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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Leucine rich repeat containing 8 family, member D

Top mentioned proteins: LRRC8, SOCS3, oncostatin M, cis-2, MKP-3
Papers on LRRC8D
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.
Jentsch et al., Berlin, Germany. In Embo J, Jan 2016
We show that the loss of subunits LRRC8A and LRRC8D of the heteromeric LRRC8 volume-regulated anion channels (VRACs) increased resistance to clinically relevant cisplatin/carboplatin concentrations.
VRAC: molecular identification as LRRC8 heteromers with differential functions.
Voss et al., Berlin, Germany. In Pflugers Arch, Jan 2016
Furthermore, first major insights on the role of LRRC8 proteins in cancer drug resistance and apoptosis and the role of LRRC8D in cisplatin and taurine transport will be summarized.
The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.
Ploegh et al., Cambridge, United States. In J Biol Chem, 2014
We show that LRRC8D is a mammalian protein required for the import of the antibiotic blasticidin S. We characterize localization and topology of LRRC8A and LRRC8D and demonstrate that LRRC8D interacts with LRRC8A, LRRC8B, and LRRC8C.
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
Yaspo et al., Berlin, Germany. In J Biol Chem, 2011
LRRC8D is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
Comparison between the stochastic search variable selection and the least absolute shrinkage and selection operator for genome-wide association studies of rheumatoid arthritis.
Chen et al., Los Angeles, United States. In Bmc Proc, 2008
SSVS and LASSO identify seven common loci, and some of them are on genes LRRC8D, LRP1B, and COLEC12.
Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal.
Steffen et al., Warsaw, Poland. In Bmc Genomics, 2008
Among those, PIM1, BCL2, IL-8, HBEGF, DUSP6, OSM, CISH, SOCS2, SOCS3, LIF and IL13 were down-regulated and RPS24, SQSTM1, TMEM1, LRRC8D, ECOP, YY1AP1, C1orf63, ASAH1, SLC25A46 and MIA3 were up-regulated.
LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.
Hara et al., Suita, Japan. In Febs Lett, 2004
identified four genes, named TA-LRRP, AD158, LRRC5, and FLJ23420, as unknown LRRC8-like genes
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