A widespread glutamine-sensing mechanism in the plant kingdom.
Tübingen, Germany. In Cell, 2014
The plastid-localized PII signaling protein controls, in a glutamine-dependent manner, the key enzyme of the ornithine synthesis pathway, N-acetyl-l-glutamate kinase (NAGK), that leads to arginine and polyamine formation.
The network of P(II) signalling protein interactions in unicellular cyanobacteria.
Tübingen, Germany. In Adv Exp Med Biol, 2009
At least one of these functions, regulation of arginine biosynthesis by controlling the key enzyme N-acetyl-L: -glutamate kinase (NAGK), was transmitted by the ancestral cyanobacterium, which gave rise to chloroplasts, into the eukaryotic domain and was conserved during the evolution of planta.
PII in higher plants: a modern role for an ancient protein.
Calgary, Canada. In Trends Plant Sci, 2009
Previous findings suggest that PII-N-acetylglutamate kinase (NAGK) complex formation controls l-arginine biosynthesis, whereas other work implicates PII in regulating chloroplastic NO2(-) uptake.
Arginine and nitrogen storage.
Valencia, Spain. In Curr Opin Struct Biol, 2008
When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK).