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Remodeling and spacing factor 1

hepatitis B virus X-associated protein, Rsf-1, HBXAP, remodeling and spacing factor, P325
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011] (from NCBI)
Top mentioned proteins: AIP, CAN, aryl hydrocarbon receptor, Hsp90, Histone
Papers on hepatitis B virus X-associated protein
The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores.
Cho et al., Suwŏn, South Korea. In Nat Commun, 2014
The chromatin remodeller RSF1 tightly associates with centromere proteins, but its mitotic function is unknown.
Prognostic value of rsf-1/hbxap in human solid tumors: a meta-analysis of cohort studies.
He et al., Zhanjiang, China. In Int J Clin Exp Med, 2014
PURPOSE: Recent studies have investigated remodeling and spacing factor 1 (Rsf-1) as a molecular marker in various solid tumors.
Causal variation in yeast sporulation tends to reside in a pathway bottleneck.
Cohen et al., Saint Louis, United States. In Plos Genet, 2014
Through crosses between natural isolates of yeast, we demonstrate that the specific causal nucleotides responsible for differences in sporulation efficiencies reside not only in IME1 but also in the genes that surround IME1 in the signaling pathway, including RME1, RSF1, RIM15, and RIM101.
Rsf-1 overexpression serves as a prognostic marker in human hepatocellular carcinoma.
Li et al., Shenyang, China. In Tumour Biol, 2014
Rsf-1 (HBXAP) was recently reported to be overexpressed in various cancers and associated with the malignant behavior of cancer cells.
Rsf-1 overexpression in human prostate cancer, implication as a prognostic marker.
He et al., Shenyang, China. In Tumour Biol, 2014
Rsf-1 (HBXAP) was recently reported to be overexpressed in various cancers and associated with the malignant behavior of cancer cells.
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins.
Lowndes et al., Galway, Ireland. In Plos Biol, 2014
Here we identify a biochemical interaction between ATM and RSF1 and we characterise the role of RSF1 in this response.
RSF1 is a positive regulator of NF-κB-induced gene expression required for ovarian cancer chemoresistance.
Choi et al., Seoul, South Korea. In Cancer Res, 2014
Overexpression or amplification of the RSF1 gene has been associated with poor prognosis in various human cancers, including ovarian cancer.
Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining.
van Attikum et al., Leiden, Netherlands. In Cell Cycle, 2013
It forms distinct chromatin remodeling complexes with several non-canonical subunits, including the remodeling and spacing factor 1 (RSF1) protein.
Quantification of serum HBXAP DNA in lung cancer patients by quantitative fluorescent polymerase chain reaction.
Luo et al., Chongqing, China. In Mol Biol Rep, 2013
Hepatitis B virus x associated protein (HBXAP), as a subunit of chromatin remodeling and spacing factor, plays a critical role in cancer development through gene amplification.
Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.
Crawford et al., Tiffin, United States. In Plos One, 2012
Our most significant AM association was upstream of RSF1, a gene implicated in ovarian and breast cancers (rs11604207, p = 1.6×10⁻⁰⁶).
RSF1 and not cyclin D1 gene amplification may predict lack of benefit from adjuvant tamoxifen in high-risk pre-menopausal women in the MA.12 randomized clinical trial.
Basik et al., Montréal, Canada. In Plos One, 2012
The RSF1 (remodeling and spacing factor 1) gene is frequently co-amplified with CCND1 on chromosome 11q.
Sporulation genes associated with sporulation efficiency in natural isolates of yeast.
Sinha et al., Mumbai, India. In Plos One, 2012
Some studies have uncovered the genetic basis of this variation and have identified the role of sporulation genes (IME1, RME1) and sporulation-associated genes (FKH2, PMS1, RAS2, RSF1, SWS2), as well as non-sporulation pathway genes (MKT1, TAO3) in maintaining this variation.
Rsf-1 expression in rectal cancer: with special emphasis on the independent prognostic value after neoadjuvant chemoradiation.
Chen et al., Tainan City, Taiwan. In J Clin Pathol, 2012
High-expression of Rsf-1 is associated with poor therapeutic response and adverse outcome in rectal cancer patients treated with neoadjuvant chemoradiotherapy.
Rsf-1 is overexpressed in non-small cell lung cancers and regulates cyclinD1 expression and ERK activity.
Wang et al., Shenyang, China. In Biochem Biophys Res Commun, 2012
Rsf-1 is overexpressed in non-small cell lung cancers and contributes to malignant cell growth by cyclin D1 and ERK modulation.
Associations of Rsf-1 overexpression with poor therapeutic response and worse survival in patients with nasopharyngeal carcinoma.
Li et al., Taiwan. In J Clin Pathol, 2012
Rsf-1 overexpression is common and is associated with adverse prognosticators and therapeutic response in nasopharyngeal carcinoma.
Rsf-1/HBXAP overexpression is associated with disease-specific survival of patients with gallbladder carcinoma.
Li et al., Kao-hsiung, Taiwan. In Apmis, 2011
Rsf-1 overexpression is common and associated with adverse prognosticators in gallbladder carcinomas.
Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma.
Sheu et al., Kao-hsiung, Taiwan. In Am J Pathol, 2011
our results suggest that RSF-1 up-regulation is associated with several clinicopathological features of disease aggressiveness in oral squamous cell carcinoma
Pathogenesis of ovarian cancer: clues from selected overexpressed genes.
Davidson et al., Baltimore, United States. In Future Oncol, 2009
The genes to be discussed include nuclear proteins (Notch3, HBXAP [Rsf-1], NAC1 and NFkappaB), cytoplasmic proteins (fatty acid synthase and apolipoprotein E) and cell surface/secretory proteins (mucin-4, mesothelin, claudin, HLA-G, kallikrein and folate receptor and osteopontin).
Genetic interactions between transcription factors cause natural variation in yeast.
Cohen et al., Saint Louis, United States. In Science, 2009
study shows that natural variation in sporulation efficiency between oak tree & vineyard strains is due to allelic variation between four nucleotide changes in three transcription factors: IME1, RME1 & RSF1
Requirement of RSF and FACT for transcription of chromatin templates in vitro.
Reinberg et al., United States. In Science, 1999
This factor, remodeling and spacing factor (RSF), has adenosine triphosphate-dependent nucleosome-remodeling and spacing activities.
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