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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

AlkB, alkylation repair homolog 2

Top mentioned proteins: GLB2, V1a, CAN, demethylase, ABH4
Papers on mABH2
DNA repair is indispensable for survival after acute inflammation.
Samson et al., Cambridge, United States. In J Clin Invest, 2012
ALKBH2 and ALKBH3 provide cancer protection similar to that of the DNA glycosylase AAG and display apparent epistasis with Aag
Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts.
O'Connor et al., Duarte, United States. In Dna Repair (amst), 2012
Although both Alkbh2 and Alkbh3 can protect against methyl methanesulfonate-induced cell death, only Alkbh2 shows statistically significant protection against mutations following treatment with this exogenous methylating agent.
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.
Klungland et al., Oslo, Norway. In Cancer Res, 2008
Furthermore, cation exchange chromatography of nuclear extracts from wild-type and mABH2(-/-) mice indicates that mABH2 is the principal dioxygenase for epsilon A repair in vivo.
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
Klungland et al., Oslo, Norway. In Embo J, 2006
We demonstrate that mice lacking functional mABH2 or mABH3 genes, or both, are viable and without overt phenotypes.
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues.
O'Connor et al., Duarte, United States. In J Biol Chem, 2005
In this report, we demonstrate that the mouse homologues of the alpha-ketoglutarate Fe(II) oxygen-dependent enzymes mAbh2 and Abh3 have activities comparable to those of their human counterparts.
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