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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

HUS1 checkpoint homolog b

The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Hus1, rad1, PCNA, ACID, Rad9B
Papers on HUS1B
Differential susceptible loci expression in keloid and hypertrophic scars in the Chinese Han population.
Yan et al., Beijing, China. In Ann Plast Surg, 2015
HUS1B) are new potential SNPs associated with KD formation, especially closely related to tumor behaviors as KD is, whereas rs141156594 (18q22.2,
Clamping down on mammalian meiosis.
Lieberman et al., New York City, United States. In Cell Cycle, 2013
Based on these studies and the high-level expression of the paralogous proteins RAD9B and HUS1B in testis, we propose a model in which multiple alternative 9-1-1 clamps function during mammalian meiosis to ensure genome maintenance in the germline.
Identification and characterization of RAD9B, a paralog of the RAD9 checkpoint gene.
Karnitz et al., Rochester, United States. In Genomics, 2003
In addition, we have also shown that RAD9 and RAD9B interact with the HUS1 paralog, HUS1B.
Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1.
Lieberman et al., New York City, United States. In Genomics, 2002
HUS1B directly interacts with RAD1, but not RAD9 or HUS1, whereas HUS1 can bind RAD1, RAD9, and another molecule of HUS1, suggesting that HUS1B cannot simply substitute for HUS1 in the complex.
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