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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Serine/threonine kinase 38

NDR, NDR1, EDAG, nuclear Dbf2-related
Required for non-race specific resistance to bacterial and fungal pathogens.Mediates systemic acquired resistance (SAR) response. (from NCBI)
Top mentioned proteins: ACID, CAN, V1a, NDRG2, HAD
Papers on NDR
Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts.
Struhl et al., New York City, United States. In Dev Cell, Jan 2016
Nuclear Dbf2-related (NDR) kinases play a central role in limiting growth in most animals.
Nucleosomes Are Essential for Proper Regulation of a Multigated Promoter in Saccharomyces cerevisiae.
Stillman et al., United States. In Genetics, Jan 2016
We modified the HO promoter with segments from the well-studied CLN2 NDR, creating chimeric promoters differing in nucleosome occupancy but with binding sites for the same activator, SBF.
Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone-responsive element in the mouse IGF-1 gene.
Fung et al., Milwaukee, United States. In Physiol Genomics, Dec 2015
Finally, IUGR significantly altered the nucleosome-depleted region (NDR) at the in2GHRE of IGF-1 on postnatal day 21, with either complete absence of the NDR or with a shifted NDR exposing only one of two STAT5b DNA binding sites.
Rutin-Mediated Priming of Plant Resistance to Three Bacterial Pathogens Initiating the Early SA Signal Pathway.
Chu et al., China. In Plos One, Dec 2015
We also demonstrated that the rutin-mediated priming resistance was attenuated in npr1, eds1, eds5, pad4-1, ndr1 mutants, and NahG transgenic Arabidopsis plant, while not in either snc1-11, ein2-5 or jar1 mutants.
Nucleosome positioning in yeasts: methods, maps, and mechanisms.
Korber et al., München, Germany. In Chromosoma, Jun 2015
There is a conserved stereotypical nucleosome organization around transcription start sites (TSSs) with a nucleosome-depleted region (NDR) upstream of the TSS and a TSS-aligned regular array of evenly spaced nucleosomes downstream over the gene body.
Telomere mean length in patients with diabetic retinopathy.
Bansal et al., Chandīgarh, India. In Sci Rep, 2014
The study involved 120 subjects, comprising 27 non-insulin dependent diabetes mellitus (NIDDM) without any diabetic retinopathy (NDR), 45 NIDDM subjects with non-proliferative diabetic retinopathy (NPDR), 12 NIDDM subjects with proliferative diabetic retinopathy (PDR) and 36 healthy controls.
Nodal signalling determines biradial asymmetry in Hydra.
Holstein et al., Heidelberg, Germany. In Nature, 2014
We identified a Nodal-related gene (Ndr) in Hydra magnipapillata, and this gene is essential for setting up an axial asymmetry along the main body axis.
Multifaceted roles of Furry proteins in invertebrates and vertebrates.
Mizuno et al., Sendai, Japan. In J Biochem, 2014
Fry and its orthologues in invertebrates (termed Tao3p in budding yeast, Mor2p in fission yeast, Sax-2 in nematode and Fry in fruit fly) genetically and physically interact with nuclear Dbf2-related (NDR) kinases (termed Cbk1p in budding yeast, Orb6p in fission yeast, Sax-1 in nematode and Trc in fruitfly), and function as activators or scaffolds of these kinases.
AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases.
Biondi et al., Frankfurt am Main, Germany. In Biochim Biophys Acta, 2013
The group of AGC protein kinases includes more than 60 protein kinases in the human genome, classified into 14 families: PDK1, AKT/PKB, SGK, PKA, PKG, PKC, PKN/PRK, RSK, NDR, MAST, YANK, DMPK, GRK and SGK494.
Protein kinases of the Hippo pathway: regulation and substrates.
Barrufet et al., Boston, United States. In Semin Cell Dev Biol, 2012
Hippo also uses the scaffold protein Furry and a different Mob protein to control another ndr-like kinase, the morphogenetic regulator Tricornered.
Erythroid differentiation-associated gene interacts with NPM1 (nucleophosmin/B23) and increases its protein stability, resisting cell apoptosis.
Yang et al., Tianjin, China. In Febs J, 2012
EDAG enhances the protein stability of NPM1 via binding to NPM1, which plays a critical role in the anti-apoptosis of leukaemia cells.
The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1.
Hagan et al., Manchester, United Kingdom. In Nat Cell Biol, 2012
We now show that the NDR (nuclear Dbf2-related) kinase component of the fission yeast SIN, Sid2-Mob1, acts independently of the other known SIN components in G2 phase of the cell cycle to control the timing of mitotic commitment.
SR1, a calmodulin-binding transcription factor, modulates plant defense and ethylene-induced senescence by directly regulating NDR1 and EIN3.
Tang et al., Beijing, China. In Plant Physiol, 2012
SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.
Serine-threonine kinase 38 is regulated by glycogen synthase kinase-3 and modulates oxidative stress-induced cell death.
Miyagawa et al., Tokyo, Japan. In Free Radic Biol Med, 2012
GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress
Polycomb-repressed genes have permissive enhancers that initiate reprogramming.
Jones et al., Los Angeles, United States. In Cell, 2012
We observed an unexpected nucleosome-depleted region (NDR) at the H3K4me1-enriched enhancer at which transcriptional regulators initially bind, leading to subsequent changes in the chromatin at the cognate promoter.
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis.
Pasterkamp et al., Utrecht, Netherlands. In Mol Cell Biol, 2011
Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.
The role of NDR1 in pathogen perception and plant defense signaling.
Day et al., East Lansing, United States. In Plant Signal Behav, 2011
The biochemical and cellular function of NDR1 in plant immunity and defense signaling has long remained elusive.
Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.
Hemmings et al., Basel, Switzerland. In Mol Cell Biol, 2011
These findings establish a novel MST3-NDR-p21 axis as an important regulator of G(1)/S progression of mammalian cells.
A tetrapyrrole-regulated ubiquitin ligase controls algal nuclear DNA replication.
Tanaka et al., Matsudo, Japan. In Nat Cell Biol, 2011
In plant cells, organelle DNA replication (ODR) is coordinated with nuclear DNA replication (NDR), with ODR preceding NDR during cell cycle progression.
The nuts and bolts of AGC protein kinases.
Alessi et al., Dundee, United Kingdom. In Nat Rev Mol Cell Biol, 2010
The family comprises some intensely examined protein kinases (such as Akt, S6K, RSK, MSK, PDK1 and GRK) as well as many less well-studied enzymes (such as SGK, NDR, LATS, CRIK, SGK494, PRKX, PRKY and MAST).
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