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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


GNS, N-acetylglucosamine-6-sulfatase, G6S, glucosamine-6-sulfatase
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, HAD, sulfatase, V1a
Papers on GNS
Anchoring Nanostructured Manganese Fluoride on Few-layer Graphene Nanosheets as Anode for Enhanced Lithium Storage.
Jin et al., In Acs Appl Mater Interfaces, Feb 2016
UNASSIGNED: Manganese fluoride (MnF2)/few-layer graphene nanosheets (GNS) composites are successfully prepared via a facile solvothermal method.
General Needs Satisfaction as a Mediator of the Relationship Between Ambivalence Over Emotional Expression and Perceived Social Support.
Lu et al., Houston, United States. In J Soc Psychol, Jan 2016
Thus, the current study investigated general needs satisfaction (GNS) as a potential mediator of the association between AEE and social support among 352 undergraduates.
T helper (Th)-cytokines in the urine of patients with primary glomerulonephritis treated with immunosuppressive drugs: Can they predict outcome?
Goumenos et al., Pátrai, Greece. In Cytokine, Dec 2015
BACKGROUND: Glomerulonephritides (GNs) represent common causes of chronic kidney disease associated with a wide spectrum of clinical and histological features.
Optimal Sulfur Content Study on Electrochemical Properties of Graphene Nanosheets/Single-Walled Carbon Nanotube Composite Electrodes.
Kim et al., In J Nanosci Nanotechnol, Nov 2015
Graphene nanosheets (GNS)/sulfur were synthesized by heating a mixture of GNS and elemental sulfur.
AS1411-conjugated gold nanospheres and their potential for breast cancer therapy.
Bates et al., Louisville, United States. In Oncotarget, Oct 2015
We find that the AS1411-linked gold nanospheres (AS1411-GNS) are stable in aqueous and serum-containing solutions.
Corrosion inhibition property of polyester-groundnut shell biodegradable composite.
Chitra et al., Coimbatore, India. In Ecotoxicol Environ Saf, Sep 2015
The present work is focused on the corrosion inhibition property of a polymer matrix composite produced by the use of groundnut shell (GNS) waste.
Gene network coherence based on prior knowledge using direct and indirect relationships.
Díaz-Díaz et al., Sevilla, Spain. In Comput Biol Chem, Jun 2015
Gene networks (GNs) have become one of the most important approaches for modeling biological processes.
Sanfilippo syndrome: Overall review.
Couce et al., Barakaldo, Spain. In Pediatr Int, Jun 2015
Enzyme activity of the different enzymes in blood serum, leukocytes or fibroblasts, and mutational analysis for SGSH, NAGLU, HGSNAT or GNS genes are required to confirm diagnosis and differentiate four subtypes of MPS III.
NMR structure of the myristylated feline immunodeficiency virus matrix protein.
Summers et al., Baltimore, United States. In Viruses, May 2015
Bacterial co-translational myristylation was facilitated by mutation of two amino acids near the amino-terminus of the protein (Q5A/G6S; myrMAQ5A/G6S).
Somatostatin receptor 2 and 5 expressions in gastroenteropancreatic neuroendocrine tumors in Turkey.
Cure et al., Bursa, Turkey. In Asian Pac J Cancer Prev, 2014
BACKGROUND: Gastroenteropancreatic neuroendocrine tumors (GNs) are slow growing and although their incidence has increased in recent years, they are relatively rarely seen.
The etiology of glomerulonephritis: roles of infection and autoimmunity.
Johnson et al., Seattle, United States. In Kidney Int, 2014
Rapid expansion in knowledge of the microbiome and its role in health and disease, as well as systems biology approaches to glomerular disease offer the potential to develop preventive approaches to GNs that can now be treated only with immunosuppression.
Mucopolysaccharidosis III (Sanfilippo Syndrome)- disease presentation and experimental therapies.
Heldermon et al., In Pediatr Endocrinol Rev, 2014
Sanfilippo Syndrome or Mucopolysaccharidosis Ill (MPS Ill) is a group of lysosomal storage diseases resulting from a deficiency of one of four lysosomal enzymes: Type A - heparan N-sulfatase (SGSH), Type B - a-N-acetylglucosaminidase (NAGLU), Type C - acetyl CoA a-glucosaminide acetyltransferase (HGSNAT) and Type D - N-acetylglucosamine-6-sulfatase (GNS).
Pharmaceutical applications of graphene-based nanosheets.
Oh et al., Seoul, South Korea. In Curr Pharm Biotechnol, 2013
Graphene-based nanosheets (GNS) are atomic-thickness monolayers of hexagonally arranged, graphite-derived carbon atoms that may be composed of graphene, graphene oxide, or reduced graphene oxide.
Imaging-based chemical screens using normal and glioma-derived neural stem cells.
Pollard et al., Cambridge, United Kingdom. In Biochem Soc Trans, 2010
Similar protocols proved effective in the establishment of tumour-initiating stem cell lines from the human brain tumour glioblastoma multiforme, which we termed GNS (glioma NS) cells.
Mucopolysaccharidosis type IIID: 12 new patients and 15 novel mutations.
van Diggelen et al., Rotterdam, Netherlands. In Hum Mutat, 2010
12 new patients and 15 novel mutations were identified in Mucopolysaccharidosis type IIID.
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.
Dirks et al., Cambridge, United Kingdom. In Cell Stem Cell, 2009
Significantly, glioma neural stem (GNS) cell lines from different tumors exhibit divergent gene expression signatures and differentiation behavior that correlate with specific neural progenitor subtypes.
A novel loss-of-function mutation in the GNS gene causes Sanfilippo syndrome type D.
Wollnik et al., İstanbul, Turkey. In Genet Couns, 2008
We identified the novel homozygous single base pair insertion, c.1226GinsG, which leads to a frame-shift and a premature truncation of the GNS protein (p.R409Rfs21X).
Sanfilippo syndrome type D: natural history and identification of 3 novel mutations in the GNS Gene.
Andermann et al., Brussels, Belgium. In Arch Neurol, 2007
Sanfilippo syndrome type D has 3 novel mutations in the GNS Gene.
Identification and characterisation of an 8.7 kb deletion and a novel nonsense mutation in two Italian families with Sanfilippo syndrome type D (mucopolysaccharidosis IIID).
Strisciuglio et al., London, United Kingdom. In Mol Genet Metab, 2007
A large intragenic deletion of 8723 bp encompassing exons 2 and 3 has been identified, the first large intragenic deletion to be reported in any of the four Sanfilippo subtypes. Q272X has also been found.
Sanfilippo syndrome type D: identification of the first mutation in the N-acetylglucosamine-6-sulphatase gene.
Young et al., London, United Kingdom. In J Med Genet, 2003
The Sanfilippo syndrome type D patient was found to be homozygous for a single base pair deletion (c1169delA), which will cause a frameshift and premature termination of N-acetylglucosamine-6-sulphatase.
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