda, United States. In In Vivo, 2014
Similarly, the pro-apoptotic gene Bik and nitric oxide synthase producer (Nostrin) were no longer up-regulated in the drug-treated groups.
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.
Chelala et al., London, United Kingdom. In Genome Med, 2013
Univariate assessment revealed higher expression of ITGA5, SEMA3A, KIF4A, IL20RB, SLC20A1, CDC45, PXN, SSX3 and TMEM26 was correlated with shorter survival while B3GNT1, NOSTRIN and CADPS down-regulation was associated with poor outcome.
Regulation of endothelial nitric oxide synthase activity by protein-protein interaction.
Su, Augusta, United States. In Curr Pharm Des, 2013
The negative eNOS interacting proteins include caveolin, G protein-coupled receptors (GPCR), nitric oxide synthase-interacting protein (NOSIP), and nitric oxide synthase trafficking inducer (NOSTRIN).
Knockdown of the hypertension-associated gene NOSTRIN alters glomerular barrier function in zebrafish (Danio rerio).
Schiffer et al., Hannover, Germany. In Hypertension, 2013
Using quantitative trait loci analysis, we identified the gene of the F-BAR protein NOSTRIN in the center of an overlapping region in rat and human quantitative trait loci that are associated with hypertension.
Changes in human umbilical vein endothelial cells induced by endothelial nitric oxide synthase traffic inducer.
Xiang et al., Wuhan, China. In J Huazhong Univ Sci Technolog Med Sci, 2013
This study investigated the changes in human umbilical vein endothelial cells (HUVECs) induced by overexpression of endothelial nitric oxide synthase traffic inducer (NOSTRIN) and its role in cellular injury.
[Testicular CR16 and spermatogenesis].
Xiang et al., Wuhan, China. In Zhonghua Nan Ke Xue, 2012
Research on gene regulation in spermatogenesis has become a hot spot and revealed some spermato-genesis-related genes, such as AYZ, DAZ, YRRM, NOSTRIN, and so on.
The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development.
Oess et al., Frankfurt am Main, Germany. In Embo J, 2012
NOSTRIN participates in FGF signal transduction and vascular development.
Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression.
Tzima et al., Chapel Hill, United States. In Arterioscler Thromb Vasc Biol, 2011
Results reveal an elegant mechanism of eNOS regulation by PECAM-1 through signal transducers and activators of transcription 3-mediated transcriptional control of NOSTRIN.
[Expression of NOSTRIN in the testis tissue of azoospermia patients].
Xiong et al., Wuhan, China. In Zhonghua Nan Ke Xue, 2011
The expression of NOSTRIN is decreased, while the activity of eNOS and the level of NO2-/NO3- increased in the testis tissue of azoospermia patients.
Effect of paraquat exposure on nitric oxide-responsive genes in rat mesencephalic cells.
Fuentes et al., Cáceres, Spain. In Nitric Oxide, 2010
To better understand the actions of nitric oxide and its potential role in paraquat-induced gene expression, we examined changes in GCH1, ARG1, ARG2, NOS1, NOS2, NOS3, NOSTRIN, NOSIP, NOS1AP, RASD1, DYNLL1, GUCY1A3, DDAH1, DDAH2 and CYGB genes whose expression is controlled by or involved in signaling by the second messenger nitric oxide, in rat mesencephalic cells after 3, 6, 12 and 24h of paraquat exposure.
Endothelial nitric oxide synthase traffic inducer in the umbilical vessels of the patients with pre-eclampsia.
Xu et al., Wuhan, China. In J Huazhong Univ Sci Technolog Med Sci, 2009
NOSTRIN expression was increased in umbilical vessel of women with pre-eclampsia.
NOSTRINbeta--a shortened NOSTRIN variant with a role in transcriptional regulation.
Siehoff-Icking et al., Frankfurt am Main, Germany. In Traffic, 2009
results suggest that nuclear NOSTRINbeta may negatively regulate transcription of the NOSTRIN gene
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