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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Glutathione transferase zeta 1

MAI, MA1, maleylacetoacetate isomerase, MAAI, GSTZ1
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, ACID, AGE, MM2
Papers using MAI antibodies
Discovery of a 1,5 dihydrobenzo (b)(1) diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly.
Kaufmann Gunnar F., In PLoS ONE, 2010
... Antibodies were obtained from commercial sources: anti-GST (Sigma–Aldrich), anti-core (MA1-080) (Thermo Scientific), anti-NS3 [H23] (Ab138830-Abcam), anti-LAMP1 ...
The hallmarks of cancer
Thévenod Frank et al., In Molecular Cancer, 1999
... # MA1-250; 1:1000) from Dianova GmbH (Hamburg, Germany), anti-TCF4 ...
Papers on MAI
Formation Dynamics of CH3NH3PbI3 Perovskite Following Two-Step Layer Deposition.
Johnston et al., Oxford, United Kingdom. In J Phys Chem Lett, Feb 2016
Here we follow the real-time formation dynamics of MAPbI3 from a bilayer of lead iodide (PbI2) and methylammonium iodide (MAI) deposited through a two-step thermal evaporation process.
Malformin A1 promotes cell death through induction of apoptosis, necrosis and autophagy in prostate cancer cells.
Yuan et al., Jinan, China. In Cancer Chemother Pharmacol, Jan 2016
PURPOSE: Malformin A1 (MA1), a cyclopentapeptide isolated from fungal origin, has been identified to induce varieties of intriguing biological activities.
2-Amino-2-deoxy-glucose conjugated cobalt ferrite magnetic nanoparticle (2DG-MNP) as a targeting agent for breast cancer cells.
Güray et al., Ankara, Turkey. In Environ Toxicol Pharmacol, Jan 2016
In addition, the gene expression levels of four drug-metabolizing enzymes, two Phase I (CYP1A1, CYP1B1) and two Phase II (GSTM3, GSTZ1) were also increased with the high concentrations of 2DG-MNPs.
Determination of Myo-Inositol in Infant, Pediatric, and Adult Formulas by Liquid Chromatography-Pulsed Amperometric Detection with Column Switching: Collaborative Study, Final Action 2011.18.
Schimpf et al., Columbus, United States. In J Aoac Int, Dec 2015
With this method free myo-inositol and phosphatidylinositol bound myo-inositol are extracted using two different sample preparation procedures, separated by ion chromatography using a combination of Dionex Carbo Pac PA1 and MA1 columns with column switching, and detected with pulsed amperometry using a gold electrode.
Generation and Characterization of Monoclonal Antibodies Specific to Avian Influenza H5N1 Hemagglutinin Protein.
Gupta et al., New Delhi, India. In Monoclon Antib Immunodiagn Immunother, Dec 2015
One of the MAbs (MA-1) also showed hemagglutination inhibition activity (HI titer; 31.25 μg/mL) against the homologous A/turkey/Turkey/1/2005 H5N1 virus.
From invagination to navigation: The story of magnetosome-associated proteins in magnetotactic bacteria.
Zarivach et al., Beersheba, Israel. In Protein Sci, Nov 2015
It is known that magnetosome formation is tightly controlled by a distinctive set of magnetosome-associated proteins that are encoded mainly in a genomically conserved region within MTB called the magnetosome island (MAI).
Successful endovascular treatment of three fusiform cerebral aneurysms with the Pipeline Embolization Device in a patient with dilating HIV vasculopathy.
Tubman et al., Minneapolis, United States. In J Neurointerv Surg, 2014
Vessel wall invasion by varicella zoster virus, HIV or Mycobacterium avium intracellulare complex (MAI) has been postulated as a possible etiology.
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans.
Willerslev et al., Copenhagen, Denmark. In Nature, 2014
Here we sequence the draft genome of an approximately 24,000-year-old individual (MA-1), from Mal'ta in south-central Siberia, to an average depth of 1×.
Susceptibility to exudative age-related macular degeneration and three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1).
Saadat et al., Shīrāz, Iran. In Eur J Ophthalmol, 2012
Our study did not support any association between susceptibility to exudative AMD (age-related macular degeneration) and polymorphisms of GSTZ1.
Susceptibility to breast cancer and three polymorphisms of GSTZ1.
Saadat et al., Shīrāz, Iran. In Dna Cell Biol, 2012
polymorphisms of GSTZ1 showed strong linkage disequilibrium among cancer patients and control su
Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate.
Stacpoole et al., Gainesville, United States. In Drug Metab Dispos, 2012
Data suggest neonatal onset and age-related increase in GSTZ1 protein expression during liver development/growth. GSTZ1 haplotype influences activity with dichloroacetate but not protein expression.
Genetic polymorphisms of glutathione S-transferase Z1 in an Iranian population.
Saadat et al., Shīrāz, Iran. In Mol Biol Rep, 2011
Results describe the genotypic frequencies of glutathione S-transferase Z1 polymorphisms among an Iranian population.
Association between three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to schizophrenia.
Saadat et al., In Psychiatry Res, 2011
The results of this study did not support the association between genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to schizophrenia.
Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice.
Anders et al., Canberra, Australia. In Drug Metab Rev, 2011
GSTZ1-1 was also found to be identical with maleylacetoacetate isomerase, which catalyzes the penultimate step in the tyrosine-degradation pathway.
In patients younger than age 55 years with lymph node-negative breast cancer, proliferation by mitotic activity index is prognostically superior to adjuvant!
Baak et al., Stavanger, Norway. In J Clin Oncol, 2011
We compared the accuracy of the online program Adjuvant!, the Norwegian Breast Cancer Group (NBCG) guidelines, and the proliferation factor mitotic activity index (MAI) in patients with lymph node (LN) -negative disease (pN0).
Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers.
Zur Hausen et al., Stavanger, Norway. In Breast Cancer Res Treat, 2009
Independent studies have shown that in node negative breast cancer patients less than 71 years, the proliferation marker mitotic activity index (MAI) is the strongest, most well reproducible prognosticator and chemotherapy success predictor.
Role of dichloroacetate in the treatment of genetic mitochondrial diseases.
Langaee et al., Gainesville, United States. In Adv Drug Deliv Rev, 2008
DCA is metabolized by and inhibits the bifunctional zeta-1 family isoform of glutathione transferase/maleylacetoacetate isomerase.
Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years.
Janssen et al., Amsterdam, Netherlands. In J Clin Oncol, 2005
PURPOSE: To validate the independent strong prognostic value of mitotic activity index (MAI) in lymph node (LN) -negative invasive breast cancer patients younger than 55 years in a nationwide multicenter prospective study.
Glutathione transferases.
Jowsey et al., Dundee, United Kingdom. In Annu Rev Pharmacol Toxicol, 2004
Furthermore, knockout of mouse GSTA4 and GSTZ1 leads to overexpression of transferases in the Alpha, Mu, and Pi classes, an observation suggesting they are part of an adaptive mechanism that responds to endogenous chemical cues such as 4-hydroxynonenal and tyrosine degradation products.
Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography.
Molthoff et al., Amsterdam, Netherlands. In J Clin Oncol, 2002
Mitotic activity index (MAI), amount of necrosis, number of lymphocytes, and tumor cells/volume were assessed.
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