Papers on
HLTF
Epigenetic profiling of gallbladder cancer and gall stone diseases: Evaluation of role of tumour associated genes.Tiwari et al., Gwalior, India. In Gene, Mar 2016
MATERIALS AND METHODS: Methylation specific PCR for seven tumour associated genes, viz., MASPIN, 14-3-3 sigma gene, THBS1, FLNC, HLTF, COX-2 and SOCS1, was performed in 50 gallbladder cancer (GBC), 30 gall stone diseases (GSD) and their respective adjacent control tissues.
Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Haracska et al., Szeged, Hungary. In Nucleic Acids Res, Jan 2016
Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-binding, PCNA-polyubiquitin-ligase, and dsDNA-translocase activities, respectively.
SMARCAL1 maintains telomere integrity during DNA replication.Cortez et al., Nashville, United States. In Proc Natl Acad Sci U S A, Jan 2016
The SMARCAL1 (SWI/SNF related, matrix-associated, actin-dependent, regulator of chromatin, subfamily A-like 1) DNA translocase is one of several related enzymes, including ZRANB3 (zinc finger, RAN-binding domain containing 3) and HLTF (helicase-like transcription factor), that are recruited to stalled replication forks to promote repair and restart replication.
Identification of distal enhancers for Six2 expression in pronephros.Ochi et al., Yamagata, Japan. In Int J Dev Biol, 2014
Motif analysis of transcription factors combined with phylogenetic footprinting revealed the enrichment of putative T-cell factor (Tcf)-, Hox-, and SWI/SNF complex helicase-like transcription factor (Hltf)- and AT-rich interactive domain 3A (Arid3a)-binding motif sequences in these enhancers.
Genetics of human iris colour and patterns.Larsson et al., Brisbane, Australia. In Pigment Cell Melanoma Res, 2009
A model is presented whereby this SNP, serving as a target site for the SWI/SNF family member HLTF, acts as part of a highly evolutionary conserved regulatory element required for OCA2 gene activation through chromatin remodelling.
After chromatin is SWItched-on can it be RUSHed?Chilton et al., Lubbock, United States. In Mol Cell Endocrinol, 1999
The SWI/SNF-related family of RUSH proteins which includes RUSH-1alpha and beta, hHLTF, HIP116, Zbu1, P113, and the transcription factor RUSH-1alpha isolog has been implicated as a highly conserved DNA binding site-specific ATPase.