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Olfactory receptor 151

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, MOR23, GPCR, iMpact
Papers on M71
In Vitro Mutational Analysis of the β2 Adrenergic Receptor, an In Vivo Surrogate Odorant Receptor.
Feinstein et al., New York City, United States. In Plos One, 2014
By contrast, when both the Nt and Ct of mβ2AR are replaced with those of M71 OR, plasma membrane trafficking is impaired.
In Vitro Mutational and Bioinformatics Analysis of the M71 Odorant Receptor and Its Superfamily.
Feinstein et al., New York City, United States. In Plos One, 2014
We performed an extensive mutational analysis of the canonical mouse odorant receptor (OR) M71 to determine the properties of ORs that inhibit plasma membrane trafficking in heterologous expression systems.
Desertibacter xinjiangensis sp. nov., isolated from the soil of a Euphrates poplar forest, and emended description of the genus Desertibacter.
Peng et al., Wuhan, China. In Int J Syst Evol Microbiol, 2014
A pale pink and strictly aerobic bacterium, designated strain M71(T), was isolated from the soil of a Euphrates poplar forest in Xingjiang, PR China.
Using the olfactory system as an in vivo model to study traumatic brain injury and repair.
Belluscio et al., Bethesda, United States. In J Neurotrauma, 2014
Interestingly, by using the M71-IRES-tauLacZ reporter line to track OSN organization, we further determined that inducing neural activity during the recovery period with intense odor conditioning did not enhance the recovery process.
Postnatal odorant exposure induces peripheral olfactory plasticity at the cellular level.
Grosmaitre et al., Gif-sur-Yvette, France. In J Neurosci, 2014
Here we exposed MOR23-green fluorescent protein (GFP) and M71-GFP mice to lyral or acetophenone, ligands for MOR23 or M71, respectively.
The β2-adrenergic receptor as a surrogate odorant receptor in mouse olfactory sensory neurons.
Mombaerts et al., Frankfurt am Main, Germany. In Mol Cell Neurosci, 2014
Here, we characterize a novel gene-targeted mouse strain in which the mouse β2-adrenergic receptor (β2AR) is coexpressed with tauGFP in OSNs that choose the OR locus M71 for expression (β2AR→M71-GFP).
[Interrelation between structural state, physicochemical properties and lipid composition in microbial cells].
Goloshchapov et al., In Biofizika, 2013
Structural state, the lipid composition and physicochemical properties of lipids of the three gram-negative bacteria (Renobacter vacuolatum, Flectobacillus major WKM 869, Pseudomonas fluorescens) during their growth and mycelium of four species of the xylotrophic basidiomycetes (Panus tigrinus IBK-131, Fomes fomentarius M71, Laetiporus sulfureus M131, Piptoporus betulinus M60) during the lag phase were also studied.
Homotypic and heterotypic adhesion induced by odorant receptors and the β2-adrenergic receptor.
Trembleau et al., Paris, France. In Plos One, 2012
We report here the first evidence for homo- and heterotypic adhesion between cells overexpressing the ORs MOR256-17 or M71, supporting the hypothesis that ORs may contribute to olfactory axon sorting by mediating differential adhesion between axons.
Insights on the susceptibility of plant pathogenic fungi to phenazine-1-carboxylic acid and its chemical derivatives.
Evidente et al., Portici, Italy. In Nat Prod Res, 2012
aureofaciens strain M71 produced two phenazine compounds as main secondary metabolites.
Postnatal experience modulates functional properties of mouse olfactory sensory neurons.
Ma et al., Philadelphia, United States. In Eur J Neurosci, 2012
We next analyzed the response properties, including rise time, decay time, and adaptation, induced by repeated stimulation in MOR23 and M71 neurons.
Structural characterization of the O-chain polysaccharide from an environmentally beneficial bacterium Pseudomonas chlororaphis subsp. aureofaciens strain M71.
Corsaro et al., Napoli, Italy. In Carbohydr Res, 2012
aureofaciens strain M71 was isolated from the root of a tomato plant and it was able to control in vivo Fusarium oxysporum f. sp.
A common gene exclusion mechanism used by two chemosensory systems.
Rodriguez et al., Genève, Switzerland. In Eur J Neurosci, 2009
We show, in vivo, that the genetic replacement of the V1rb2 pheromone receptor coding sequence by an unrelated one from the odorant receptor gene M71 maintains gene exclusion, suggesting that a common mechanism is used to regulate their transcription.
Specificity of olfactory receptor interactions with other G protein-coupled receptors.
Hall et al., Atlanta, United States. In J Biol Chem, 2007
co-expression with three subtypes of purinergic receptor (P2Y(1)R, P2Y(2)R, and A(2A)R) resulted in markedly enhanced plasma membrane localization of M71
A contextual model for axonal sorting into glomeruli in the mouse olfactory system.
Mombaerts et al., New York City, United States. In Cell, 2004
Replacements between the coding regions of the M71 and M72 OR genes reroute axons to their respective glomeruli.
Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons.
Mombaerts et al., New York City, United States. In Nature, 2004
Using permanent genetic marking, we show that the choice by an OSN to express an allele of the OR gene M71 is irreversible.
Odorant receptors instruct functional circuitry in the mouse olfactory bulb.
Katz et al., Durham, United States. In Nature, 2002
To investigate whether odorant receptors organize neural circuitry in the olfactory bulb, we have examined a genetically modified mouse line, rI7 --> M71, in which a functionally characterized receptor, rI7, has been substituted into the M71 receptor locus.
Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system.
Mombaerts et al., New York City, United States. In Cell, 1999
The projection pattern is disrupted by deleting the coding region of VR2, but an unrelated seven-transmembrane protein, the odorant receptor M71, can partially substitute for VR2.
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