Recognition of lipopolysaccharide pattern by TLR4 complexes.
South Korea. In Exp Mol Med, 2012
The common structural pattern of LPS in diverse bacterial species is recognized by a cascade of LPS receptors and accessory proteins, LPS binding protein (LBP), CD14 and the Toll-like receptor4 (TLR4)-MD-2 complex.
Invertebrate immune diversity.
Washington, D.C., United States. In Dev Comp Immunol, 2011
These include a Toll/TLR system, a primitive complement system, an LPS binding protein, and a RAG core/Transib element.
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage.
Vienna, Austria. In Nature, 2002
Lipopolysaccharide (LPS), an outer-membrane component of Gram-negative bacteria, interacts with LPS-binding protein and CD14, which present LPS to toll-like receptor 4 (refs 1, 2), which activates inflammatory gene expression through nuclear factor kappa B (NF kappa B) and mitogen-activated protein-kinase signalling.