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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Integrin, beta 8

integrin beta8
Top mentioned proteins: PCNA, CAN, Adenylate Cyclase, PAI-1, HAD
Papers on integrin beta8
[Effect of integrin beta8 on neuronal apoptosis after hypoxia ischemia in astrocyte/neuron co-culture system].
Mu et al., In Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2014
OBJECTIVE: To observe the effect of integrin beta8 on the neuronal apoptosis after hypoxia ischemia (HI) in astrocyte/neuron co-culture system.
Downregulation of MiR-93 expression reduces cell proliferation and clonogenicity of HepG2 cells.
Lin et al., Wuhan, China. In Hepatogastroenterology, 2012
The mRNA and protein levels of transforming growth factor-beta type II receptor (TGFBR2) and integrin beta8 (ITGB8)were evaluated by RT-PCR and western blot analysis.
Transcription of the transforming growth factor beta activating integrin beta8 subunit is regulated by SP3, AP-1, and the p38 pathway.
Nishimura et al., San Francisco, United States. In J Biol Chem, 2010
Recent studies have suggested roles for integrin beta8 in the pathogenesis of chronic obstructive pulmonary disease, brain arteriovenous malformations, and select cancers (Araya, J., Cambier, S., Markovics, J. A., Wolters, P., Jablons, D., Hill, A., Finkbeiner, W., Jones, K., Broaddus, V. C., Sheppard, D., Barzcak, A., Xiao, Y., Erle, D. J., and Nishimura, S. L. (2007) J. Clin.
Reduced expression of integrin alphavbeta8 is associated with brain arteriovenous malformation pathogenesis.
Nishimura et al., San Francisco, United States. In Am J Pathol, 2010
We determined that beta8 protein expression in perivascular astrocytes was reduced in human BAVM lesional tissue compared with controls and that the angiogenic response to focal vascular endothelial growth factor stimulation in adult mouse brains with local Cre-mediated deletion of itgb8 and smad4 led to vascular dysplasia in newly formed blood vessels.
Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice.
Cooke et al., Cambridge, United Kingdom. In Eur J Immunol, 2009
Our studies show that SEA can have a direct effect on CD4(+) T cells increasing expression of TGF-beta, integrin beta8 and galectins.
Vascular development of the brain requires beta8 integrin expression in the neuroepithelium.
Reichardt et al., San Francisco, United States. In J Neurosci, 2005
We showed previously that loss of the integrin beta8 subunit, which forms alphavbeta8 heterodimers, results in abnormal vascular development in the yolk sac, placenta, and brain.
[Expression of keratinocyte basement membrane related genes during the process of re-epithelialization of burn wound in scalded rats].
Xu et al., Shanghai, China. In Zhonghua Shao Shang Za Zhi, 2005
RESULTS: The expression of laminin (LN) gamma 1 (2.068) and integrin beta8 (2.200) was up-regulated on 3 PSD compared with that in control.
Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells.
Soria et al., Rouen, France. In Cell Signal, 2003
They could contribute to the inhibition of both cell proliferation (down-regulation of cyclin D1, PCNA, c-myc and up-regulation p21(Waf1), p19(INK4d), integrin beta8) and cell invasion, either directly (decrease in u-PA, MMP-9, u-PAR, PAI-1 and increase in anti-oncogenes Wnt-5a and H-cadherin) or indirectly by stimulating an anti-angiogenic gene (thrombospondin-2).
Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
Maher et al., Birmingham, United Kingdom. In Cancer Res, 2002
In addition, six novel targets were detected: cyclin D1 (CCND1), cell division protein kinase 6, collagen VIII alpha 1 subunit, CD59 glycoprotein precursor, integrin beta8, and interleukin 6 precursor IFN-beta2.
beta8 integrins are required for vascular morphogenesis in mouse embryos.
Reichardt et al., San Francisco, United States. In Development, 2002
In order to assess the in vivo function of integrins containing the beta8 subunit, we have generated integrin beta8-deficient mice.
A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth.
Nishimura et al., San Francisco, United States. In Cancer Res, 2001
On the basis of our findings that the integrin beta8 subunit is expressed in airway epithelial cells and is absent in lung cancers, we investigated the role and mechanism of the integrin alphavbeta8 in mediating growth inhibition.
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