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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Trace amine associated receptor 3

GPR58, TAAR2, GPR57, GM225, trace amine-associated receptor 2
Top mentioned proteins: putative neurotransmitter receptor, Rhodopsin, SET, GPR87, CAN
Papers on GPR58
Constitutive Activity among Orphan Class-A G Protein Coupled Receptors.
Aronstam et al., Rolla, United States. In Plos One, 2014
Five patterns of activity were noted: 1) inhibition under both baseline and forskolin stimulated expression (GPR15, GPR17, GPR18, GPR20, GPR25, GPR27, GPR31, GPR32, GPR45, GPR57, GPR68, GPR83, GPR84, GPR132, GPR150, GPR176); 2) no effect on baseline expression, but inhibition of forskolin stimulated expression (GPR4, GPR26, GPR61, GPR62, GPR78, GPR101, GPR119); 3) elevation of baseline signaling coupled with inhibition of forskolin stimulated expression (GPR6, GPR12); 4) elevation of baseline signaling without inhibition of forskolin stimulated expression (GPR3, GPR21, GPR52, GPR65); and 5) no effect on expression (GPR1, GPR19, GPR22, GPR34, GPR35, GPR39, GPR63, GPR82, GPR85, GPR87).
Incentive loss and hippocampal gene expression in inbred Roman high- (RHA-I) and Roman low- (RLA-I) avoidance rats.
Torres et al., JaƩn, Spain. In Behav Brain Res, 2013
Microarray analysis of these hippocampi showed that four differentially-expressed, and qRT-PCR-validated genes (TAAR2, THAP1, PKD2L1, NANOS), have relevance for brain function and behavior, including schizophrenia, depression, anxiety, and drug addiction, thus showing the usefulness of Roman strains as a genetic model for research on the neurogenetic basis of frustration.
Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2.
Krautwurst et al., Freising, Germany. In J Leukoc Biol, 2013
Here, we report the functional expression of TAAR1 and its closest relative TAAR2 in blood PMN and T and B cells.
Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice.
Tokita et al., Tsukuba, Japan. In Cell Tissue Res, 2009
In contrast, GPR112, trace amine-associated receptor (TAAR) 1, TAAR2, and GPRC5A mRNAs were preferentially expressed in the mucosal layer, suggesting their potential roles in the regulation of secretion, immunity, and epithelial homeostasis.
International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.
Davenport et al., Cambridge, United Kingdom. In Pharmacol Rev, 2009
In humans, a further five genes are thought to encode functional receptors (TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9).
Biogenic Trace Amine-Associated Receptors (TAARS) are encoded in avian genomes: evidence and possible implications.
Kempenaers et al., Starnberg, Germany. In J Hered, 2008
Our results suggest that a minimum of 3 TAAR paralogues are encoded in the G. gallus genome and that these are putative orthologues of the human/mouse genes TAAR1, TAAR2, and TAAR5.
A second class of chemosensory receptors in the olfactory epithelium.
Buck et al., Seattle, United States. In Nature, 2006
Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines.
Expression analysis of secreted and cell surface genes of five transformed human cell lines and derivative xenograft tumors.
Chin et al., Menlo Park, United States. In Bmc Genomics, 2004
These included late angiogenic, morphogenic and extracellular matrix genes such as ANGPTL4, COL1A1, GP2, GPR57, LAMB3, PCDHB9 and PTGER3.
Elusive amines and cluster headache: mutational analysis of trace amine receptor cluster on chromosome 6q23.
Bussone et al., Milano, Italy. In Neurol Sci, 2004
We evaluated two families with CH by linkage analysis to 6q23 region and the mutation scanning of the TAR 1, TAR 3, TAR 4, TAR 5, PNR and GPR58 genes by denaturing high liquid chromatography is in progress in 16 familial cases.
A locus for simple pure febrile seizures maps to chromosome 6q22-q24.
LeGuern et al., Paris, France. In Brain, 2002
Sequence analysis excluded the implication of five candidate genes [A kinase anchoring protein 18 (AKAP18), syntaxin 7, putative neurotransmitter receptor (PNR), G protein receptor 57 (GPR57) and G protein receptor 58 (GPR58)] in the interval based on function.
Discovery and mapping of ten novel G protein-coupled receptor genes.
O'Dowd et al., Toronto, Canada. In Gene, 2001
GPR101 demonstrated only distant identities with other GPCR genes and GPR102 shared identities with GPR57, GPR58 and PNR (35-42% in the TM regions).
Synthetic glycopeptide-based delivery systems for systemic gene targeting to hepatocytes.
Rolland et al., The Woodlands, United States. In Pharm Res, 2000
or tri-galactosylated lipopeptide (GM246.3) in the presence of an endosomolytic peptide (GM225.1)
Cloning and characterization of additional members of the G protein-coupled receptor family.
Marchese et al., Toronto, Canada. In Biochim Biophys Acta, 2000
Based on shared sequence identities, the receptor encoded by GPR57 was predicted to belong to a novel subfamily of GPCRs together with GPR58 (a.k.a.
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