The molecular regulation of muscle stem cell function.
Ottawa, Canada. In Cold Spring Harb Symp Quant Biol, 2007
Extensive genetic analysis has revealed that Myf5 and MyoD are required for myogenic determination, whereas myogenin and MRF4 have roles in terminal differentiation.
Mox2 is a component of the genetic hierarchy controlling limb muscle development.
London, United Kingdom. In Nature, 1999
Among the genes known to be important for muscle development in mammalian embryos are those encoding the basic helix-loop-helix (bHLH) myogenic regulatory factors (MRFs; MyoD, Myf5, myogenin and MRF4) and Pax3, a paired-type homeobox gene that is critical for the development of limb musculature.