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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Guanosine monophosphate reductase 2

GMP reductase 2, GMPR2, guanosine monophosphate reductase 2
Top mentioned proteins: GMP Reductase, CAN, cytokeratin, erbB-2, amphiregulin
Papers on GMP reductase 2
Characterizing and optimizing human anticancer drug targets based on topological properties in the context of biological pathways.
Li et al., Daqing, China. In J Biomed Inform, Apr 2015
Furthermore, the performance for mercaptopurine was significant: 6 known targets (ADSL, GMPR2, GMPR, HPRT1, AMPD3, AMPD2) were ranked in the top 15 and other four out of the top 15 (MAT2A, CDKN1A, AREG, JUN) have the potentialities to become new targets for cancer therapy.
Lack of expression of the proteins GMPR2 and PPARα are associated with the basal phenotype and patient outcome in breast cancer.
Green et al., Nottingham, United Kingdom. In Breast Cancer Res Treat, 2013
We have previously identified two novel genes PPARα (positive) and GMPR2 (negative) whose expression was significantly associated with BP at the transcriptome level.
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes.
Hedstrom et al., Waltham, United States. In Nat Chem Biol, 2011
A single crystal structure of human GMPR type 2 with IMP and NADPH fortuitously captures three different states, each of which mimics a distinct step in the catalytic cycle of guanosine monophosphate reductase(GMPR).
Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP.
Mao et al., Shanghai, China. In J Mol Biol, 2006
Here, we report the first crystal structure of human GMP reductase 2 (hGMPR2) in complex with GMP at 3.0 A resolution.
Diverse proteomic alterations in gastric adenocarcinoma.
Chiu et al., Hong Kong, Hong Kong. In Proteomics, 2004
Diverse regulations also occurred with proteins involved in cell proliferation and differentiation, such as GMP reductase 2 and creatine kinase B, and proteins bearing potential tumor suppressor activities, including prohibitin and selenium binding protein 1.
Purification, crystallization and preliminary X-ray studies of GMP reductase 2 from human.
Mao et al., Shanghai, China. In Acta Crystallogr D Biol Crystallogr, 2003
GMP reductase 2 from human has been expressed in Escherichia coli, purified and crystallized.
Cloning and functional characterization of GMPR2, a novel human guanosine monophosphate reductase, which promotes the monocytic differentiation of HL-60 leukemia cells.
Cao et al., Shanghai, China. In J Cancer Res Clin Oncol, 2003
GMPR2 is a novel human GMP reductase, and overexpression of GMPR2 can promote the monocytic differentiation of HL-60 leukemia cells.
NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties.
Mao et al., Shanghai, China. In Int J Biochem Cell Biol, 2002
Data suggest the existence of two distinct types of human GMP reductase molecular species, which can be used to explain the bimodal saturation curve noted with purified human erythrocyte GMP reductase.
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