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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Jumonji domain containing 1C

JMJD1C, TRIP8, jumonji domain containing 1C, DKFZp761F0118
Top mentioned proteins: Histone, demethylase, Jumonji, ACID, HAD
Papers on JMJD1C
Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.
Lagergren et al., Uppsala, Sweden. In Int J Cancer, Apr 2016
SNPs within JMJD1C were associated with risk of EAC in females (p = 0.001).
Histone Modifier Genes Alter Conotruncal Heart Phenotypes in 22q11.2 Deletion Syndrome.
Morrow et al., United States. In Am J Hum Genet, Jan 2016
Three genes including JMJD1C (jumonji domain containing 1C), RREB1 (Ras responsive element binding protein 1), and SEC24C (SEC24 family member C) had rare (MAF < 0.001) predicted deleterious single-nucleotide variations (rdSNVs) in seven case subjects and no control subjects (p = 0.005; Fisher exact and permutation tests).
Replication and hematological characterization of human platelet reactivity genetic associations in men from the Caerphilly Prospective Study (CaPS).
Johnson et al., Framingham, United States. In J Thromb Thrombolysis, Nov 2015
Previously, our group performed a genome-wide association study of platelet reactivity identifying single nucleotide polymorphisms (SNPs) associated with ADP- and epinephrine- induced aggregation, including SNPs in MRVI1, PIK3CG, JMJD1C, and PEAR1, among others.
A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.
Friedlander et al., Singapore, Singapore. In Genes Nutr, Nov 2015
We further replicated the associations between common index variants at the NTAN1/PDXDC1 locus and n-6 PUFAs LA and DGLA, and between the JMJD1C locus and n-6 PUFA LA (p value between 0.0490 and 9.88 × 10(-4)).
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.
Roeder et al., New York City, United States. In Genes Dev, Nov 2015
Here we demonstrate that the histone demethylase JMJD1C functions as a coactivator for RUNX1-RUNX1T1 and is required for its transcriptional program.
Mutations in JMJD1C are involved in Rett syndrome and intellectual disability.
Esteller et al., Barcelona, Spain. In Genet Med, Aug 2015
Herein, we aimed to identify whether mutations in the candidate histone demethylase JMJD1C (jumonji domain containing 1C) are implicated in these disorders.
Platelet count mediates the contribution of a genetic variant in LRRC16A to ARDS risk.
Christiani et al., In Chest, Mar 2015
A prior meta-analysis identified five loci for platelet count (PLT): BAD, LRRC16A, CD36, JMJD1C, and SLMO2.
Pluripotency transcription factor Oct4 mediates stepwise nucleosome demethylation and depletion.
Tantin et al., Salt Lake City, United States. In Mol Cell Biol, Mar 2015
Upon binding DNA, Oct4 recruits the histone lysine demethylase Jmjd1c.
Expression pattern of JMJD1C in oocytes and its impact on early embryonic development.
Zhang et al., Changchun, China. In Genet Mol Res, 2014
On screening, the Jumonji domain containing 1C (JMJD1C) gene had the highest level of expression and hence was used for subsequent experiments.
The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sites.
Ayoub et al., Haifa, Israel. In Cell Cycle, 2014
Finally, we discuss the recruitment mode and the biological functions of additional lysine demethylases including KDM4B, KDM5B, JMJD1C, and LSD1 in DNA damage response.
Novel somatic and germline mutations in intracranial germ cell tumours.
Lau et al., Houston, United States. In Nature, 2014
We report significant enrichment of novel and rare germline variants in JMJD1C, which codes for a histone demethylase and is a coactivator of the androgen receptor, among Japanese IGCT patients.
Genomic scan reveals loci under altitude adaptation in Tibetan and Dahe pigs.
Ma et al., Beijing, China. In Plos One, 2013
Totally, we identified 12 specific selective genes (CCBE1, F2RL1, AGGF1, ZFPM2, IL2, FGF5, PLA2G4A, ADAMTS9, NRBF2, JMJD1C, VEGFC and ADAM19) for TBP and six (OGG1, FOXM, FLT3, RTEL1, CRELD1 and RHOG) for DHP.
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Kooner et al., London, United Kingdom. In Nat Genet, 2011
We identified 69 candidate genes, including genes involved in biliary transport (ATP8B1 and ABCB11), glucose, carbohydrate and lipid metabolism (FADS1, FADS2, GCKR, JMJD1C, HNF1A, MLXIPL, PNPLA3, PPP1R3B, SLC2A2 and TRIB1), glycoprotein biosynthesis and cell surface glycobiology (ABO, ASGR1, FUT2, GPLD1 and ST3GAL4), inflammation and immunity (CD276, CDH6, GCKR, HNF1A, HPR, ITGA1, RORA and STAT4) and glutathione metabolism (GSTT1, GSTT2 and GGT), as well as several genes of uncertain or unknown function (including ABHD12, EFHD1, EFNA1, EPHA2, MICAL3 and ZNF827).
Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Zhou et al., New York City, United States. In Nature, 2010
Whereas the interaction with H3 is promoted by acetylation at lysine 14, it is inhibited by methylation at lysine 4, and these opposing influences are important during transcriptional activation of the mouse DPF3b target genes Pitx2 and Jmjd1c.
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.
Becker et al., Framingham, United States. In Nat Genet, 2010
JMJD1C (P=1.6x10(-8)),
Comparative integromics on JMJD1C gene encoding histone demethylase: conserved POU5F1 binding site elucidating mechanism of JMJD1C expression in undifferentiated ES cells and diffuse-type gastric cancer.
Katoh et al., Japan. In Int J Oncol, 2007
Human JMJD1C variant 2 with TRI8H1, TRI8H2, and JmjC domains showed 85.7% total-amino-acid identity with mouse Jmjd1c.
A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the AR.
Obendorf et al., Jena, Germany. In Arch Biochem Biophys, 2007
the discovery of a new Receptors, Androgen coactivator which belongs to the JmjC containing enzyme family as a novel variant of JMJD1C
Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism.
Devriendt et al., Leuven, Belgium. In Eur J Hum Genet, 2007
TRIP8 gene codes for a protein predicted to be a transcriptional regulator associated with nuclear thyroid hormone receptors. Positional candidate gene for autism.
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