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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

G protein-coupled receptor 75

GPR75, WI-31133, G protein-coupled receptor 75
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002] (from NCBI)
Top mentioned proteins: V1a, Insulin, GPR, GPR18, FGD1
Papers on GPR75
Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors.
Jamil et al., India. In Mol Phylogenet Evol, 2014
Our study was able to identify potential ligand association for Class A Orphans and putative/unclassified Class A receptors with no cognate ligand information: GPR21 and GPR52 with fatty acids; GPR75 with Neuropeptide Y; GPR82, GPR18, GPR141 with N-arachidonylglycine; GPR176 with Free fatty acids, GPR10 with Tachykinin & Neuropeptide Y; GPR85 with ATP, ADP & UDP glucose; GPR151 with Galanin; GPR153 and GPR162 with Adrenalin, Noradrenalin; GPR146, GPR139, GPR142 with Neuromedin, Ghrelin, Neuromedin U-25 & Thyrotropin-releasing hormone; GPR171 with ATP, ADP & UDP Glucose; GPR88, GPR135, GPR161, GPR101with 11-cis-retinal; GPR83 with Tackykinin; GPR148 with Prostanoids, GPR109b, GPR81, GPR31with ATP & UTP and GPR150 with GnRH I & GnRHII.
DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia.
Brim et al., Washington, D.C., United States. In Epigenetics, 2014
Fifty CpG sites located within CpG islands-in genes ATXN7L1 (2), BMP3 (7), EID3 (15), GAS7 (1), GPR75 (24), and TNFAIP2 (1)-were significantly hypermethylated in tumor vs. normal tissues (P<0.05).
The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis.
Persaud et al., London, United Kingdom. In Diabetologia, 2013
AIMS/HYPOTHESIS: Chemokine (C-C motif) ligand 5 (CCL5) acts at C-C chemokine receptors (CCRs) to promote immune cell recruitment to sites of inflammation, but is also an agonist at G-protein-coupled receptor 75 (GPR75), which has very limited homology with CCRs.
RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75.
Schaller et al., Hamburg, Germany. In Br J Pharmacol, 2006
We show for the first time that RANTES activates the orphan G protein-coupled receptor 75 (GPR75).
Tails of the unexpected - an atypical receptor for the chemokine RANTES/CCL5 expressed in brain.
Pease, London, United Kingdom. In Br J Pharmacol, 2006
In the issue of the British Journal of Pharmacology accompanying this commentary, Ignatov and colleagues describe an unexpected role for the chemokine RANTES/CCL5, namely an ability to signal via the orphan G protein-coupled receptor named GPR75.
Evaluation of the G protein coupled receptor-75 (GPR75) in age related macular degeneration.
Weber et al., W├╝rzburg, Germany. In Br J Ophthalmol, 2001
METHODS: Northern blot and RT-PCR analyses confirmed preferential retinal expression of the gene, which encodes a G protein coupled receptor, GPR75.
Cloning and characterization of a novel orphan G-protein-coupled receptor localized to human chromosome 2p16.
Gregory-Evans et al., London, United Kingdom. In Biochem Biophys Res Commun, 1999
We have determined the full-length coding sequence and genomic structure of a gene corresponding to the anonymous expressed sequenced tag, WI-31133.
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