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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Membrane bound O-acyltransferase domain containing 1

MBOAT1 shares structural similarity with a superfamily of membrane-bound O-acetyltransferases that transfer organic compounds, usually fatty acids (e.g., cholesterol, diacylglycerol, palmitoyl), onto hydroxyl groups of membrane-embedded targets (Dauwerse et al., 2007 [PubMed 17440500]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: ACID, ZAP-70, Lipoprotein Lipase, RIP140, HAD
Papers on MBOAT1
Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment.
Neri et al., Cosenza, Italy. In Leuk Res, Aug 2015
Two (SNORA70F, NRIP1) of the down-regulated and 6 (SEPT10, ZNF667, TGFBR3, MBOAT1, LPL, CRY1) of the up-regulated genes were significantly associated with a reduced risk of disease progression in both sets.
Microdeletions on 6p22.3 are associated with mesomelic dysplasia Savarirayan type.
Spielmann et al., Berlin, Germany. In J Med Genet, Jul 2015
The deletions encompass four known genes: MBOAT1, E2F3, CDKAL1 and SOX4.
Gene expression profiling identifies ARSD as a new marker of disease progression and the sphingolipid metabolism as a potential novel metabolism in chronic lymphocytic leukemia.
Morra et al., Milano, Italy. In Cancer Biomark, 2010
RESULTS: We found LPL, AGPAT2, MBOAT1, CHPT1, AGPAT4, PLD1 genes encoding enzymes involved in lipid metabolism overexpressed in UMZAP70(+).
Drosophila lysophospholipid acyltransferases are specifically required for germ cell development.
Treisman et al., New York City, United States. In Mol Biol Cell, 2009
Our findings suggest that lysophospholipid acyltransferase activity is essential for germline development and could provide a mechanistic explanation for the etiology of the human MBOAT1 mutation.
Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils.
Voelker et al., Aurora, United States. In J Biol Chem, 2008
The major yeast lysophospholipid acyltransferase, Ale1p, is related to mammalian membrane-bound O-acyltransferase (MBOAT) proteins.
A family of eukaryotic lysophospholipid acyltransferases with broad specificity.
Ronne et al., Uppsala, Sweden. In Febs Lett, 2008
The budding yeast ALE1 gene encodes a lysophospholipid acyltransferase (LPLAT) with broad specificity.
Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors.
Höglund et al., Lund, Sweden. In Bmc Med Genomics, 2007
By combining genomic profiles with expression profiles we could show that amplification of E2F3, CDKAL1, SOX4, and MBOAT1 as well as NUP153, AOF1, FAM8A1 and DEK in 6p22 was associated with increased gene expression.
A t(4;6)(q12;p23) translocation disrupts a membrane-associated O-acetyl transferase gene (MBOAT1) in a patient with a novel brachydactyly-syndactyly syndrome.
Peters et al., Leiden, Netherlands. In Eur J Hum Genet, 2007
One of the genes on chromosome 6, the membrane-associated O-acetyl transferase gene 1 (MBOAT1), was disrupted by the breakpoint.
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