Papers using
MEK5
antibodies
Papers on
MEK5
Susceptible genes of restless legs syndrome in migraine.Wang et al., Taipei, Taiwan. In Cephalalgia, Jan 2016
METHODS: Thirteen single-nucleotide polymorphisms (SNPs) at six RLS risk loci (MEIS1, BTBD9, MAP2K5, PTPRD, TOX3, and an intergenic region on chromosome 2p14) were genotyped in 211 migraine patients with RLS and 781 migraine patients without RLS.
Association of low ferritin with PLM in the Wisconsin Sleep Cohort.Mignot et al., Palo Alto, United States. In Sleep Med, Nov 2015
Analyses were performed using a linear model with PLM category above and below 15 PLM/h (periodic leg movement index, PLMI) as the dependent variable, and adjusting for known covariates, including previously associated single-nucleotide polymorphisms (SNPs) within BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD.
Gαq signalling: the new and the old.Ribas et al., Madrid, Spain. In Cell Signal, 2014
Recently, the activation of ERK5 MAPK by Gq-coupled receptors has also been described as a novel PLCβ-independent signalling axis that relies upon the interaction between this G protein and two novel effectors (PKCζ and MEK5).
What model organisms and interactomics can reveal about the genetics of human obesity.Schiöth et al., Uppsala, Sweden. In Cell Mol Life Sci, 2012
Here, we searched biological databases and discovered 33 additional genes associated with human obesity (CADM2, GIPR, GPCR5B, LRP1B, NEGR1, NRXN3, SH2B1, FANCL, GNPDA2, HMGCR, MAP2K5, NUDT3, PRKD1, QPCTL, TNNI3K, MTCH2, DNAJC27, SLC39A8, MTIF3, RPL27A, SEC16B, ETV5, HMGA1, TFAP2B, TUB, ZNF608, FAIM2, KCTD15, LINGO2, POC5, PTBP2, TMEM18, TMEM160).
Meta-analysis identifies common variants associated with body mass index in east Asians.Shu et al., Nashville, United States. In Nat Genet, 2012
We identified ten BMI-associated loci at genome-wide significance (P < 5.0 × 10(-8)), including seven previously identified loci (FTO, SEC16B, MC4R, GIPR-QPCTL, ADCY3-DNAJC27, BDNF and MAP2K5) and three novel loci in or near the CDKAL1, PCSK1 and GP2 genes.
ERK5 and its role in tumour development.Cook et al., Cambridge, United Kingdom. In Biochem Soc Trans, 2012
The MEK5 [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase 5]/ERK5 pathway is the least well studied MAPK signalling module.
MEK5/ERK5 pathway: the first fifteen years.Beckman et al., New Orleans, United States. In Biochim Biophys Acta, 2012
While conventional MAP kinase pathways are one of the most highly studied signal transduction molecules, less is known about the MEK5 signaling pathway.
Genome-wide association studies of sleep disorders.Wu et al., Philadelphia, United States. In Chest, 2011
These studies have identified four gene variants associated with restless legs syndrome (BTBD9, MEIS1, MAP2K5/LBXCOR1, and PTPRD) and two variants associated with narcolepsy (one in the T-cell receptor α locus and another between CPT1B and CHKB).
MAP kinase signalling cascade in Arabidopsis innate immunity.Sheen et al., Boston, United States. In Nature, 2002
Here we identify a complete plant MAP kinase cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) and WRKY22/WRKY29 transcription factors that function downstream of the flagellin receptor FLS2, a leucine-rich-repeat (LRR) receptor kinase.