New acylphloroglucinols from the leaves of Rhodomyrtus tomentosa
In Evidence-based Complementary and Alternative Medicine : eCAM, 2007
... measuring Thio-barbituric acid reacting substances (TBARS), total glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were purchased from Cayman Chemical Company, USA ...
Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes.
Obihiro, Japan. In World J Gastroenterol, Feb 2016
Antioxidant phytochemicals, such as polyphenols, regulate the expression of ALD-associated proteins and peptides, namely, catalase, superoxide dismutase, glutathione, glutathione peroxidase, and glutathione reductase.
Ferroptosis: Death by Lipid Peroxidation.
New York City, United States. In Trends Cell Biol, Jan 2016
UNASSIGNED: Ferroptosis is a regulated form of cell death driven by loss of activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and subsequent accumulation of lipid-based reactive oxygen species (ROS), particularly lipid hydroperoxides.
Biomarkers of selenium status in dogs.
Merelbeke, Belgium. In Bmc Vet Res, Dec 2015
Serum and whole blood glutathione peroxidase were also significantly lower in dogs consuming the low Se diet from weeks 6 and 8 respectively.
Nothing Boring About Boron.
Seattle, United States. In Integr Med (encinitas), Aug 2015
As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body's use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α); (6) raises levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves the brains electrical activity, cognitive performance, and short-term memory for elders; (9) influences the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD(+)); (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin's lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents.
Elucidating Compound Mechanism of Action by Network Perturbation Analysis.
New York City, United States. In Cell, Aug 2015
Finally, unknown-MoA compound analysis revealed altretamine, an anticancer drug, as an inhibitor of glutathione peroxidase 4 lipid repair activity, which was experimentally confirmed, thus revealing unexpected similarity to the activity of sulfasalazine.