ABCG2: the molecular mechanisms of urate secretion and gout.
Baltimore, United States. In Am J Physiol Renal Physiol, Oct 2015
JAMA 300: 924-932, 2008; Wang J, Qin T, Chen J, Li Y, Wang L, Huang H, Li J. PLoS One 9: e114259, 2014; Zhu P, Liu Y, Han L, Xu G, Ran JM.
Tight Junctions Go Viral!
Ecatepec, Mexico. In Viruses, Sep 2015
For example, TJ proteins such as JAM-A or some members of the claudin family of proteins are used by members of the Reoviridae family and hepatitis C virus as receptors or co-receptors during their entry into their host cells.
Architecture of tight junctions and principles of molecular composition.
Bethesda, United States. In Semin Cell Dev Biol, 2014
In general the architecture can be conceptualized into compartments with the transmembrane barrier proteins (claudins, occludin, JAM-A, etc.), linked to peripheral scaffolding proteins (such as ZO-1, afadin, MAGI1, etc.) which are in turned linked to actin and microtubules through numerous linkers (cingulin, myosins, protein 4.1, etc.).
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.
London, United Kingdom. In Nature, 2010
Examination of the genes on the segment of Hsa21 in Tc1 mice identified putative anti-angiogenic genes (ADAMTS1and ERG) and novel endothelial cell-specific genes, never previously shown to be involved in angiogenesis (JAM-B and PTTG1IP), that, when overexpressed, are responsible for inhibiting angiogenic responses to VEGF.