Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
Beijing, China. In Hum Mol Genet, Mar 2015
We also replicated 14 previously reported loci, 8 (CASZ1, MOV10, FGF5, CYP17A1, SOX6, ATP2B1, ALDH2, and JAG1) at genome-wide significance, and 6 (FIGN, ULK4, GUCY1A3, HFE, TBX3-TBX5, and TBX3) at a suggestive level of P = 1.81 × 10(-3) to 5.16 × 10(-8).
Host restriction factors in retroviral infection: promises in virus-host interaction.
East Lansing, United States. In Retrovirology, 2011
Here, we review recent progress on the rapidly growing field of restriction factors, focusing on the antiretroviral activities of APOBEC3G, TRIM5, tetherin, SAMHD1, MOV10, and cellular microRNAs (miRNAs), and the counter-activities of Vif, Vpu, Vpr, Vpx, and Nef.
A diverse range of gene products are effectors of the type I interferon antiviral response.
New York City, United States. In Nature, 2011
Broadly acting effectors included IRF1, C6orf150 (also known as MB21D1), HPSE, RIG-I (also known as DDX58), MDA5 (also known as IFIH1) and IFITM3, whereas more targeted antiviral specificity was observed with DDX60, IFI44L, IFI6, IFITM2, MAP3K14, MOV10, NAMPT (also known as PBEF1), OASL, RTP4, TREX1 and UNC84B (also known as SUN2).
MOV10 as a novel telomerase-associated protein.
Tokyo, Japan. In Biochem Biophys Res Commun, 2009
These data suggest that MOV10 is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.
Prolyl 4-hydroxylation regulates Argonaute 2 stability.
Boston, United States. In Nature, 2008
Proteins such as Dicer, TRBP, MOV10, RHA, RCK/p54 and KIAA1093 associate with Ago proteins and participate in small RNA processing, RISC loading and localization of Ago proteins in the cytoplasmic messenger RNA processing bodies.
MicroRNA silencing through RISC recruitment of eIF6.
Philadelphia, United States. In Nature, 2007
Here we show that human RISC (RNA-induced silencing complex) associates with a multiprotein complex containing MOV10--which is the homologue of Drosophila translational repressor Armitage--and proteins of the 60S ribosome subunit.