gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

TAO kinase 3

Top mentioned proteins: ACID, HAD, CAN, STEP, fibrillin-1
Papers on Kds
Probing the Interaction between cHAVc3 Peptide and the EC1 Domain of E-cadherin using NMR and Molecular Dynamics Simulations.
Siahaan et al., Jakarta, Indonesia. In J Biomol Struct Dyn, Feb 2016
The dissociation constants (Kd values) of cHAVc3 peptide to EC1 were estimated using the NMR chemical shifts data and the estimated Kds are in the range of 0.5 × 10(-5) to 7.0 × 10(-5) M.
RAS/effector interactions from structural and biophysical perspective.
Shifman et al., Jerusalem, Israel. In Mini Rev Med Chem, Nov 2015
Most RAS/effector complexes are short-lived, demonstrating fast association and fast dissociation rate and Kds ranging from 10-8 - 10-5 M, compatible with the signaling function of these interactions in the cell.
Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B).
Tate et al., Cambridge, United Kingdom. In Biochim Biophys Acta, Oct 2015
In contrast, the mutants G44V and G346V bound tetracycline 4-5 fold more weakly than TetA(B), with Kds of 28 μM and 36 μM, respectively, whereas the mutant R70G bound tetracycline 3-fold more strongly (Kd 2.1 μM).
Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA.
Cech et al., Boulder, United States. In Mol Cell, Mar 2015
RepA RNA is a good binding partner for PRC2, while multiple non-relevant RNAs, including bacterial mRNAs, also bind PRC2; Kds depend to some extent on the experimental conditions.
Red wine proteins: two dimensional (2-D) electrophoresis and mass spectrometry analysis.
Simonato et al., Verona, Italy. In Food Chem, 2015
The potassium-DS (KDS) protein complexes obtained were treated with different solutions in order to remove the detergent.
High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication.
Prasad et al., New York City, United States. In Mol Ther Nucleic Acids, 2014
Second-generation RNA aptamers selected from partially randomized pools based on two of the aptamer sequences displayed striking enhancements in binding (Kds = 2-22 nmol/l) and inhibition (Kis = 31-49 nmol/l).
Cell-SELEX-based selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells.
Fang et al., Shenyang, China. In Biomaterials, 2014
This process generated seven aptamers that displayed highly specific binding to the target cells with Kds in the nanomolar range.
Comparative biochemical analysis of the major yolk protein in the sea urchin egg and coelomic fluid.
Robinson et al., St. John's, Canada. In Dev Growth Differ, 2014
Circular dichroic spectral analysis and endogenous tryptophan measurements of the purified 170- and 180 kDa species revealed distinctive secondary and tertiary structural features with notable differences in their responses to calcium: apparent Kds of 245- and 475 μmol/L were measured for the 170- and 180 kDa species, respectively.
Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.
Alam et al., Durham, United States. In J Virol, 2014
HIV-1 Env gp140 proteins bound to Galcer liposomes with Kds (dissociation constants) in the nanomolar range.
Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically.
Ferré-D'Amaré et al., Bethesda, United States. In Chem Biol, 2014
Crystallographic studies now show that, despite having micromolar Kds, four different fragments bind the TPP riboswitch site-specifically, occupying the pocket that recognizes the aminopyrimidine of TPP.
Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter.
Amzel et al., New Haven, United States. In Nat Commun, 2013
Here to uncover mechanistic information on NIS, we use statistical thermodynamics to obtain Kds and estimate the relative populations of the different NIS species during Na(+)/anion binding and transport.
Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
Campopiano et al., Edinburgh, United Kingdom. In Biochem Soc Trans, 2012
SPT is a PLP (pyridoxal 5'-phosphate)-dependent enzyme that forms 3-KDS (3-ketodihydrosphingosine) through a decarboxylative Claisen-like condensation reaction.
Role of fatty acid binding proteins and long chain fatty acids in modulating nuclear receptors and gene transcription.
Kier et al., College Station, United States. In Lipids, 2008
Recent advances provide insights into how poorly water-soluble lipid nutrients [LCFA; retinoic acid (RA)] and their metabolites (long chain fatty acyl Coenzyme A, LCFA-CoA) reach nuclei, bind their cognate ligand-activated receptors, and regulate transcription for signaling lipid and glucose catabolism or storage: (i) while serum and cytoplasmic LCFA levels are in the 200 mircroM-mM range, real-time imaging recently revealed that LCFA and LCFA-CoA are also located within nuclei (nM range); (ii) sensitive fluorescence binding assays show that LCFA-activated nuclear receptors [peroxisome proliferator-activated receptor-alpha (PPARalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha)] exhibit high affinity (low nM KdS) for LCFA (PPARalpha) and/or LCFA-CoA (PPARalpha, HNF4alpha)-in the same range as nuclear levels of these ligands; (iii) live and fixed cell immunolabeling and imaging revealed that some cytoplasmic lipid binding proteins [liver fatty acid binding protein (L-FABP), acyl CoA binding protein (ACBP), cellular retinoic acid binding protein-2 (CRABP-2)] enter nuclei, bind nuclear receptors (PPARalpha, HNF4alpha, CRABP-2), and activate transcription of genes in fatty acid and glucose metabolism; and (iv) studies with gene ablated mice provided physiological relevance of LCFA and LCFA-CoA binding proteins in nuclear signaling.
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).
Putman et al., Irvine, United States. In Cns Drug Rev, 2005
In the present article, we review the pharmacological properties of KDS-4103 (URB597), a highly potent and selective inhibitor of the enzyme fatty-acid amide hydrolase (FAAH), which catalyzes the intracellular hydrolysis of the endocannabinoid anandamide.
Nitric oxide interaction with insect nitrophorins and thoughts on the electron configuration of the {FeNO}6 complex.
Walker, Tucson, United States. In J Inorg Biochem, 2005
In both insects the NO is bound to the ferric form of the protein, which gives rise to Kds in the micromolar to nanomolar range, and thus upon injection of the saliva into the tissues of the victim the NO can dissociate to cause vasodilation and inhibition of platelet aggregation.
share on facebooktweetadd +1mail to friends