gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

GAD1 glutamate decarboxylase 1 (brain, 67kDa)

glutamic acid decarboxylase
Top mentioned proteins: ACID, Rdl, HAD, Insulin, Glutamate Decarboxylase
Papers using glutamic acid decarboxylase antibodies
Interplay of parasite-driven immune responses and autoimmunity
Lehuen Agnès et al., In The Journal of Experimental Medicine, 2007
... Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice ...
Papers on glutamic acid decarboxylase
Persistence of glutamic acid decarboxylase antibody (GADA) is associated with clinical characteristics of latent autoimmune diabetes in adults: a prospective study with 3-year follow-up.
Zhou et al., Changsha, China. In Diabetes Metab Res Rev, Feb 2016
This study aimed to investigate the persistent status of glutamic acid decarboxylase antibody (GADA) in patients with LADA and its association with clinical characteristics.
Activation of Brain L-glutamate Decarboxylase 65 Isoform (GAD65) by Phosphorylation at Threonine 95 (T95).
Wu et al., Taipei, Taiwan. In Mol Neurobiol, Feb 2016
UNASSIGNED: Protein phosphorylation plays an important role in regulating soluble L-glutamic acid decarboxylase (GAD) and membrane-associated GAD activity.
The role of parvovirus B19 in the pathogenesis of autoimmunity and autoimmune disease.
Kerr, In J Clin Pathol, Jan 2016
Production of a variety of autoantibodies has been demonstrated to occur during B19 infection and these have been shown to be key to the pathogenesis of the particular disease process in a significant number of cases, for example, production of rheumatoid factor in cases of B19-associated rheumatoid arthritis and production of anti-glutamic acid decarboxylase (GAD) in patients with B19-associated type 1 diabetes mellitus.
Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs.
Guidotti et al., Chicago, United States. In Transl Psychiatry, Dec 2015
Here, we show that the behavioral deficits and the increased 5MC and 5HMC at glutamic acid decarboxylase 67 (Gad1), reelin (Reln) and brain-derived neurotrophic factor (Bdnf) promoters and the reduced expression of the messenger RNAs (mRNAs) and proteins corresponding to these genes in FC of adult PRS mice is reversed by treatment with clozapine (5 mg kg(-1) twice a day for 5 days) but not by haloperidol (1 mg kg(-1) twice a day for 5 days).
Identification of a Group of GABAergic Neurons in the Dorsomedial Area of the Locus Coeruleus.
Jiang et al., Atlanta, United States. In Plos One, Dec 2015
Channelrhodopsin (ChR2) in a tandem with the yellow fluorescent protein (YFP) was expressed in GABAergic neurons under the control of glutamic acid decarboxylase 2 (GAD2) promoter.
Effects of paternal and peripubertal stress on aggression, anxiety, and metabolic alterations in the lateral septum.
Sandi et al., Lausanne, Switzerland. In Eur Neuropsychopharmacol, Dec 2015
Proton magnetic resonance spectroscopy at 6-months, and post-mortem analysis of glutamic acid decarboxylase 67 (GAD67) at 12-months were conducted in LS.
Immunological GABAergic interactions and therapeutic applications in autoimmune diseases.
Wang et al., Toronto, Canada. In Autoimmun Rev, Nov 2015
Autoimmunity against glutamic acid decarboxylase 65 (GAD65; synthesizes GABA) occurs in T1D.
[Genetic and molecular background in autoimmune diabetes mellitus].
Buc et al., In Epidemiol Mikrobiol Imunol, Sep 2015
The most common autoantigens are insulin, glutamic acid decarboxylase 65, insuloma-associated antigen 2, and zinc transporter ZnT8.
GAD Antibodies as Key Link Between Chronic Intestinal Pseudoobstruction, Autonomic Neuropathy, and Limb Stiffness in a Nondiabetic Patient: A CARE-Compliant Case Report and Review of the Literature.
Haubrich et al., Erlangen, Germany. In Medicine (baltimore), Aug 2015
Careful interdisciplinary diagnostics excluded underlying infectious, rheumatoid, metabolic or tumorous diseases.The detection of GAD (glutamic acid decarboxylase) antibodies, however, seemed to link CIP, autonomic neuropathy, and limb stiffness and pointed at an autoimmune origin of our patient's complaints.
Rasmussen Syndrome and Other Inflammatory Epilepsies.
Cross et al., London, United Kingdom. In Semin Neurol, Jun 2015
Antibodies to intracellular antigens are less commonly seen (for example, glutamic acid decarboxylase).
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.
Pre-POINT Study Group et al., München, Germany. In Jama, May 2015
No hypoglycemia, IgE responses to insulin, autoantibodies to glutamic acid decarboxylase or insulinoma-associated antigen 2, or diabetes were observed.
Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial.
TRIGR Study Group et al., Helsinki, Finland. In Jama, 2014
Autoantibodies to insulin, glutamic acid decarboxylase, and the insulinoma-associated-2 (IA-2) molecule were analyzed using radiobinding assays and islet cell antibodies with immunofluorescence during a median observation period of 7.0 years (mean, 6.3 years).
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children.
Eisenbarth et al., München, Germany. In Jama, 2013
DESIGN, SETTING, AND PARTICIPANTS: Data were pooled from prospective cohort studies performed in Colorado (recruitment, 1993-2006), Finland (recruitment, 1994-2009), and Germany (recruitment, 1989-2006) examining children genetically at risk for type 1 diabetes for the development of insulin autoantibodies, glutamic acid decarboxylase 65 (GAD65) autoantibodies, insulinoma antigen 2 (IA2) autoantibodies, and diabetes.
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
Song et al., Baltimore, United States. In Nature, 2012
RGLs are in close proximity to terminals expressing 67-kDa glutamic acid decarboxylase (GAD67) of parvalbumin-expressing (PV+) interneurons and respond tonically to GABA released from these neurons.
GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.
Baron et al., Linköping, Sweden. In N Engl J Med, 2012
BACKGROUND: The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes.
Novel SNPs of the bovine GAD1/gad67 gene and their association with growth traits in three native Chinese cattle breeds.
Wang et al., China. In Mol Biol Rep, 2010
These results suggest that the GAD1 gene is a strong candidate gene that affects growth traits in cattle.
share on facebooktweetadd +1mail to friends