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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Myelin protein zero

This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. [provided by RefSeq, Apr 2010] (from NCBI)
Top mentioned proteins: CAN, V1a, HAD, PrP, ACID
Papers using MPP antibodies
Mouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes.
Laudet Vincent, In PLoS ONE, 2006
... ICI 182780 and the ERα specific antagonist 4,4′,4″-(4-Propyl-[1H] pyrazole-1,3,5-triyl) trisphenol (MPP), were purchased from Tocris (Ellisville, MO) ...
Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources
Schmidt Ulrike, In PLoS ONE, 1976
... separate experiments, cells were pre-treated with i) 10 mM NAC for 2 h; ii) 100 nM MPP ERα antagonist (Tocris Cookson, Ellisville, MO) for ...
Papers on MPP
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.
Nijnik et al., Montréal, Canada. In Cell Death Differ, Feb 2016
Specifically, Mysm1(-/-)Puma(-/-) mice show full rescue of multipotent progenitor (MPP) viability, partial rescue of HSC quiescence and function, but persistent lymphopenia.
Myelin in Cartilaginous Fish.
de Bellard, Canada. In Brain Res, Feb 2016
More importantly, the ultrastructure of their compact myelin is indistinguishable from the one observed in tetrapods and the first true myelin basic protein (MBP) and myelin protein zero (MPZ) seem to have originated on cartilaginous fish or their ancestors, the placoderms.
Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson's disease.
Hu et al., Nanjing, China. In Neuroscience, Feb 2016
Similarly, AQP4 deficiency augmented the activation of NF-κB pathway and the production of IL-1β and TNF-α in midbrain astrocyte cultures treated with MPP(+) (1-methyl-4-phenylpyridinium).
Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease.
Fournier et al., Mont-Saint-Aignan, France. In Biochim Biophys Acta, Feb 2016
Hence, we explored the putative autophagy-modulating properties of PACAP in in vitro and in vivo models of PD, using the neurotoxic agents 1-methyl-4-phenylpyridinium (MPP(+)) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), respectively, to trigger alterations of DA neurons.
The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.
Wu et al., Shanghai, China. In Biochem Biophys Res Commun, Feb 2016
PD cell models were established by using methyl-4-phenylpyridinium(MPP(+)), which induced inhibition of cell proliferation, cell cycle arrest and apoptosis.
[Phenotypes of Charcot-Marie-Tooth Syndrome and Differential Diagnosis Focused in Inflammatory Neuropathies].
Iijima, Nagoya, Japan. In Brain Nerve, Jan 2016
CMT1 is the autosomal-dominant demyelinating form, and CMT1A (mostly PMP22 duplication) is the most frequent subtype, followed by CMTX1, HNPP (hereditary neuropathy with liability to pressure palsies), CMT1B, or CMT2.
Clinical impacts of a micropapillary pattern in lung adenocarcinoma: a review.
Yuan et al., Hangzhou, China. In Onco Targets Ther, Dec 2015
Micropapillary-predominant adenocarcinoma (MPA), which is defined by micropapillary pattern (MPP), is the primary histological pattern observed semiquantitatively in 5% increments on resection specimens, and MPA was formally determined to be a new histological subtype according to the new multidisciplinary classification in 2011.
Involvement of membrane skeletal molecules in the Schmidt-Lanterman incisure in Schwann cells.
Ohno et al., Matsumoto, Japan. In Med Mol Morphol, Dec 2015
4.1R-MPP (membrane palmitoylated protein) 1-glycophorin C is one of the basic molecular complexes of the membrane skeleton.
Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.
Goukassian et al., Boston, United States. In Front Oncol, 2014
We report here that low-dose (1)H- and (56)Fe-IR significantly decreased the hematopoietic early and late multipotent progenitor (E- and L-MPP, respectively) cell numbers in mouse BM over a period of up to 10 months after exposure.
Green Tea Catechin, EGCG, Suppresses PCB 102-Induced Proliferation in Estrogen-Sensitive Breast Cancer Cells.
Bauer et al., Indianapolis, United States. In Int J Breast Cancer, 2014
Furthermore, the proliferative effects of PCB 102 were mediated by ERα and could be abrogated by the selective ERα antagonist MPP.
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Trumpp et al., Heidelberg, Germany. In Cell Stem Cell, 2014
In this study, we present integrated quantitative proteome, transcriptome, and methylome analyses of hematopoietic stem cells (HSCs) and four multipotent progenitor (MPP) populations.
Developmental regulation of insulin receptor gene in sciatic nerves and role of insulin on glycoprotein P0 in the Schwann cells.
Muttagi et al., India. In Peptides, 2012
steady-state levels of insulin receptor mRNA increase during development and after postnatal day 10, when the peak of myelin structural gene (P0) expression occurs, increasing further in parallel with the growth of the myelin sheath
MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot-Marie-Tooth disease type 1B.
Shy et al., Detroit, United States. In Brain, 2012
results provide a potential link between the accumulation of MpzR98C in the endoplasmic reticulum and a developmental delay in myelination.
A novel MPZ gene mutation in exon 2 causing late-onset demyelinating Charcot-Marie-Tooth disease.
Hadjivassiliou et al., Sheffield, United Kingdom. In J Clin Neuromuscul Dis, 2012
Thiss study demonistrated that two affected member of the same family with the same genotype had an 8-base pair deletion, c.160_167delTCCCGGGT in MPZ exon 2.
Phenotypic presentation of the Ser63Del MPZ mutation.
Shy et al., Detroit, United States. In J Peripher Nerv Syst, 2012
Patients with CMT1B caused by Ser63del MPZ have a classical CMT1 phenotype that is much less severe than that of patients with Arg98Cys MPZ
Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy.
Anderson et al., Chapel Hill, United States. In J Immunol, 2012
Mutant autoimmune regulator protein-mediated central tolerance to Mpz initiates an autoimmune T helper type (Th)1 cell effector response toward peripheral nerves.
INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy.
Mollet et al., Paris, France. In N Engl J Med, 2012
METHODS: We performed direct genotyping of INF2 in 16 index patients with Charcot-Marie-Tooth neuropathy and FSGS who did not have a mutation in PMP22 or MPZ, encoding peripheral myelin protein 22 and myelin protein zero, respectively.
Straight talk with...Ellen 't Hoen.
Mullard, In Nat Med, 2010
The initiative-called the Medicines Patent Pool (MPP)-aims to streamline licensing processes, drive the combination of multiple HIV medicines into one pill and foster the development of drug formulations for children.
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death.
Park et al., Ottawa, Canada. In Nat Cell Biol, 2010
Overexpression of Ape1(WT) and Ape1(T232A), but not the phosphorylation mimic Ape1(T232E), protects neurons against MPP(+)/MPTP.
IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses.
Artis et al., Philadelphia, United States. In Nature, 2010
Here we show that IL25, a member of the IL17 cytokine family, promotes the accumulation of a lineage-negative (Lin(-)) multipotent progenitor (MPP) cell population in the gut-associated lymphoid tissue that promotes T(H)2 cytokine responses.
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