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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Melanoma inhibitory activity

may be involved in cartilage development [RGD, Feb 2006] (from NCBI)
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Top mentioned proteins: CAN, ACID, HAD, V1a, PrP
Papers using MIA antibodies
PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells
Mazzoccoli Gianluigi et al., In PPAR Research, 2011
... serum (FCS), 100 U/mL penicillin, and 100 ng/mL streptomycin (Invitrogen Life Technologies, Milan, Italy) while CFPAC-1 and MIA PaCa-2 were maintained in RPMI medium (Invitrogen Life Technologies, Milan, Italy) ...
Papers on MIA
Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease.
Kroemer et al., Villejuif, France. In Trends Biochem Sci, Feb 2016
UNASSIGNED: Members of the coiled-coil-helix-coiled-coil-helix (CHCH) domain-containing protein family that carry (CX9C) type motifs are imported into the mitochondrion with the help of the disulfide relay-dependent MIA import pathway.
Circulating melanoma exosomes as diagnostic and prognosis biomarkers.
González et al., Spain. In Clin Chim Acta, Jan 2016
The aim of this study was to identify and evaluate the presence of the melanoma biomarkers MIA, S100B and tyrosinase-related protein 2 (TYRP2) in exosomes and their potential clinical utility.
Animal models of prenatal immune activation in depression research.
Pollak et al., Vienna, Austria. In Curr Neuropharmacol, Jan 2016
Supported by human and animal studies, maternal immune activation (MIA) has been intimately associated with the development of schizophrenia.
Transient receptor potential ankyrin 1 (TRPA1) receptor is involved in chronic arthritis: in vivo study using TRPA1-deficient mice.
Helyes et al., Pécs, Hungary. In Arthritis Res Ther, Dec 2015
METHODS: Chronic arthritis was induced by complete Freund's adjuvant (CFA), knee osteoarthritis by monosodium iodoacetate (MIA) in TRPA1 knockout (KO) mice and C57Bl/6 wildtype mice.
Maternal immune activation produces neonatal excitability defects in offspring hippocampal neurons from pregnant rats treated with poly I:C.
Attali et al., Tel Aviv-Yafo, Israel. In Sci Rep, Dec 2015
Maternal immune activation (MIA) resulting from prenatal exposure to infectious pathogens or inflammatory stimuli is increasingly recognized to play an important etiological role in neuropsychiatric disorders with neurodevelopmental features.
Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol.
Chacinska et al., Warsaw, Poland. In Nature, Sep 2015
Complex machineries which maintain the specificity of protein import and sorting include the TIM23 translocase responsible for the transfer of precursor proteins into the matrix, and the mitochondrial intermembrane space import and assembly (MIA) machinery required for the biogenesis of intermembrane space proteins.
The MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis.
Tokatlidis et al., Glasgow, United Kingdom. In Acc Chem Res, Sep 2015
Among them, the import pathway that targets proteins to the intermembrane space (IMS) stands out as it is the only one that couples import to folding and oxidation and results in the covalent modification of the incoming precursor that adopt internal disulfide bonds in the process (the MIA pathway).
The poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery.
Pollak et al., Vienna, Austria. In Pharmacol Ther, May 2015
Corresponding preclinical model systems based upon maternal immune activation (MIA) by treatment of the pregnant female have been developed.
Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression.
Jiao et al., Roma, Italy. In Lancet, Mar 2015
We validated our findings in PDAC cell-lines (PANC-1, MIA PaCa-2, LPc006, and LPc167), subcutaneous PDAC xenografts in mice, and laser capture microdissected PDACs from patients (n=91).
Changes in Astroglial Markers in a Maternal Immune Activation Model of Schizophrenia in Wistar Rats are Dependent on Sex.
Gonçalves et al., Porto Alegre, Brazil. In Front Cell Neurosci, 2014
The maternal immune activation (MIA) animal model is used to study how an insult directed at the maternal host can have adverse effects on the fetus, leading to behavioral and neurochemical changes later in life.
Multiple intestinal atresia with combined immune deficiency.
Notarangelo, Boston, United States. In Curr Opin Pediatr, 2014
PURPOSE OF REVIEW: To update on the molecular and cellular basis of multiple intestinal atresia (MIA).
Serum pregnancy-associated plasma protein A correlates with inflammation and malnutrition in patients treated with maintenance hemodialysis.
Kuśnierz-Cabala et al., Kraków, Poland. In Folia Med Cracov, 2014
Advanced chronic kidney disease (CKD) leads to complications such as anemia, electrolyte abnormalities, bone and mineral disorder, and malnutrition-inflammation-atherosclerosis (MIA) syndrome, that result in high cardiovascu- lar mortality.
Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells.
Esumi et al., Kiev, Ukraine. In World J Gastroenterol, 2014
Moreover, the expression and hypoxia responsibility of PFKFB-4 and PFKFB-3 was also shown for pancreatic (Panc1, PSN-1, and MIA PaCa-2) as well as gastric (MKN45 and NUGC3) cancer cells.
Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders.
Mazmanian et al., Pasadena, United States. In Cell, 2014
We demonstrate GI barrier defects and microbiota alterations in the maternal immune activation (MIA) mouse model that is known to display features of ASD.
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Pandolfi et al., Boston, United States. In Nat Genet, 2013
We show that ZBTB7A physically interacts with SOX9 and functionally antagonizes its transcriptional activity on key target genes such as MIA, which is involved in tumor cell invasion, and H19, a long noncoding RNA precursor for an RB-targeting microRNA.
Evaluation of multiple serum markers in advanced melanoma.
González et al., Pamplona, Spain. In Tumour Biol, 2011
Results show that S-100B, MIA and LDH levels were significantly higher in patients with advanced melanoma than in disease-free patients or healthy controls.
Impact of lymph node metastases on serum level of melanoma inhibitory activity in stage III melanoma patients.
Trefzer et al., Berlin, Germany. In J Dermatol, 2011
assessed the utility of melanoma inhibitory activity (MIA) serum marker in the follow up and primary diagnosis of stage III melanoma patients
Receiver operating characteristic analysis: calculation for the marker 'melanoma inhibitory activity' in metastatic uveal melanoma patients.
Schaller et al., München, Germany. In Melanoma Res, 2011
Further diagnostics should be initiated in uveal melanoma patients with serum MIA above 8.3ng/ml.
Plasma markers for identifying patients with metastatic melanoma.
Halaban et al., New Haven, United States. In Clin Cancer Res, 2011
Data suggest that plasma markers: CEACAM, ICAM-1, osteopontin, MIA, TIMP-1 and S100B particularly when assessed in combination, can be used to monitor patients for disease recurrenc.
Enhanced cartilage regeneration in MIA/CD-RAP deficient mice.
Bosserhoff et al., Regensburg, Germany. In Cell Death Dis, 2009
Expression analysis of cartilage tissue derived from MIA-/- mice revealed strong downregulation of nuclear RNA-binding protein 54-kDa.
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