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Capping protein

gsg3, F-actin capping protein alpha-3 subunit, CPalpha3
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Actin, CREM, fibrillin-1, ACID, Rab5
Papers on gsg3
Characterizing mouse male germ cell-specific actin capping protein alpha3 (CPalpha3): dynamic patterns of expression in testicular and epididymal sperm.
Tanaka et al., Ōsaka, Japan. In Asian J Androl, 2008
AIM: To characterize mouse capping protein alpha3 (CPalpha3) during spermatogenesis and sperm maturation.
[Proteomic identification of necrozoospermia-related proteins].
Lu et al., Changsha, China. In Zhonghua Nan Ke Xue, 2008
The 6 missing protein spots in the necrozoospermic map were identified as sperm protein (human, accession No. 060904), zinc finger protein 174 (AW-1), F-actin capping protein alpha-3 subunit, testis-specific inhibitor of apoptosis, death domain receptor 3 soluble form (fragment) and peptide similar to the activator of CREM in the testis.
Applying proteomic methodologies to analyze the effect of hexamethylene bisacetamide (HMBA) on proliferation and differentiation of human gastric carcinoma BGC-823 cells.
Peng et al., Xiamen, China. In Int J Biochem Cell Biol, 2004
Five distinct altered proteins were acquired by two-dimensional (2-D) PAGE and were consequently identified as ras-related protein rab-35 (Rab-35), splice truncated isoform of transmembrane protease, serine 3 (serine TADG-12), regulator of G-protein signaling 1 (RGS1), ret finger protein-like 1 (RFPL1) and F-actin capping protein alpha-3 subunit (GSG3) by analysis of mass spectrograph.
Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3).
Nishimune et al., Ōsaka, Japan. In Mol Hum Reprod, 2002
Capping protein alpha3 may play a physiologically important role in sperm architecture as well as in fertility of the human male.
Expression of a testis-specific putative actin-capping protein associated with the developing acrosome during rat spermiogenesis.
Jones et al., Cambridge, United Kingdom. In Mol Reprod Dev, 1998
The primary amino acid sequence is 90% identical to that of a previously identified testis-specific mouse protein, gsg3, both showing approximately 40% homology to the alpha subunit of somatic ACPs.
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