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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Nanos homolog 3

nanos1, Nanos homolog
Top mentioned proteins: PGC, miR, Pumilio, CAN, MEN
Papers on nanos1
A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis.
Miller et al., Toronto, Canada. In J Neurosci, Dec 2015
UNLABELLED: Here, we have asked about post-transcriptional mechanisms regulating murine developmental neurogenesis, focusing upon the RNA-binding proteins Smaug2 and Nanos1.
Genetics of primary ovarian insufficiency: new developments and opportunities.
Chen et al., Jinan, China. In Hum Reprod Update, Nov 2015
Based on candidate gene studies, single gene perturbations unequivocally having a deleterious effect in at least one population include Bone morphogenetic protein 15 (BMP15), Progesterone receptor membrane component 1 (PGRMC1), and Fragile X mental retardation 1 (FMR1) premutation on the X chromosome; Growth differentiation factor 9 (GDF9), Folliculogenesis specific bHLH transcription factor (FIGLA), Newborn ovary homeobox gene (NOBOX), Nuclear receptor subfamily 5, group A, member 1 (NR5A1) and Nanos homolog 3 (NANOS3) seem likely as well, but mostly being found in no more than 1-2% of a single population studied.
Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.
Lee et al., In J Biol Chem, 2014
NANOS1); these levels were rescued by ectopic expression of KDM2A but not its catalytic mutant.
Tetracycline derivative minocycline inhibits autophagy and inflammation in concanavalin-a-activated human hepatoma cells.
Annabi et al., Montréal, Canada. In Gene Regul Syst Bio, 2013
Minocycline was also shown to inhibit ConA-induced signal transducer and activator of transcription 3 (STAT3) phosphorylation as well as gene expression of NANOS1, a biomarker believed to colocalize with MT1-MMP and the specific silencing of which further inhibited ConA-induced STAT3 phosphorylation.
Mutations of NANOS1, a human homologue of the Drosophila morphogen, are associated with a lack of germ cells in testes or severe oligo-astheno-teratozoospermia.
Jaruzelska et al., Poznań, Poland. In J Med Genet, 2013
BACKGROUND: The Nanos gene is a key translational regulator of specific mRNAs involved in Drosophila germ cell development.
Molecular and expression characterization of a nanos1 homologue in Chinese sturgeon, Acipenser sinensis.
Cao et al., Wuhan, China. In Gene, 2013
The nanos gene family was essential for germ line development in diverse organisms.
A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency.
Xu et al., Nanjing, China. In Cell Death Dis, 2012
Although the Nanos gene family is known to be required for PGC development and maintenance in diverse model organisms, the relevance of this information to human biology is not yet clear.
Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese population.
Wang et al., Nanjing, China. In Plos One, 2012
BACKGROUND: The meiotic program initiation pathway genes (CYP26B1, NANOS1 and STRA8) have been proposed to play key roles in spermatogenesis.
Localisation of RNAs into the germ plasm of vitellogenic Xenopus oocytes.
Woodland et al., Coventry, United Kingdom. In Plos One, 2012
Concentrating on RNA encoding the Xenopus Nanos homologue, nanos1 (formerly Xcat2), we find that it consistently localised into aggregated germ plasm ribonucleoprotein (RNP) particles, independently of cytoskeletal integrity.
C1q-like factor, a target of miR-430, regulates primordial germ cell development in early embryos of Carassius auratus.
Gui et al., Wuhan, China. In Int J Biol Sci, 2012
Knockdown of CaOC1q resulted in a significant reduction of primordial germ cells (PGCs) in Carassius auratus, as shown by whole mount in situ hybridization with vasa-specific RNA probe, fluorescence immunostaining of vasa protein, and GFP imaging of the GFP-nanos1-3'UTR mRNA reporter.
ΦC31 integrase mediates efficient cassette exchange in the zebrafish germline.
Fisher et al., Philadelphia, United States. In Dev Dyn, 2011
Utilizing codon-optimized ΦC31 integrase RNA bearing the 3'UTR from the nanos1 gene, we replaced the egfp coding sequence of an integrated reporter transgene with mCherry coding sequence.
NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.
Jaruzelska et al., Poznań, Poland. In Histochem Cell Biol, 2011
NANOS1-PUMILIO2 complex, together with GEMIN3 and small noncoding RNAs, possibly regulate mRNA translation within the chromatoid body of the human germ cells.
Xenopus germline nanos1 is translationally repressed by a novel structure-based mechanism.
King et al., Miami, United States. In Development, 2011
The translational repressor Nanos is expressed in the germline and stem cell populations of jellyfish as well as humans.
Zebrafish Nanos interacts with and regulates the phosphorylation of Mylz2.
Deng et al., Wuhan, China. In Biochimie, 2010
Data show a novel interaction between zebrafish Nanos and myosin light chain II (Mylz2).
The mechanism for primordial germ-cell migration is conserved between Japanese eel and zebrafish.
Yamaha et al., Nanae, Japan. In Plos One, 2010
dead-end, nanos1, and cxcr4) are highly conserved across phylum boundaries.
Crystal structure of zinc-finger domain of Nanos and its functional implications.
Sato et al., Yokohama, Japan. In Embo Rep, 2010
These results provide the structural basis for further studies to clarify Nanos function.
Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma.
Pieler et al., Göttingen, Germany. In Proc Natl Acad Sci U S A, 2010
The part of XDE-LE critical for somatic RNA clearance exhibits homology to zebrafish nanos1 and appears to be targeted by Xenopus miR-18 for somatic mRNA clearance.
Purification, crystallization and initial X-ray diffraction study of the zinc-finger domain of zebrafish Nanos.
Sato et al., Yokohama, Japan. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009
Preliminary x ray diffraction studies the C-terminal domain (residues 59-159) of zebrafish Nanos, is reported.
The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor subunit composition.
Zinn et al., Pasadena, United States. In J Neurosci, 2009
Regulatory interplay between Nos and Pumilio (Pum) could cause a small change in Pum activity to be amplified into a large shift in the balance between GluRIIA and GluRIIB subunit synapses.
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