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Glucosamine-6-phosphate deaminase 1

glucosamine-6-phosphate deaminase, oscillin, GNPDA
Glucosamine-6-phosphate deaminase (EC is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, STEP, V1a
Papers on glucosamine-6-phosphate deaminase
Proteomic Analysis Reveals PGAM1 Altering cis-9, trans-11 Conjugated Linoleic Acid Synthesis in Bovine Mammary Gland.
Lee et al., Changchun, China. In Lipids, May 2015
One up-regulated (RAS guanyl releasing protein 4 isoform 1 [RASGRP4]) and six down-regulated proteins (glucosamine-6-phosphate deaminase 1 [GNPDA1], triosephosphate isomerase [TPI1], phosphoglycerate mutase 1 [PGAM1], heat shock protein beta-1 [HSPB1], annexin A3 [ANXA3], thiopurine S-methyltransferase [TPMT]) were found in MAC-T cells treated with trans-11 C18:1.
Heterogeneity of quaternary structure of glucosamine-6-phosphate deaminase from Giardia lamblia.
Milewski et al., GdaƄsk, Poland. In Parasitol Res, 2015
The oligoHis-tagged versions of glucosamine-6-phosphate deaminase from Giardia lamblia (GlmNagB-HisN, GlmNagB-HisC) were constructed and purified to hear homogeneity, and their kinetic and structural properties were compared to those of the wild-type enzyme (GlmNagB).
Uptake and metabolism of N-acetylglucosamine and glucosamine by Streptococcus mutans.
Zeng et al., Gainesville, United States. In Appl Environ Microbiol, 2014
A transcriptional regulator, designated NagR, was able to bind the promoter regions in vitro, and repress the expression in vivo, of the nagA and nagB genes, encoding N-acetylglucosamine-6-phosphate deacetylase and glucosamine-6-phosphate deaminase, respectively.
Purification and characterization of a urethanase from Penicillium variabile.
Tian et al., In Appl Biochem Biotechnol, 2014
Within the known sequences in NCBI, glucosamine-6-phosphate deaminase and 6-phosphogluconate dehydrogenase get high score as compared with urethanase.
The tertiary origin of the allosteric activation of E. coli glucosamine-6-phosphate deaminase studied by sol-gel nanoencapsulation of its T conformer.
Calcagno et al., Mexico. In Plos One, 2013
The role of tertiary conformational changes associated to ligand binding was explored using the allosteric enzyme glucosamine-6-phosphate (GlcN6P) deaminase from Escherichia coli (EcGNPDA) as an experimental model.
Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder.
Psychiatric GWAS Consortium: ADHD Subgroup et al., Essen, Germany. In Am J Med Genet B Neuropsychiatr Genet, 2013
In the German sample rs206936 (NUDT3) and rs10938397 in the glucosamine-6-phosphate deaminase 2 gene (GNPDA2) were associated with inattention, whereas markers in the mitogen-activated protein kinase 5 gene (MAP2K5) and in the cell adhesion molecule 2 gene (CADM2) were associated with hyperactivity.
Comparative study of Trichoderma gene expression in interactions with tomato plants using high-density oligonucleotide microarrays.
Hermosa et al., Salamanca, Spain. In Microbiology, 2012
Carbohydrate metabolism - the chitin degradation enzymes N-acetylglucosamine-6-phosphate deacetylase, glucosamine-6-phosphate deaminase and chitinase - was the most significantly overrepresented process commonly observed in the three Trichoderma strains in early interactions with tomato plants.
Allosteric kinetics of the isoform 1 of human glucosamine-6-phosphate deaminase.
Calcagno et al., Mexico. In Biochim Biophys Acta, 2011
The human genome contains two genes encoding for two isoforms of the enzyme glucosamine-6-phosphate deaminase (GNPDA, EC
Enhanced drought tolerance in Arabidopsis via genetic manipulation aimed at the reduction of glucosamine-induced ROS generation.
Lee et al., Seoul, South Korea. In Plant Mol Biol, 2010
Scavenging of endogenous GlcN by ectopic expression of E. coli glucosamine-6-phosphate deaminase (NagB) was observed to confer enhanced tolerance to oxidative, drought, and cold stress.
Analyses of shared genetic factors between asthma and obesity in children.
Lasky-Su et al., Boston, United States. In J Allergy Clin Immunol, 2010
RESULTS: One top BMI GWAS SNP from the literature, rs10938397 near glucosamine-6-phosphate deaminase 2 (GNPDA2), was associated with both BMI (P = 4 x 10(-4)) and asthma (P = .03).
Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source.
McConville et al., Melbourne, Australia. In Plos Pathog, 2009
The last step in this pathway is catalyzed by glucosamine-6-phosphate deaminase (GND), which was targeted to glycosomes via a canonical C-terminal targeting signal when expressed as a GFP fusion protein.
Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.
Horjales et al., Ecatepec, Mexico. In Febs Lett, 2003
Sequence analysis and crystallographic structure of GNP1.
Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.
Cao et al., Shanghai, China. In J Cell Biochem, 2003
identification, chromosomal localization and functional analysis of cDNA encoding GNPI/Oscillin homolog named GNPI2.
A novel protein for Ca2+ signaling at fertilization.
Swann et al., London, United Kingdom. In Curr Top Dev Biol, 1997
The sperm factor activity is correlated with a novel signaling protein that we have called oscillin and which may mediate Ca2+ release via a novel mechanism.
A novel signalling mechanism for generating Ca2+ oscillations at fertilization in mammals.
Lai et al., London, United Kingdom. In Bioessays, 1997
Biochemical studies suggest that there exists a novel sperm protein, named oscillin, that specifically comigrates with Ca2+ oscillation-inducing activity.
Calcium oscillations in mammalian eggs triggered by a soluble sperm protein.
Lai et al., London, United Kingdom. In Nature, 1996
This sperm-derived oscillogen, termed oscillin, may represent the physiological trigger for development in mammals.
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