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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Interferon-induced protein 44-like

IFI44L, C1orf29
Top mentioned proteins: MxA, RIG-G, STAT1, ISG15, CAN
Papers on IFI44L
IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus.
Lu et al., Changsha, China. In Ann Rheum Dis, Feb 2016
METHODS: IFI44L promoter methylation was examined using DNA samples from a discovery set including 377 patients with SLE, 358 healthy controls (HCs) and 353 patients with rheumatoid arthritis (RA).
Genome-wide transcriptional profiling reveals that HIV-1 Vpr differentially regulates interferon-stimulated genes in human monocyte-derived dendritic cells.
Aida et al., Wako, Japan. In Virus Res, Nov 2015
The differential expression profiles of select genes involved in innate immune responses (interferon-stimulated genes [ISGs]), including MX1, MX2, ISG15, ISG20, IFIT1, IFIT2, IFIT3, IFI27, IFI44L, and TNFSF10, were validated by real-time quantitative PCR; the results were consistent with the microarray data.
Identification of potential genomic biomarkers for Sjögren's syndrome using data pooling of gene expression microarrays.
Altorok et al., Toledo, United States. In Rheumatol Int, May 2015
An LDA by leave-one-out cross-validation method identified 19 genes (EPSTI1, IFI44, IFI44L, IFIT1, IFIT2, IFIT3, MX1, OAS1, SAMD9L, PSMB9, STAT1, HERC5, EV12B, CD53, SELL, HLA-DQA1, PTPRC, B2M, and TAP2) with highest classification accuracy rate (95.7 %).
Type I interferon related genes are common genes on the early stage after vaccination by meta-analysis of microarray data.
Liang et al., Beijing, China. In Hum Vaccin Immunother, 2014
Six of which were type I interferon (IFN) related genes, including LY6E, MX1, OAS3, IFI44L, IFI6 and IFITM3.
Common variants associated with general and MMR vaccine-related febrile seizures.
Hviid et al., Copenhagen, Denmark. In Nat Genet, 2014
Two loci were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 × 10(-12) versus controls, P = 1.2 × 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (rs1318653: P = 9.6 × 10(-11) versus controls, P = 1.6 × 10(-9) versus MMR-unrelated febrile seizures).
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
Kendler et al., New York City, United States. In Mol Psychiatry, 2014
In our case-control analysis, we identify five previously identified regions reaching genome-wide significance (CACNA1C, IFI44L, MHC, TRANK1 and MAD1L1) and a novel locus near PIK3C2A.
MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjogren's syndrome.
Versnel et al., Rotterdam, Netherlands. In Ann Rheum Dis, 2014
The IFNscore, a measure for total type I IFN bioactivity, was calculated using expression values of the IFN type I signature genes--IFI44, IFI44L, IFIT3, LY6E and MX1--in CD14 monocytes, determined by real-time quantitative PCR.
Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer.
Puig et al., Barcelona, Spain. In Oncotarget, 2014
As a result, we found that 1535 transcripts were deregulated in CDKN2A mutated cells, with over-expression of immunity-related genes (HLA-DPB1, CLEC2B, IFI44, IFI44L, IFI27, IFIT1, IFIT2, SP110 and IFNK) and down-regulation of genes playing a role in the Notch signaling pathway.
Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.
Sawalha et al., Toledo, United States. In Arthritis Rheumatol, 2014
The interferon signature pathway was represented by hypomethylation of STAT1, IFI44L, USP18, and IFITM1.
LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.
Yang et al., Boston, United States. In Plos One, 2013
LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L, a gene that has been implicated in the cellular response to Type I interferons.
HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages.
Aida et al., Wako, Japan. In Plos One, 2013
The differential expression profiles of select interferon-stimulated genes (ISGs) and genes involved in the innate immune response, including STAT1, IRF7, MX1, MX2, ISG15, ISG20, IFIT1, IFIT2, IFIT3, IFI27, IFI44L, APOBEC3A, DDX58 (RIG-I), TNFSF10 (TRAIL), and RSAD2 (viperin) were confirmed by real-time quantitative PCR and were consistent with the microarray data.
A non-invasive diagnosis of histiocytic necrotizing lymphadenitis by means of gene expression profile analysis of peripheral blood mononuclear cells.
Hara et al., Fukuoka, Japan. In J Clin Immunol, 2013
The top five up-regulated genes (IFI44L, CXCL10, GBP1, EPSTI1 and IFI27) in HNL were interferon-induced genes (ISGs).
The physiologic increase in expression of some type I IFN-inducible genes during pregnancy is not associated with improved disease activity in pregnant patients with rheumatoid arthritis.
Förger et al., Berlin, Germany. In Transl Res, 2013
Peripheral blood mononuclear cells were evaluated using quantitative real-time polymerase chain reaction for type I IFN-inducible genes (IFI 35, IFI44, IFI44L, IFIT3, OAS1, and Siglec1) in patients with RA and healthy women during and after pregnancy as well as in nonpregnant controls.
Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.
Sawalha et al., Ann Arbor, United States. In J Autoimmun, 2013
We observed significant hypomethylation in interferon-regulated genes in naïve CD4+ T cells from lupus patients, including IFIT1, IFIT3, MX1, STAT1, IFI44L, USP18, TRIM22 and BST2, suggesting epigenetic transcriptional accessibility in these genetic loci.
A diverse range of gene products are effectors of the type I interferon antiviral response.
Rice et al., New York City, United States. In Nature, 2011
Broadly acting effectors included IRF1, C6orf150 (also known as MB21D1), HPSE, RIG-I (also known as DDX58), MDA5 (also known as IFIH1) and IFITM3, whereas more targeted antiviral specificity was observed with DDX60, IFI44L, IFI6, IFITM2, MAP3K14, MOV10, NAMPT (also known as PBEF1), OASL, RTP4, TREX1 and UNC84B (also known as SUN2).
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