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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Pitrilysin metallopeptidase 1

Top mentioned proteins: CAN, V1a, HAD, thrombospondin-1, MMP-9
Papers using metalloprotease antibodies
Aggrecan protects cartilage collagen from proteolytic cleavage
Prehm Peter et al., In Arthritis Research & Therapy, 2002
... Polyclonal antibodies to matrix metalloprotease (MMP)9 were from Biomol (Hamburg, Germany) ...
Papers on metalloprotease
Associations of Promoter Methylations and mRNA Expressions of MMP-2, MMP-7 and MMP-9 with Primary Fallopian Tube Carcinoma.
Zhang et al., Huzhou, China. In Gynecol Obstet Invest, Feb 2016
OBJECTIVE: To explore the associations of matrix metalloprotease-2 (MMP-2), MMP-7 and MMP-9 methylations and messenger ribonucleic acid (mRNA) expressions with primary fallopian tube carcinoma (PFTC) development and prognosis.
Rituximab-refractory thrombotic thrombocytopenic purpura responsive to intravenous but not subcutaneous bortezomib.
Wang et al., Buffalo, United States. In Transfusion, Feb 2016
BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is often characterized by formation of antibodies against a disintegrin and metalloprotease with thrombospondin repeat, member 13 (ADAMTS13).
The Protease Ste24 Clears Clogged Translocons.
Schuldiner et al., Israel. In Cell, Feb 2016
To shed light on the machinery required to resolve clogging, we carried out a systematic screen in Saccharomyces cerevisiae that highlighted a role for the ER metalloprotease Ste24.
Cellular prion protein regulates invasion and migration of breast cancer cells through MMP-9 activity.
Lee et al., Seoul, South Korea. In Biochem Biophys Res Commun, Feb 2016
Overexpressed PrP(C) increases matrix metalloprotease-9 (MMP-9) expression by enhancing association of NF-κB in promoter of MMP-9 gene and ERK signaling in MCF-7 cells.
Plasma ADAMTS-13 protein is not associated with portal hypertension or hemodynamic changes in patients with cirrhosis.
Møller et al., Hvidovre, Denmark. In Dig Liver Dis, Jan 2016
BACKGROUND: Activated hepatic stellate cells synthesize the matrix metalloprotease ADAMTS13, which may be involved in the development of liver cirrhosis and portal hypertension.
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain.
Lichtenthaler et al., Kiel, Germany. In Prog Neurobiol, Dec 2015
Proteins belonging to the 'A Disintegrin And Metalloproteinase' (ADAM) family are membrane-anchored proteases that are able to cleave the extracellular domains of several membrane-bound proteins in a process known as 'ectodomain shedding'.
Role of fluid shear stress in regulating VWF structure, function and related blood disorders.
Neelamegham et al., Buffalo, United States. In Biorheology, Dec 2015
Once in blood, the protein multimer distribution is dynamically regulated by fluid shear stress which has two opposing effects: it promotes the aggregation or self-association of multiple VWF units, and it simultaneously reduces multimer size by facilitating the force-dependent cleavage of the protein by various proteases, most notably ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type repeats, motif 1 type 13).
Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis.
Kaufmann et al., Berlin, Germany. In Semin Immunopathol, Nov 2015
Gradients of cytokines and chemokines (CCR2, CXCR2, CXCR3/CXCR5 agonists; TNF/IL-10, IL-1/IFN-I), expression of activation/death markers on immune cells (TNF receptor 1, PD-1, IL-27 receptor) or abundance of enzymes [arginase-1, matrix metalloprotease (MMP)-1, MMP-8, MMP-9] drive genesis and progression of lesions.
The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.
Léopold et al., Nice, France. In Nature, Jul 2015
Grnd also promotes the invasiveness of Ras(V12)/scrib(-/-) tumours through Egr-dependent Matrix metalloprotease-1 (Mmp1) expression.
The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair.
Dellaire et al., Halifax, Canada. In Biomolecules, 2014
Of interest is the COP9 signalosome (CSN), a multi-subunit metalloprotease present in eukaryotes that removes NEDD8 from cullins and regulates the activity of cullin-RING ubiquitin ligases (CRLs).
First trimester serum tests for Down's syndrome screening.
Alfirevic et al., Liverpool, United Kingdom. In Cochrane Database Syst Rev, 2014
We evaluated 78 test combinations formed from combinations of 18 different tests, with or without maternal age; ADAM12 (a disintegrin and metalloprotease), AFP (alpha-fetoprotein), inhibin, PAPP-A (pregnancy-associated plasma protein A, ITA (invasive trophoblast antigen), free βhCG (beta human chorionic gonadotrophin), PlGF (placental growth factor), SP1 (Schwangerschafts protein 1), total hCG, progesterone, uE3 (unconjugated oestriol), GHBP (growth hormone binding protein), PGH (placental growth hormone), hyperglycosylated hCG, ProMBP (proform of eosinophil major basic protein), hPL (human placental lactogen), (free αhCG, and free ßhCG to AFP ratio.
Isolation and identification of a novel fibrinolytic Bacillus tequilensis CWD-67 from dumping soils enriched with poultry wastes.
So et al., In J Gen Appl Microbiol, 2014
The enzyme was completely inhibited by PMSF and significantly inhibited by EDTA, TPCK, Co(2+), Zn(2+), and Cu(2+), suggesting a chymotrypsin-like serine metalloprotease.
Botulinum neurotoxins: genetic, structural and mechanistic insights.
Montecucco et al., Padova, Italy. In Nat Rev Microbiol, 2014
Neurotoxigenic clostridia belong to six phylogenetically distinct groups and produce more than 40 different BoNT types, which inactivate neurotransmitter release owing to their metalloprotease activity.
C. elegans Punctin specifies cholinergic versus GABAergic identity of postsynaptic domains.
Bessereau et al., France. In Nature, 2014
These proteins belong to the ADAMTS (a disintegrin and metalloprotease with thrombospondin repeats)-like family, a class of extracellular matrix proteins related to the ADAM proteases but devoid of proteolytic activity.
A DNA-dependent protease involved in DNA-protein crosslink repair.
Jentsch et al., Martinsried, Germany. In Cell, 2014
Here, we identify the metalloprotease Wss1 as being crucial for cell survival upon exposure to formaldehyde and topoisomerase 1-dependent DNA damage.
Targeting capacity and conservation of PreP homologues localization in mitochondria of different species.
Glaser et al., Stockholm, Sweden. In J Mol Biol, 2011
Data show that the hPreP presequence only targets GFP to the matrix of mammalian and yeast mitochondria.
Decreased proteolytic activity of the mitochondrial amyloid-β degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria.
Yan et al., New York City, United States. In J Alzheimers Dis, 2010
This study demonstrated decreased proteolytic activity of the mitochondrial amyloid-beta degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria.
Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP.
Graff et al., Stockholm, Sweden. In Neurosci Lett, 2010
our data suggest that genetic variation in the hPreP gene PITRM1 may potentially contribute to mitochondrial dysfunctions
Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
Yamada et al., Japan. In Int J Mol Med, 2009
Data revealed that six polymorphisms of F10, PITRM1, PCSK2, JPH3, MYO7B, and AKAP12 were related (P<0.05) to the prevalence of chronic kidney disease.
ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.
Liu et al., New York City, United States. In Mol Cell Biol, 2009
Findings demonstrate that ADAMTS-7, a direct target of PTHrP signaling, negatively regulates endochondral bone formation by associating with and inactivating GEP chondrogenic growth factor.
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