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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

G protein-coupled receptor 32

Top mentioned proteins: ACID, CMKLR1, GPCR, V1a, miR
Papers on GPR32
Constitutive Activity among Orphan Class-A G Protein Coupled Receptors.
Aronstam et al., Rolla, United States. In Plos One, 2014
Five patterns of activity were noted: 1) inhibition under both baseline and forskolin stimulated expression (GPR15, GPR17, GPR18, GPR20, GPR25, GPR27, GPR31, GPR32, GPR45, GPR57, GPR68, GPR83, GPR84, GPR132, GPR150, GPR176); 2) no effect on baseline expression, but inhibition of forskolin stimulated expression (GPR4, GPR26, GPR61, GPR62, GPR78, GPR101, GPR119); 3) elevation of baseline signaling coupled with inhibition of forskolin stimulated expression (GPR6, GPR12); 4) elevation of baseline signaling without inhibition of forskolin stimulated expression (GPR3, GPR21, GPR52, GPR65); and 5) no effect on expression (GPR1, GPR19, GPR22, GPR34, GPR35, GPR39, GPR63, GPR82, GPR85, GPR87).
Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1.
Sime et al., Rochester, United States. In J Immunol, 2014
We confirmed that ALX/FPR2 and GPR32, two RvD1 receptors, were expressed on human small airway epithelial cells.
Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7.
Rovati et al., Stockholm, Sweden. In Br J Pharmacol, 2014
Finally, lipoxygenase metabolites derived from ω-3 essential polyunsaturated acids, the resolvins, activate the receptors GPR32 and ChemR23.
Resolvin D1 inhibits TGF-β1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32.
Lee et al., Seoul, South Korea. In Int J Biochem Cell Biol, 2013
Resolvin D1 is known to act via ALX/FPR2 and GPR32.
Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.
Dartt et al., Boston, United States. In Mucosal Immunol, 2013
We found cross-talk between two types of G protein-coupled receptors (GPRs), as RvD1 interacts with its receptor GPR32 to block histamine-stimulated H1 receptor increases in intracellular [Ca(2+)] ([Ca(2+)]i) preventing H1 receptor-mediated responses.
1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients.
Teplow et al., Los Angeles, United States. In J Alzheimers Dis, 2012
The action of 1,25D3 depended on the nuclear vitamin D and the protein disulfide isomerase A3 receptors, whereas RvD1 required the chemokine receptor, GPR32.
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation.
Minta et al., Toronto, Canada. In Bmc Cardiovasc Disord, 2012
Also, several "nexus" genes in complex networks, including components of the multi-subunit enzyme complex involved in the terminal stages of cholesterol synthesis, microRNAs (miR-203, miR-511, miR-590-3p, miR-346*/miR- 1207-5p/miR-4763-3p), GPCR proteins (GPR1, GPR64, GPRC5A, GPR171, GPR176, GPR32, GPR25, GPR124) and signal transduction pathways, were found to be regulated.
Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat.
Serhan et al., Boston, United States. In J Immunol, 2012
We also identified proresolving receptors (i.e., ALX/FPR2, ChemR23, and GPR32) in these tissues.
Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions.
Perretti et al., London, United Kingdom. In Arterioscler Thromb Vasc Biol, 2012
The contribution of its specific receptors, the lipoxin A(4)/Annexin-A1 receptor formyl-peptide receptor 2 (FPR2/ALX) and the orphan receptor G-protein-coupled receptor 32 (GPR32) are of considerable interest.
Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs.
Im, Pusan, South Korea. In Prog Lipid Res, 2012
Furthermore, the conversions of omega-3 fatty acids to anti-inflammatory and pro-resolving resolvins and protectins and the identifications of putative target GPCRs, ChemR23, BLT₁, ALX/FPR2, and GPR32, have drawn great attention.
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.
Serhan et al., Boston, United States. In Am J Pathol, 2012
Among them, resolvin D1 (RvD1) actions are mediated by two G protein-coupled receptors (GPCRs), ALX/FPR2 and GPR32, that also regulate specific microRNAs (miRNAs) and their target genes in novel resolution circuits.
Infection regulates pro-resolving mediators that lower antibiotic requirements.
Serhan et al., Boston, United States. In Nature, 2012
RvD5 activated the RvD1 receptor, GPR32, to enhance phagocytosis.
Resolvins as new fascinating drug candidates for inflammatory diseases.
Lee, South Korea. In Arch Pharm Res, 2012
Further, there exists G protein-coupled receptor 32 (GPR32), chemokine receptor-like (CMLKLR), LTB4 receptor 1 (BLT1) and unidentified high-affinity surface binding receptors in human polymorphonuclear leukocytes (PMN).
MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits.
Serhan et al., Boston, United States. In Faseb J, 2011
In human macrophages overexpressing recombinant RvD1 receptors ALX/FPR2 or GPR32, these same miRNAs were significantly regulated (P<0.05) by RvD1 at concentrations as low as 10 nM, recapitulating the in vivo circuit.
Resolvins: natural agonists for resolution of pulmonary inflammation.
Levy et al., Boston, United States. In Prog Lipid Res, 2011
Acting as agonists at specific receptors (CMKLR1, BLT1, ALX/FPR2 and GPR32), resolvins can signal for potent counter-regulatory effects on leukocyte functions, including preventing uncontrolled neutrophil swarming, decreasing the generation of cytokines, chemokines and reactive oxygen species and promoting clearance of apoptotic neutrophils from inflamed tissues.
Resolvin D1 binds human phagocytes with evidence for proresolving receptors.
Serhan et al., Boston, United States. In Proc Natl Acad Sci U S A, 2010
results indicate that RvD1 specifically interacts with both ALX and GPR32 on phagocytes.
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