The role of TRIB1 in lipid metabolism; from genetics to pathways.
Tochigi, Japan. In Biochem Soc Trans, Nov 2015
Furthermore, novel binding partner, Sin3A (Swi-independent 3A)-associated protein, 18 kDa, was identified, which activates microsomal TG transfer protein (MTTP) expression by binding with MTTP regulatory elements in co-ordination with mSin3A and TRIB1.
TET proteins and epigenetic modifications in cancers.
Łódź, Poland. In Postepy Hig Med Dosw (online), 2014
EZH2, OGT, Sin3a or HCF1) and by affecting their activity and, chromatin binding ability, they can cause changes in patterns of histone methylation, acetylation and O-GlcNAcylation.
A molecular mechanism for circadian clock negative feedback.
Boston, United States. In Science, 2011
analysis indicates PSF within the PER complex recruits SIN3A, a scaffold for assembly of transcriptional inhibitory complexes, and the PER complex thereby rhythmically delivers histone deacetylases to the Per1 promoter, which repress Per1 transcription