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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Insulin-like growth factor binding protein 2a

IGFBP-2, Insulin-Like Growth Factor Binding Protein 2, igfbp-2a, IGFBP-2b
Top mentioned proteins: Insulin, Insulin-Like Growth Factor I, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor II, Insulin-Like Growth Factor Binding Protein 1
Papers on IGFBP-2
The Beneficial Impact of Antidepressant Drugs on Prenatal Stress-Evoked Malfunction of the Insulin-Like Growth Factor-1 (IGF-1) Protein Family in the Olfactory Bulbs of Adult Rats.
Basta-Kaim et al., Kraków, Poland. In Neurotox Res, Feb 2016
The mRNA expression of IGF-1 and IGF-1 receptor (IGF-1R) and the protein level of IGF-1 and its phosphorylation, as well as the concentrations of IGF-binding proteins (IGFBP-2, -4, -3, and -6), were measured in OBs before and after chronic imipramine, fluoxetine, or tianeptine administration.
Relevance of fruits, vegetables and flavonoids from fruits and vegetables during early life, mid-childhood and adolescence for levels of insulin-like growth factor (IGF-1) and its binding proteins IGFBP-2 and IGFBP-3 in young adulthood.
Buyken et al., Dortmund, Germany. In Br J Nutr, Feb 2016
We used data from Dortmund Nutritional and Anthropometric Longitudinally Designed Study participants to analyse prospective associations between FV, fruit intake and flavonoid intake from FV (FlavFV) with IGF-1 and its binding proteins IGFBP-2 and IGFBP-3.
IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation.
Clemmons et al., Nanjing, China. In J Bone Miner Res, Feb 2016
UNASSIGNED: Insulin like growth factor I (IGF-I) and insulin like growth factor binding protein-2 (IGFBP-2) function coordinately to stimulate AKT and osteoblast differentiation.
Cord blood insulin-like growth factor (IGF)-1, IGF-binding proteins and adiponectin, and birth size in offspring of women with mild gestational diabetes.
Sumazaki et al., Tsukuba, Japan. In Early Hum Dev, Feb 2016
No differences in cord blood free IGF-1, IGFBP-1, IGFBP-2 or AdipoQ levels were observed between the mGDM and NGT groups.
Transcriptome analysis reveals the molecular mechanisms underlying growth superiority in a novel grouper hybrid (Epinephelus fuscogutatus♀ × E. lanceolatus♂).
Zhang et al., Guangzhou, China. In Bmc Genet, Dec 2015
Further analysis showed the expressions of GnRH1and GnRH3 in the brain, and GH/IGF axis related genes such as IGF-1, IGF-2b, IGFBP-1, IGFBP-2, IGFBP-4 and IGFBP-5a in the liver of the hybrid F1 were significantly up-regulated, which is in accordance with the growth superiority of hybrid grouper.
IGFBP-2 as a novel biomarker for disease activity and renal pathology changes in lupus nephritis.
Wu et al., Dallas, United States. In Clin Exp Immunol, Dec 2015
The objective of this study is to validate serum IGFBP-2 as a novel biomarker for clinical disease and renal pathology in LN. 85 biopsy-proven lupus nephritis patients, 18 CKD patients and 20 healthy controls were recruited for ELISA testing of serum IGFBP-2 levels.
Physiology and pathophysiology of IGFBP-1 and IGFBP-2 - Consensus and dissent on metabolic control and malignant potential.
Russo et al., Germany. In Best Pract Res Clin Endocrinol Metab, Oct 2015
IGFBP-1 and IGFBP-2 are suppressed by growth hormone and therefore represent less prominent members of the IGFBP family when compared to IGFBP-3 that carries most of the IGFs during circulation under normal conditions in humans in vivo.
IGFBP-2/PTEN: A critical interaction for tumours and for general physiology?
Holly et al., Bristol, United Kingdom. In Growth Horm Igf Res, Jun 2015
IGFBP-2 is an important modulator of IGF availability and activity.
IGFBP-2: The dark horse in metabolism and cancer.
Werther et al., Australia. In Cytokine Growth Factor Rev, Jun 2015
Among all the IGFBPs, IGFBP-2 has been implicated in the regulation of IGF activity in the nervous system, peripheral tissue and organs.
Platelet-derived growth factor (PDGF)-AA/AB in human serum are potential indicators of the proliferative capacity of human synovial mesenchymal stem cells.
Sekiya et al., Tokyo, Japan. In Stem Cell Res Ther, 2014
RESULTS: Compared with rapid preparation serum, slow preparation serum resulted in a significantly higher total colony number and twofold higher expression levels of nine proteins (angiopoietin-1, BDNF, EGF, ENA-78, IGFBP-2, platelet-derived growth factor (PDGF)-AA, PDGF-AB/BB, RANTES and TfR).
Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates.
Brenmoehl et al., Germany. In Front Endocrinol (lausanne), 2013
IGFBP-2 (1) has been described as a brain tumor oncogene (2) and is widely expressed in cancers from different origins (3-8).
Artificial Neural Networks, and Evolutionary Algorithms as a systems biology approach to a data-base on fetal growth restriction.
Grossi et al., Parma, Italy. In Prog Biophys Mol Biol, 2013
These analyses identified the importance of the biochemical variables IL-6, IGF-II and IGFBP-2 protein concentrations in placental lysates, and offered a new insight into placental markers of fetal growth within the IGF and cytokine systems, confirmed they had relationships and offered a critical assessment of studies previously performed.
Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.
Duan et al., Ann Arbor, United States. In Plos One, 2007
The identification and characterization of two IGFBP-2 genes in zebrafish and four other teleost fish, is reported.
Targeted knockdown of insulin-like growth factor binding protein-2 disrupts cardiovascular development in zebrafish embryos.
Duan et al., Ann Arbor, United States. In Mol Endocrinol, 2005
IGFBP-2 is required for general embryonic development and growth and plays a local role in regulating vascular development in a model vertebrate organism.
Insulin-like growth factor signaling in fish.
Bern et al., Ann Arbor, United States. In Int Rev Cytol, 2004
The igfbp2(30-32kDa)is similarities to mammalian size.
Cellular actions of the insulin-like growth factor binding proteins.
Baxter et al., Sydney, Australia. In Endocr Rev, 2002
IGFBP-2, -3, -5, and -6 have heparin-binding domains and can bind glycosaminoglycans.
Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis.
Slawin et al., Houston, United States. In J Clin Oncol, 2002
MATERIAL AND METHODS: Plasma levels of IGF-I, IGFBP-2, and IGFBP-3 were measured preoperatively in 120 consecutive patients who underwent radical prostatectomy for clinically localized disease, postoperatively in 51 of these patients, in 44 healthy men, in 19 patients with metastases to regional lymph nodes, and in 10 patients with bone metastases.
Growth hormone and the insulin-like growth factor system in myogenesis.
Coolican et al., Syracuse, United States. In Endocr Rev, 1996
Other myoblasts also secrete IGFBP-2.
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