Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology.
Canada. In Eur J Paediatr Neurol, Jan 2016
Median levels of MMP-1, MMP-2, TIMP-1, TIMP-2, sE-selectin, sICAM-1, sVCAM-1, IL-8, IL-10, TNF-alpha, VEGF, Fetuin A were found to be higher in the neonatal group when compared with older children.
Drug Design targeting the CXCR4/CXCR7/CXCL12 pathway.
Omaha, United States. In Curr Top Med Chem, Oct 2015
However, the crosstalk between CXCL12/CXCR7/CXCR4 and other signaling pathways (such as the p38 MAPK pathway, the PI3K/mTOR pathway, the STAT3 signaling, and metalloproteinases MMP-9 and MMP-2) is more complicated.
[Endothelial microparticles (EMP) in physiology and pathology].
In Postepy Hig Med Dosw (online), 2014
Apart from their procoagulant properties, it was demonstrated that EMP may express adhesive molecules and metalloproteinases (MMP-2, MMP-9) at their surface and release growth factors, which may contribute to angiogenesis.