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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Integrator complex subunit 4

INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: HAX-1, SmaI
Papers on INTS4
The integrator complex is required for integrity of Cajal bodies.
Shibahara et al., Mishima, Japan. In J Cell Sci, 2012
Depletion of INTS4, an integrator complex subunit, abrogated 3'-end processing of snRNA.
Characterization of KIAA0513, a novel signaling molecule that interacts with modulators of neuroplasticity, apoptosis, and the cytoskeleton.
McInnes et al., New York City, United States. In Brain Res, 2006
KIAA0513 interacts with KIBRA, HAX-1, and INTS4, which also interact with proteins involved in neuroplasticity, apoptosis, and cytoskeletal regulation.
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