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Kruppel-like factor 7

KLF7, Kruppel-like factor 7
Top mentioned proteins: CAN, ACID, SET, SP1, p21
Papers on KLF7
Polymorphisms in the promoter region of the bovine lactoferrin gene influence milk somatic cell score and milk production traits in Chinese Holstein cows.
Yang et al., Yangzhou, China. In Res Vet Sci, Dec 2015
The software MatInspector revealed that these SNPs were located within several potential transcription factor binding sites, including NF-κB p50, KLF7 and SP1, and may alter gene expression, but further investigation will be required to elucidate the biological and practical relevance of these SNPs.
Kruppel-like factor family genes are expressed during Xenopus embryogenesis and involved in germ layer formation and body axis patterning.
Cao et al., Nanjing, China. In Dev Dyn, Oct 2015
In the present study, we further investigated comprehensively the expression and functions of the klf family genes, klf2, klf5, klf6, klf7, klf8, klf11, klf15, and klf17, during the embryogenesis of Xenopus laevis.
Autistic and Rett-like features associated with 2q33.3-q34 interstitial deletion.
Kim et al., Seoul, South Korea. In Am J Med Genet A, Sep 2015
Candidate genes were identified as NRP2, ADAM23, KLF7, CREB1, MAP2, UNC80, and LANCL1 for the 2q33.3-q34
Genomic Study of Cardiovascular Continuum Comorbidity.
Puzyrev et al., Tomsk, Russia. In Acta Naturae, Jul 2015
A total of 14 genetic variants were associated with a combination of several diseases of cardiovascular continuum (CVC), including those in the TAS2R38, SEZ6L, APOA2, KLF7, CETP, ITGA4, RAD54B, LDLR, and MTAP genes, along with intragenic variants rs1333048, rs1333049, and rs6501455.
Investigation of susceptibility genes triggering lachrymal/salivary gland lesion complications in Japanese patients with type 1 autoimmune pancreatitis.
Kawa et al., Matsumoto, Japan. In Plos One, 2014
Among them, KLF7, FRMD4B, LOC101928923, and MPPED2 were further examined for complication susceptibility using additional SNPs that were not included in the GWAS.
Borrelidin Isolated from Streptomyces sp. Inhibited Adipocyte Differentiation in 3T3-L1 Cells via Several Factors Including GATA-Binding Protein 3.
Imamura et al., In Biol Pharm Bull, 2014
Borrelidin increased mRNA expression of negative regulators of differentiation such as GATA-binding protein (GATA) 3, Krüppel-like factor (KLF) 3 and KLF7, as well as positive regulators, KLF4, KLF6 and KLF15, at early stages of differentiation.
Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system.
Vogel et al., Nijmegen, Netherlands. In Bmc Genomics, 2014
Analysis of evolutionarily conserved transcription factor binding sites in the promoters of these genes revealed almost all known OXPHOS regulators (including GABP, NRF1/2, SP1, YY1, E-box factors) and a set of novel candidates (ELK1, KLF7, SP4, EHF, ZNF143, and TEL2).
Different methylation profiles between intestinal and diffuse sporadic gastric carcinogenesis.
Cho et al., Wŏnju, South Korea. In Clin Res Hepatol Gastroenterol, 2014
DNAs, isolated from each group were analyzed to determine the methylation status of 6 genes (GDNF, RORA, MINT25, KLF7, CDH1, LINE-1) using pyrosequencing.
MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity.
Guo et al., Nanjing, China. In Mol Cell Endocrinol, 2014
MiR-146b in human visceral adipocytes inhibited the expression of KLF7, a member of the Kruppel-like transcription factors, as demonstrated by a firefly luciferase reporter assay, indicating that KLF7 is a direct target of the endogenous miR-146b.
[The preliminary study of gene copy number variation association with scar hyperplasia based on the whole-gene resequencing].
Yan et al., Beijing, China. In Zhonghua Wai Ke Za Zhi, 2014
They were growth factor receptor-bound 7 (Grb7), mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), mitogen-activated protein kinase kinase kinase 15 (MAP3K15), kruppel-like factors 7 (KLF7) and NK2 homeobox 2 (NKX2-2).
Luna, a Drosophila KLF6/KLF7, is maternally required for synchronized nuclear and centrosome cycles in the preblastoderm embryo.
Mlodzik et al., New York City, United States. In Plos One, 2013
Krüppel like factors (KLFs) are conserved transcription factors that have been implicated in many developmental processes including differentiation, organ patterning, or regulation of stem cell pluripotency.
A dominant mutation in FBXO38 causes distal spinal muscular atrophy with calf predominance.
Houlden et al., Baltimore, United States. In Am J Hum Genet, 2013
FBXO38 is a known coactivator of the transcription factor Krüppel-like factor 7 (KLF7), which regulates genes required for neuronal axon outgrowth and repair.
Comparative Transcriptome Analysis of Adipose Tissues Reveals that ECM-Receptor Interaction Is Involved in the Depot-Specific Adipogenesis in Cattle.
Lee et al., Suwŏn, South Korea. In Plos One, 2012
EGR2, FAS, and KLF7) were up-regulated and those in the immune system process were down-regulated.
Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract.
Bixby et al., Milwaukee, United States. In Proc Natl Acad Sci U S A, 2012
Data show that adult corticospinal tract (CST) neurons failed to up-regulate KLF7 in response to axon injury, and overexpression of VP16-KLF7 in vivo promoted both sprouting and regenerative axon growth in the CST of adult mice.
Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development.
di Porzio et al., Napoli, Italy. In Exp Cell Res, 2011
lack of a KLF family member affects dopaminergic neuron development.
Transcription factor KLF7 regulates differentiation of neuroectodermal and mesodermal cell lineages.
di Porzio et al., Napoli, Italy. In Exp Cell Res, 2010
KLF7 inactivation in Klf7-null mice decreases the expression of the neurogenic marker brain lipid-binding protein/fatty acid-binding protein 7 (BLBP/FABP7) in neural stem cells (NSCs).
Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Hansen et al., Copenhagen, Denmark. In Eur J Endocrinol, 2009
We identified a novel association between the minor A-allele of KLF7 and protection against obesity in the Danish population
(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells.
Lee et al., South Korea. In Am J Physiol Endocrinol Metab, 2007
Upregulation of adiponectin protein by (-)-catechin may involve, at least in part, suppression of KLF7 in 3T3-L1 cells.
Signal transduction induced by opioids in immune cells: a review.
Gabrilovac et al., Zagreb, Croatia. In Neuroimmunomodulation, 2005
Micro-opioids inhibited synthesis of common transcription factors AP-1, c-fos, NF-kappaB, and nuclear factor of activated T cells in activated or stimulated immune cells, whereas micro-opioids activated NF-kappaB, GATA-3, and Kruppel-like factor 7 transcription factors in non-stimulated immune cells.
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